GI A&P Flashcards
(18 cards)
best tests to evaluate liver function
bili, albumin, coag (INR/PT)
Hepatic Portal System
Normal Gallbladder and Vessels
Sphincter of Oddi & Ampulla of Vater location
Arteries of the Abdomen
Pancreatic Enzymes
-
Amylase:
- breaks down carbohydrates
-
Trypsin & chymotrypsin
- start as zymogen or trypsinogen (inactive forms) → become active in duodenum
- prevents autodigestion
- break down proteins
- start as zymogen or trypsinogen (inactive forms) → become active in duodenum
-
Lipase
- breaks down lipids
Acinar Cells
Located in the pancreas
- produce zymogen and trypsinogen
- inactive forms of trypsin and chymotrypsin
- become active when they reach the duodenum → break down proteins
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Why is lipase measured in pancreatitis?
When the pancreatic cells get damaged they release lipase
Which are the fat soluble vitamins?
A, D, E, & K
What digests Carbohydrates and where are they absorbed?
-
digestive enzymes:
- salivary amylase, pancreatic amylase, brush border enzymes
-
Absorption:
- small intenstine
What and where digests proteins?
-
Digestive enzymes:
- pepsin, trypsin, chymotrypsin, carboxypeptidase, brush border enzymes
-
Absorption:
- small intestine
Breakdown, enzymes, and absorption of lipids
-
breakdown/emulsification:
- bile salts from the liver
-
digestive enzymes:
- pancreatic lipase
-
absorption:
- small intestine
Mesenteries of the GI system
What makes up saliva?
- 99.5% water
- electrolytes
- mucus
- salivary amylase: breaks down carbohydrates
- lysozyme: antibacterial enzyme
Secretions of the Stomach
- Parietal cells: HCl, intrinsic factor (required for B12 absorption)
- chief cells: pepsinogen, gastric lipase
- G-cells: gastrin
- enterochromaffin-like cells: histamine
- mucosal cells: alkaline mucus
Where does the majority of nutrient absorption occur in the body?
jejunum
What digestive enzymes are released by the pancreas?
- amylase
- trypsin
- chymotrypsin
- carboxypeptidase
- elastase
- lipase-colipase
- phospholipase A2
- cholesterol esterase - non-specific lipase
- NaHCO3
Lynch Syndrome
- autosomal dominant inheritance
- call hereditary nonpolyposis colorectal cancer
- inherited disorder
- associated with certain cancers:
- colorectal
- stomach
- pancreas
- urinary tract
- ovary/uterus & prostate