GI Disorders Flashcards

(37 cards)

1
Q

What are GERD investigations?

A

Barium swallow
24 hr esophageal ph monitoring
Impedance monitoring (manometry)
Esophageal endoscopy :erosive esophagitis

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2
Q

GERD management

A
  • not compicated : lifestyle modifications
  • complicated: pro kinetics, H2 blockers( ranitidine), PPI
  • surgical
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3
Q

What is the peak age for Functional childhood Abdominal pain?

A

8-9 years

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4
Q

What is the diagnostic investigation of IBD in children?

A

Endoscopy and Biopsy

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5
Q

What is the management of crohns disease?

A

First line : enteral nutrition(polymeric diet), 5asa, prednisolone
Second line: AZAthioprine ; MTX
Third line: infliximab ; surgery

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6
Q

What is the pathological finding of a biopsy of celiac disease

A

Villous atrophy on a jujenal biopsy

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7
Q

What is the serology test to do in celiac disease

A

Anti-tissue transglutaminase IgA
Endomesial antibodies
Anti gliadin

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8
Q

When should infants regain birth weight after losing it?

A

By 2 weeks

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9
Q

What are the energy needs of infants?

A

Ø0 – 3 months 115Kcal/kg/day.

Ø1 – 3 years 95 Kcal/kg/day

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10
Q

Dysphagia associated with achalasia is for what type of food?

A

Solids & liquids

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11
Q

Investigations of Achalasia

A

CXR: air fluid level in dilated esophagus
Barium swallow: bird peak appearance
Manometry: increased intra esophageal pressure
Upper endoscopy

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12
Q

Treatment of Achalasia

A

Endoscopy pneumatic dilatation
Myotomy: laparoscopic, endoscopic, surgical
Botulinum toxin injection (temporary)

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13
Q

What is the peal age for foreign body ingestion in children

A

6 months - 3yrs

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14
Q

Treatment of Foreign Body ingestion

A

Fortunately, most ingested FBs pass
spontaneously. Only 10 – 20% require endoscopic
removal, and < 1% require surgical intervention.

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15
Q

What is the role of upper GI series (barium or gastrograffin) swallow) in corrosive injuries

A

Not valuable in the initial stages of evaluation, only if clinical
suspicion of perforation (use water-soluble contrast not barium).
§ 2-3 weeks post-ingestion, even if the patient is asymptomatic to
evaluate stricture.

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16
Q

Investigations of caustic ingestion

A

CXR
Endoscopy to all symptomatic pts within 24 hrs (not<6 hrs)
Upper GI series (no major role before 2 weeks)

17
Q

Treatment of caustic ingestion

A

Hospital admission & IV Fluids: till evaluation.
v Feeding:
Ø Nasogastric tube: extensive circumferential burns.
Ø Gastrostomy tube: severe extensive esophageal burns.
Ø Jujenostomy tube
v Medications:
Ø Antibiotics: If infection suspected or as prophylasis.
Ø Acid suppression: PPIs.
Ø Corticosteroids: may reduce risk of stricture (Controversial).
v Treatment of complications:
Ø Esophageal dilatation: for strictures 3-6 wks after injury.
Ø Surgical: for perforation and reconstruction of esophagus (If
needed).

18
Q

What is Rumination syndrome

A

people repeatedly & unintentionally
regurgitate undigested or partially digested food from the stomach, re-
Swallow it or spit it out,
it most often occurs in infants and very young
children (3-12 months), and in children with intellectual disabilities.

19
Q

If projectile vomiting presents at 2–7 weeks of age, what disease should be excluded?

A

Pyloric stenosis

20
Q

Cl/p of CHPS

A

§ Non-bilious projectile vomiting, then child is hungry.
§ Olive-shaped palpable mass in Rt upper abd. quadrant.
§ Gastric peristaltic waves (Lt to Rt) in baby’s abdomen.

21
Q

What is the finding of a barium meal in a baby with pyloric stenosis?

22
Q

Investigations of CHPS

A

§ Hypochloremic metabolic alkalosis with a low Na & K as
result of vomiting.
§ Abd. Ultrasound: Pylorus: ► > 4mm wall thickness.
► > 15mm length.
§ Barium meal ± (in doubtful cases): Narrow pyloric canal
(String sign).

23
Q

Management of CHPS

A

§ The initial priority: correct any fluid and
electrolyte disturbance with IV fluids (0.9% saline
and 5% dextrose with K supplements).
§ Definitive treatment by pyloromyotomy:
ØDivision of the hypertrophied muscle down to, but
not including, the mucosa.
ØEither by open procedure or laparoscopically.
§ Postoperatively, the child can usually be fed within
6 hrs and discharged within 2 days of surgery

24
Q

What is sandifer syndrome?

A

Dystonic head and neck. Movements

A complication of GERD

25
Investigations of GERD
24 h esophageal PH monitoring (gold standard) 24 h impedance monitoring Barium study Upper GI endoscopy
26
Management of GERD
``` ØIf CMPA suspected → Trial of hypoallergenic formula) q Acid Suppression: ØReduce volume of gastric contents. ØTreat acid-related esophagitis. § H2 blockers (Ranitidine). § Proton-pump inhibitors (Omeprazole). q Prokinetics: Ø Enhance gastric emptying. § Metoclopramide § Domperidone ``` ``` Surgical management: § Nissen fundoplication (abdominal or laparoscopic procedure): The fundus of stomach is wrapped around the intra-abdominal esophagus ```
27
Rome III Diagnostic criteria for childhood FAP
Episodic or continuous abdominal pain. 2. Insufficient criteria for other FGIDs. 3. No evidence of an inflammatory, anatomic, metabolic, or neoplastic process that explains the symptom. *Criteria fulfilled at least once per week for  2 months before diagnosis
28
Pathology of crohns disease
▪ Skip lesions. ▪ Transmural. ▪ Granulomas
29
Pathology of Ulcerative Colitis
Diffuse. ▪ Mucosal. ▪ Crypt abscesses
30
Treatment of Ulcerative Colitis
Induction:• Prednisolone • Sulphasalazine/5-ASA Maintenance: Sulphasalazine/5-ASA Second line: • Systemic steroids (exacerbation) • Azathioprine Fulminant disease: Surgery + Cyclosporine • Surgery • ?? Infliximab
31
Rome Diagnostic criteria for pediatric constipation
❖ Gold standard definition ▪ → A patient must have  2 of the following symptoms over the preceding 3 months: ➢< 3 spontaneous bowel movements / week. ➢Straining for > 25% of defecation attempts. ➢Lumpy or hard stools for  25% of defecation attempts. ➢Sensation of anorectal obstruction or blockage  25%... ➢Sensation of incomplete defecation for  25%... ➢Manual maneuvering required to defecate for  25%
32
Medical management of constipation
``` ▪ Enemas or manual evacuation (if severe). ▪ Movicol (PEG). ▪ Lactulose (Osmotic). ▪ Stimulant laxatives: ➢Senna. ➢Sodium picosulphate. ```
33
Diagnosis of Esinophiloc esophagitis
Esophageal biopsy: inflamation + peak value of ≥15 eosinophils /HPF (or 60/mm2). Increased serum IgE and peripheral eosinophilia Endoscopy : Stacked circular rings (appearance of a tracheal (trachealisation)
34
What is the first line management of eosinophilic esophagitis
Dietary therapy: Avoidance of allerge
35
Management of ana acute attack of Cow milk protein allergy
ØMild reaction (no Cardiorespiratory symptoms): ►► Antihistamines. ØSevere reaction: ►►I.M. Epinephrine (adrenaline) by auto-injector (Epipen) Child/parent should carry at all times.
36
Most common cause of infectious gastroenteritis in children
Rota virus
37
What is the cutoff duration for chronic abdominal pain
2 months