GI Drugs Flashcards
(22 cards)
H2 Blockers action
block receptors and decreases gastric acid production
Examples of H2 blockers
Ranitidine (zantac), famotidine (pepcid), nizatidine (Axid)
Safest H2 to use with liver dysfunction
axid
when do you give H2 blocker
before meals, one hr after antacids, at bed time
PPI ending
prazoles
PPI action
decreases acid in stomach
PPI indications
peptic and duodenal ulcers, GERD
When do you give PPI
before meal
Examples of PPI
esomeprazole (nexium), omeprazole (prilosec), pantoprazole (protonix)
Muscosal protectant action
coats ulcer to protect from acid
example of mucosal protectant
sucralfate (caralfate)
interactions with mucosal agents
dilantin, cipro, penicillamines
When do you take mucosal agents and what food to eat
before bed on empty stomach, high fiber food
example of osmotic laxative
lactulose
how does osmotic laxative work
draws water into colon
how do emollient stool softners work
water accumulation to lubricate stool
example of emollient
colace (docusate)
contraindications with laxatives
undiagnosed abdominal pain, inflammatory disorders, spastic colon, bowel obstruction
how do antidiarrheals work
decreases motility dont use for more than 2 days
examples of antidiarrheals
opiates, somastostatin analog
antiemetics action
inhibits chemoreceptor trigger zone and decreases sensitivity of vestibular apparatus
examples of antiemetics
hydroxzine (vistaril), promethazine (phernergan), ondasteron (zofran)
