GI: endings for drug classes

Question 1

-tidine

Answer 1

H2 Rec Antagonists

Question 2

-prazole

Answer 2

PPIs

Question 3

any weak base
or
cation/anion + hydroxide

Answer 3

Antacids

Question 4

Misoprostol

Answer 4

Prostaglandin

Question 5

Bismuth Subsalicylate

Answer 5

• Mucosal Protective agent
• some antimicrobial properties
• Anti Diarrheal via fluid and electrolyte transport modification

Question 6

Sucralfate

Answer 6

Mucosal Protective agent

Question 7

list drugs in quad tx

Answer 7

Bismuth Subsalicylate 
Metronidazole 
Tetracycline 
PPI 
x 14 days

Question 8

List triple therapy tx

Answer 8

Clarithromycin
Amoxicillin (allergy to PNC— Metronidazole)
PPI

Question 9

-azine

Answer 9

Phenothiazine

*anti emetic

Question 10

-setron

Answer 10

5 HT3 Rec Blocker

*anti emetic

Question 11

Metoclopramide

Answer 11

substituted Benzamine

*anti emetic

Question 12

-peridol

Answer 12

Butyrophenones–>*anti emetics

ALSO

Dopamine Receptor Antagonists–prokinetic laxative

Question 13

List the benzos used as anti emetics

Answer 13

Lorazepam

Alprazolam

Question 14

List the corticosteroids used as anti emetics

Answer 14

Dexamethasone

Methylprednisolone

Question 15

-pitant

Answer 15

Substance P/Neruokinin receptor antagonists

*anti emetics

Question 16

-inol

Answer 16

Cannabinoids

Question 17

Lubailone

Answer 17

Cannabinoids

Question 18

-zine

Answer 18

antihistamines

Question 19

diphenoxylate

Answer 19

anti motility

Question 20

loperamide

Answer 20

anti motility

Question 21

aluminum hydroxide

Answer 21

absorbent

Question 22

methylcellulose

Answer 22

• adsorbent–diarrhea

* Bulk laxative

Question 23

Senna

Answer 23

irritant and stimulant laxative

Question 24

Bisacodyl

Answer 24

irritant and stimulant laxative

Question 25

castor oil

Answer 25

irritant and stimulant laxative

Question 26

Psyllium

Answer 26

bulk laxative

Question 27

Bran

Answer 27

Bulk laxative

Question 28

Magnesium citrate

Answer 28

Saline cathartic

Question 29

Magnesium hydroxide

Answer 29

Saline cathartic

Question 30

Polyethylene glycol (PEG)

Answer 30

colonic lavage (osmotic laxative)

Question 31

Lactulose

Answer 31

Osmotic laxative

Question 32

Docusate sodium and docusate calcium

Answer 32

Stool softeners (emollient laxatives)

Question 33

Mineral oil

Answer 33

Lubricant laxative

Question 34

Glycerin suppositories

Answer 34

Lubricant laxative

Question 35

Colace

Answer 35

stool softener

Question 36

Lubriprostone

Answer 36

Chloride channel activators (secretory agent)

Question 37

Linaclotide

Answer 37

Chloride channel activators (secretory agent)

Question 38

doperidone

Answer 38

Dopamine Receptor Antagonists--prokinetic laxative

Question 39

Cisapride

Answer 39

Serotonin 5HT Receptor Agonist-- prokinetic laxative

Question 40

Tegaserod

Answer 40

Serotonin 5HT Receptor Agonist-- prokinetic laxative

Question 41

Motilin

Answer 41

prokinetic laxative (hormone)

Question 42

Macrolides (esp erythromycin)

Answer 42

prokinetic laxative (ABX)

Question 43

Dicyclomine

Answer 43

``` Antispasmodics/Anticholinergic (antimuscarinic) agents IBS drug (C and D) ```

Question 44

Hyocyamine

Answer 44

``` Antispasmodics/Anticholinergic (antimuscarinic) agents IBS drug (C and D) ```

Question 45

What is the only ABX approved for IBS

Answer 45

Rifaximin

Question 46

Sulfasalazine

Answer 46

5-aminosalicylate for UC 1st line

Question 47

Mesalamine

Answer 47

5-aminosalicylate for UC 1st line

Question 48

list the corticosteroids used in tx for IBD (4)

Answer 48

Budesonide Hydrocortisone Prednisone Methylprednisoloine

Question 49

-mab

Answer 49

Biologic agents used for IBD

Question 50

Infliximab

Answer 50

TNF inhibitor (IBD)

Question 51

Adalimumab

Answer 51

TNF inhibitor (IBD)

Question 52

Certolizumab

Answer 52

TNF inhibitor (IBD)

Question 53

Golimumab

Answer 53

TNF inhibitor (IBD)

Question 54

Vedolizumab

Answer 54

alpha-4 integrin inhibitor (IBD)

Question 55

Ustekinaumab

Answer 55

IL-12/23 Inhibitor (IBD)

Question 56

Methotrexate

Answer 56

Immunomodultor for IBD

Question 57

Azathiprine

Answer 57

Thiopurine for IBD

Question 58

Mercaptopurine

Answer 58

Thiopurine for IBD