GI smooth muscle spasm

Question 1

cause of spasm

Answer 1

IBS,IBD, bowel colic pallitative care

Question 2

antimuscarinic name and effect

Answer 2

acts on muscarinic receptor reduce gi motility
affects parasympathetic “rest and digest” system, therefore has s/e

atropine (less used s/e)
dicycloverine
propantheline bromide
hyoscine butyl bromide

Question 3

hyoscine hydrobromide uses

Answer 3

motion sickness

Question 4

Antimuscurinic s/e

Answer 4

“cant see, cant pee, cant poo , cant spit”
blurred vision, urinary retention , constipation, dry mouth
other
tachycardia, palpitation and arrhythmia (inc HR)
Drowsy
confusion elderly
raise IOP acute angle closed glaucoma
pupil dilation
reduce bronchial secretion

Question 5

caution in antimuscarinic

Answer 5

• susceptibility to acute angle closure glaucoma
• CVD - arrhythmia, tachycardia
  -hyperthyroid due to tachycardia

Question 6

c/I in antimuscarinic

Answer 6

-prostatic enlargement, urinary retention
- narrow angle closure glaucoma
- gi obstruction, paralytic ileus, toxic meg
-mysthenia graves

Question 7

caution in buscopan injections

Answer 7

risk of adv in cardiac patients

Question 8

antispasmodic example