GI: Treatment of Diarrhoea + Constipation Flashcards Preview

Year 1: Drug Revision > GI: Treatment of Diarrhoea + Constipation > Flashcards

Flashcards in GI: Treatment of Diarrhoea + Constipation Deck (17)
Loading flashcards...
1
Q

What family of drugs do loperamide and codeine belong to?

A

Opiates

2
Q

What are these opiate based drugs used to treat with regards to the GI system?

A

Diarrhoea

3
Q

How do loperamide/codeine affect peristalsis?

A

They decrease peristalsis

4
Q

How do loperamide/codeine affect segmentation?

A

They increase segmentation

5
Q

How do loperamide/codeine affect fluid absorption?

A

They increase fluid absorption

6
Q

What are the side effects of loperamide/codeine?

A

Constipation
Drowsiness
Urinary retention

7
Q

When is use of these opiate based drugs contraindicated?

A

C.Diff induced colitis

Acute ulcerative colitis

8
Q

Which receptors do opiates activate? What is the result of this?

A

N-opiod receptors. Hyper polarisation which inhibits enteric neurones

9
Q

What are 5-ASA drugs such as mesalazine used to treat?

A

Ulcerative colitis

10
Q

What properties does mesalazine have?

A

Anti-inflammatory

11
Q

What are the side effects of 5-ASA drugs

A

Can worsen diarrhoea
Cramps
Nausea

12
Q

Give examples of bulk forming laxatives

A

Methylcellulose

Ispagala husk

13
Q

Give examples of stimulant laxatives

A

Senna

Bisacodyl

14
Q

Give examples of osmotic laxatives

A

Lactulose

Macrogols

15
Q

What are laxatives used to treat?

A

Constipation
Painful defecation
Faecal impaction
To clear bowel before endoscopy/Surgery

16
Q

Which laxative is used in the treatment of hepatic encephalopathy?

A

Osmotic, e.g. lactulose

17
Q

What are the side effects of laxatives?

A

Abdominal pain

Flactulence