giardiasis Flashcards
1
Q
cases
A
280 million and 10,000 deaths each year
susceptibility depends on age, previous exposure and immune status
2
Q
caused by
A
giardia duodenalis - G. lamblia and g intestinalis
3
Q
transmission
A
water and foodborne
person to person
4
Q
distribution
A
worldwide
5
Q
life cycle
A
infective cyst eaten, excess in lower duodenum to trophozoites which multiply by binary fission
contamination of food an water and fomites with infective cysts
excystation occurs in duodenum due to combination of bile salts and high ph
6
Q
diagnosis
A
microscopy
entero string test - sample from upper intestine - useful when suspected but not detected in stool
giardia/cryptosporidum quik chek RDT
7
Q
treatment
A
1st line - metronidazole for 5 days
tinidazole as a single dose
furazolidone
reserve - nitazoxanide albendazole quinacrine mepacrine paromomycin (used in pregnancy)
