GIT Question Bank(From 801 Page) Flashcards
1
Q
What are the drugs causing Chronic or relapsing diarrhea?
A
NSAIDS,Aminosalycilates,SSRI
2
Q
Biochemical changes in suspected Malabsortion?
A
Decrease Albumin,zinc,ca,mg,po4
3
Q
Haematological changes in malabsorption?
A
Microcytic anemia,macrocytic anemia & increase PT (k deficiency)
4
Q
investigations for malabsorption?
A
Biochemical,small gut,pancreas & Bile salt functions
5
Q
Lung conditions causing wt loss?
A
TB,COPD,Empyema,Ca(small call especially)
6
Q
Chronic infection Causing wt loss?
A
HIV,TB,Brucellosis,Gut infestation
7
Q
Neurodegenarative Diseases causing wt loss?
A
Dimentia,PD,MND
8
Q
Cardiac causes of wt loss?
A
Ccf,IE
9
Q
Drugs causing constipation?
A
Opiates,Anti cholinergic,CCB(verapamil),Iron,Aluminium containing Antacids
10
Q
Neurological Causes of wt loss & constipation?
A
Constipation:PD,Cerebrovascular accident,MS,Spinal cord lesion
Wt loss:PD,Dimentia,MND
11
Q
Metabolic causes of constipation?
A
DM,Hypercalcemia,Hypothyroidism,pg
12
Q
What are the clinical features of Small,large and malabsorption diarrhea?
A
Small: large volume watery,bloating,mid abdominal cramp
Large:Blood and mucus,lower abdominal cramp
Malabsorption:steatorrhea, undigested food,wt loss and nutritional disturbances
13
Q
Metabolic causes of abdominal pain?
A
DM,AIP,Hypercalcemia
14
Q
Drug causes of abdominal pain?
A
Steroid,azathiprine,Alcohol,lead
15
Q
Haematological causes of abdominal pain?
A
Sickle cell anemia,hemolysis
16
Q
Neurological causes of abdominal pain?
A
SC lesion,radiculopathy,Tabes dorsalis
17
Q
Most common cause of chronic Abdominal wall pain(CAWP)?How to confirm clinically?
A
Anterior cutaneous nerve entrapment syndrome.
Carnett’s sign(Pain is unchanged or worse after abdominal muscle is tensed)
18
Q
GI causes of oral ulcer?
A
Chron’s & coeliac disease
19
Q
Dermatological causes of oral ulcer?
A
Dermatitis Herpetiformis
Lichen planus
Immunobullous disease
Erythema Multiforme
20
Q
Drugs causing oral ulcer
A
Nicorandil
NSAID
MTx
Penicillamine
Ace-I,ARB(losartan)
Cytotoxic drugs
SJS
21
Q
Infection causing oral ulcer?
A
Candida
HSV
HIV
TB
Syphilis
22
Q
Who are at risk for Apthous ulcer?
A
Woman prior to menstruation
23
Q
In candidiasis odynophagia and dysphagia indicates?Rx?
A
Pharyngeal and oesophageal
1.Topical miconazole/nystatin
2.oral fluconazole
24
Q
In old age dry mouth occur in 40% people..Base line salivary flow? And saliva on stimulation?
A
Baseline falls but on stimulation unchanged
25
#GERD
Neverthless all patient Develos Oesophagitis,Barrets or strictures are found to have??
Hiatus Hernia
26
which anemia occurs in GERD?
IDA
27
Indication of Rx in Barret's Oesophagus?
Symptoms of gerd or strciture
28
Severe chest pain+severe vomiting+Dysphagia Dx?Preferred Inv?
Gastric volvulous due to twisting of large Hiatus hernia..
Inv:CXr(air bubble on chest) & Barrium swallow
29
Inv of GERD?
1.Young with no warning feature-No inv
2.Investigation of choice: UGIE
3.Gold: 24Hours pH (<4 for more than 6% of study time)
4.Impedance test - to detect weakly acidic or alkaline reflux
30
Drugs causing Oesophagitis?
Bisphosphonates
Tetracyclines
NSAIDS
Potassium supplement
31
1.commonest benign tumor of Oesophagus?
2.Commonest Malignant tumor?
3.Commonest in lower 3rd
1.Leomyoma
2.Squamous cell ca
3.Adenocarcinoma
32
Complication of plummer vinson syn
Squamous cell ca of oesophagus
33
Risk factors of squamous cell ca of Oesophagus
1.Smoking
2.Alcohol
3.betel nut
4.achalasia Cardia
(২ টা post)
4.Post cricoid web(plummer vinson)
5.post caustic stricture
6.Coeliac disease
7.Tylosis(familial hyperkeratosis of palm and sole
34
Drug causing Oesophageal stricture?
Bisphosphonates
35
Which mal absorption causes proximal muscle weakness?
Vit-D
36
Which mal absorption causes muscle wasting?
Protein
37
Which malabsorption causes purpura and bruising?
Vit c & K
38
Which mal absorption cause poor wound healing?
Zinc,vit C, protein
39
C/f of Pharyngeal pouch?
IOC?
Dysphagia+halitosis+regurgitation + gurgling after swalloimg
IOC: Barrium swallow
40
#Achalasis
1.Associated Autoimmune Disease?
2.Defective release of which neurotransmitter causes achalasia? Degeneration of which cell?
3. Which infection ks clinicall indistinguishable from Achalasia?
1.৩ টা Rheumatic (SLE,RA,sjogre) আর Type 1 DM
2.NO, degeneration of Ganglionic cell
3.Chagas diseas(T.cruzi)
41
Investigation of Achalasia cardia
1.IOC: UGIE (to exclude pseudo achalasia - ca of gastric fundus)
2.confirm by Manometry
3 Barrium meal - Rat tail (tappered narrowing)
42
Latest endoscopic Rx of achalasia
POEM (peroral endoscopic myotomy)
43
Which therapy is needed after Hellers operation of achalasia?
PPI
44
What is nutcracker oesophagus?
Rx?
-Extremely Forceful peristaltic activity leading to episodic chest pain & dysphagia
Rx:Nitrates & nifedipine
45
Secondary causes of oesophageal dysmotility
1.Crest syndrome
2.Dermatomyositis
3.RA
4.Myasthenia Gravis
46
Commonest site of Gastric ulcer?
90% are located in lesser curve within antrum/at the junction between body and antral mucosa
47
Commonest site of duodenal ulcer?
Anter wall 50%
48
Causes of chronic non specific Gastritis?
H.pylori
Autoimmune(pernicious)
Post gastrectomy
49
Properties of H.pylori
1.Gm negative
2.spiral
3.flagella
4.produce urease
50
Virulence factors of H.pylori
1.vaca
2.Caga
3.baba
4 oipa(outer inflammatory protein A)
51
Adhesion factor of H.pylori?
bAba-with Lewis b antigen on epithelial cell
52
Which variety produce duodenal ulcer?
Antral predominent (Hypergastrinemia)
53
Which variety causes Gastric cancer?
Corpus/gastric variant causes gastric atropy and hypochlorhydrua & by converting Dietary nitrates to mutagenic nitrites
54
Which hematological disease is associated with pud?
ITP
55
For H.pylori which test is Gold?
Culture. It can define antibiotic sensitivity too
56
Best test for population screening?
Serology
57
Commonest A/E of eradication therapy?
Diarrhoea (50%)
58
Extra gastric disorder where H.pylori eradication is indicated?
1.ITP
2.IDA
59
Gastric disorder where H.pylori eradication is indicated?
1.PUD (old or new)
2.Dyspepsia
3.previous endoscopic resection of early gastric ca
4.Extranodal marginal lymphoma of MALT type
5.Long term NSAID and kow dose aspirin
6.unexplain B12 deficiency
60
H.pylori eradication is indicated in GERD..T/F?
F
61
What are the indepandant risk factor for PUD?
H.pylori
NSAID
62
Which anemia is most common after subtotal gastrectomy?
IDA
63
Most stricking symptom of pud perforation?
Sudden severe pain
64
The most common site for GOO?
Pylorus
65
In GOO, Succation splash is seen after 4hr of last meal.What is diagnostic of GOO?
Visible peristalsis
66
Commonest site of Gastrinoma(zollimger Ellison syndrome)?
Pancreatic head/proximal duodenal wall
67
Gastrinoma/Z.E.S is associated with?
MEN 1
68
Presentation of Gastrinoma/ZES?
Severe,often multiple PUD at unusual site like post bulbar duodenum, jejunam,oesophagus.Duration is short and poor response to standard therapy.Diarrhoea in 1/3rd case
69
Test for gastrinoma/ZES?
Secretin stimulation test
(Dramatic and paradoxical rise in gastrin level)
70
Which diet are responsible for gastric ca?
Smoked, salted or prickled foods,nitrates and nitrites
71
Which vit responsible for Gastric ca?
CA(remember Gastric cancer is caused by ca)
72
Urea producing oragnism?
PUNCH
proteus(alkalaine urine)
Ureaplasma (renal calculi)
Nocardia
Crycptococcus
H.pylori
73
H.pylori associated gene causing Gastric ca?
CagA
74
Risk factors for Gastric Ca?
1.H.pylori
2.smoking
3.Alcohol
4.Diet & Vitamin
5.gastric adenomatious polyp
6.Diffuse gastric ca (CDH1 mutation)
7.FAP
8.previous partial gastrectomy (>20 yrs)
9.pernicious anemia
10.menitriers disease
75
Which histological type of gastric ca is more common?
Intestinal
76
What are the paraneoplastic syndrome of Gastric ca?
Thrombophlebitis(Trousseaus sign)
Achanthosis Nigricans
Dermatomyositis
77
T/F Lymphoid tissue normally present in normal stomach.
F
78
Which chromosomal translocation is associated with gastric lymphoma?
t(11:18)
79
#Gastric carcinoid(neuroendocrine)
1.commonest cell?
2.Commonest site?
3.best inv?
1.ECL and other endocrine cell
2.fundus and body in long standing pernicious anemia
3.EUS is best investigation
80
GIST arises from which cell?
Associated Gene?
Interstitial cells of cajal(stillete)
C-kit proto onco gene
81
Common gastric polyp?
Fundic gland polyp
Hyperplastic polyp
Adenomatous polyp
82
Causes of Gastroparesis?
Inherited
Diabetic neuropathy (*)
Systemic sclerosis
Myotonic dystrophy
Amyloidosis
Drugs: CCB,OPIATES,ANTI CHOLINERGIC (TCA & PHENOTHIAZINES)
83
Coeliac disease associated HLA?
DQ2 & DQ8
84
Coeliac disease associated Ag and ab?
Anti endomyseal ab(ttg ag)
IgA mainly (IgG in IgA deficiency)
85
Causes of subtotal villous atrophy?
WiZ এর HIV আর Treatment Radiation দিয়ে CLD হয়ে G(2) elo
whipples dis
Hiv enteropathy
Tropical sprue
Radiation
Coeliac disease
Lymphoma
Dermatitis Herpetiformis
Gammaglobulinemia(hypo)
Giardiasis
86
For mucosal healing in coeliac disease?
Glutein free diet
87
Neurological complications of Coeliac disease/
Encephalopathy
Cerebellar atrophy
PN
Epilepsy
88
What is key to Mx of Coeliac disease?
Dietetic follow up
89
#DermatitisHerpetiformis
1.Lesion & site?
2.Immunoglobulin?
3.Biopsy finding?
4.1st line Rx and drug
1.Lesion & site? Crops of intense itchy blister on Knee, elbow,back and buttock
2.Immunoglobulin?IgA (linear/granular) at Dermo Epidermal junction
3.Biopsy finding?- partial villous atrophy
4.1st line Rx and drug
Usually response to Gluten free diet
Some pt need DAPSONE
90
#Tropical Sprue
1.Tropical Countries?presentation?
2.Rx?
1.West indies,southern india,Malaysia,indonesia.. Condition often begins after an episode of diarrhoeal illness
2.Tetracycline 250mg 4 times-28 days(মনে রাখব t এর জন্য T)
91
#SIBO
1.What are the motility disorders causing SIBO?
Diabetic autonomic neuropathy and Systemic sclerosis
এগুলা ইউজুয়ালী gastroparesis/intestinal obstruction করে।কিন্তু এখানে ডায়রিয়া করবে।মাথায় রাখা লাগবে।
92
#SIBO
Which immune related disorder causes #SIBO?
Hypogamma globulimemia!
এটা subtotal villous atrophy ও করে।মাথায় রাখবি
93
#SIBO
Most common cause of recurrent Gastrointestinal infection in SIBO?
Giardiasis
94
#SIBO
1.Gold standard investigation for SIBO?
2.Non invasive test?
1.Culture of small bowel aspirate obtained at endoscopy is the GOLD
2.Non invasive- Hydrogen breath test
95
#SIBO
1.First line Treatment?
A course of Broad spectrum Antibiotic for 2 weeks (Rifaximin) /cipro/metro/amoxicillin
96
Which antibiotic is not absorbed from the GUT after oral administration?
Rifaximin
97
#Whipples diseases
1.causative organism is Gm positive or negative?
Gm Positive bacilli
98
#whipples disease
1.which group of ppl affected?
2.Foamy macrophage deposited in?
3.which mal absorption occurs?
4.which system affected?
1.Middle aged men of europe
2.Lamina propria causing lymphatic obstruction
3.Fat malabsorption
4.Almost All system
99
#whipples disease
1.First symptom?
2.Commonest GI symptom?
3.Fever?
4.Endocarditis?
1.Joint symptom(Large joint seronegative)
2.Wt loss (90%),Diarrhoea(75%)
3.Mild fever is common
4. Endocarditis can occur in late phase
100
#whipples disease
Dx and Treatment?
Dx: Small bowel biopsy(jejunal) + PCR
Rx:2wks ceftriaxone 2g followed by co trimoxazole 1 year...if relaps, repeat(usually CNS) same treatment + doxycycline,hydroxychloroquine
101
#Coeliac disease
Hyposplenism is found in Coeliac disease..T/F
True
102
#Bile Acid Diarrhoea
1.Causes of Bile Acid Diarrhoea?
Type 1: Terminal ileal disease(Ileal resection & chrons disease)
Type 2: idiopathic
Type 3: other causes of malabsorption
103
#Bile Acid Diarrhoea
1.Investigation of Bile Acid Diarrhoea?
2.Treatment?
1.
-75 (SEHCAT)
-Non invasive 7alpha hydroxyxholestenone
2.Rx: Colestyramine,colesevelam
104
Consequences of Ileal Resection?
1.watery diarrhoea (decrease Bile absorption)
2.Gall stone(lithogenic bile formation due to decresed bile salt pool)
3.Impaired fat & B12 absorption
4.oxalate stone of kidney(funabsorbed bile binds to calcium and oxalate become free)
মনে রাখব দুইটা stone (Bile and renal),B12, diarrhoea & fat mal absorption
105
#Radiation Enteropathy
1.common sites?
1.Terminal Ileum
2.Sigmoid colon
3.Rectum(commonest)
106
#Radiation Enteropathy
1.common complications?
1.proctocolitis
2.Bleeding from talengiectasia
3.Small bowel stricture
4.Adhesions
5.Fistula:Recto vaginal,colovesical and Enterocolic
6.Malabsorption(SIBO,BILE ACID DIARRHOEA)
107
#Abetalipoprotinemia
1.which lipoprotein deficiency?
2.Associated conditions?
1.Apo-B - failure to Chylomicron formation leading to failure of fat soluble vitamins absorption
2.
a.Acanthocytosis
b.Retinitis pigmentosa
c.Cerebellar & Dorsal column sign
108
#Protein losing Enteropathy!
Peripheral oedema and hypoprotienemia in context of normal LFT and absent protienurea..
How to confirm?
1.Fecal clearance of alpha 1 antitrypsin measurement
2.51 cr lebelled albumin after IV injection
109
#Protein losing Enteropathy
1.Common causes?
2.Cardiac Cause?
3.Connective tissue disorder cause?
4.Lymphatic obstruction?
#Protein losing Enteropathy
1.Common causes?-Ulcerative গুলা
2.Cardiac Cause?- Constrictive pericarditis
3.Connective tissue disorder cause?-SLE
4.Lymphatic obstruction?
-Intestinal Lymphactesia
-constrictive pericarditis
-lymphoma
110
What is diaphram disease?
Intense submucosal fibrosis and circumferencial stricturing due to NSAID
111
Common site of intestinal ulcer?Infection causing intestinal ulcer?
ILeum.
Infection:TB,Typhoid,Yersenia enterocolitica
112
#Meckels diverticulum.
Commonest GIT anomaly
Important measurements?
★0.3-3% ppl(2%)
★100cm away from Ileocecal valve
★5cm in diameter
★Complication arise within 2years of life
113
#Meckels diverticulum
Common ectopic tissue?
1.Gastric mucosa-50%
2.colonic
3.pancreatic
4.Endometrial
114
#Meckels
Complications?
1.PUD
2.Perforation
3.Intusseption
4.Diverticulitis
5.Obstruction
115
Food intolerance are immune mediated.T/F?
F..They are not immune mediated...Resulting from either pharmacological(tyramine,histamine,monoaodium glutamate) or metabolic(lactase deficiency) or other Mechanism
116
#Lactose intolerance
90% adult lack Lactase enzyme which convert Lactose to glucose and galactose prior to absorption.In primary -jejunal morphology is normal
In lactase deficiency what occurs?
Unhydrolyzed lactose enters in colon where bacterial fermantation produce
-volatile short chain fatty acids
-Hydrogen
-Co2
117
#Lactose intolerance
1.Correct diagnosis is suggested by?
2.Non invasive test?
1.clinical improvement after withdrawal of lactose
2.Lactose H2 breath test
118
Most common small intestinal benign tumor?
Periampullary Adenoma
119
Drugs causing chronic intestinal pseudo obstruction?
Opiates
Drugs with anti cholinergic effect (TCA,phenothiazines)
120
Which paraneoplastic syndrome is associated with chronic intestinal pseduo obstruction?
Small cell lung ca (myenteric plexus disorder)
121
Example of neoplastic polyp with common site?
1.Conventional Adenoma- throughout colon but larger one in distal colon and rectum
2.Sessile serrated Adenoma:Right colon
3.Traditional serrated Adenoma: Distal colon
122
Risk factor for malignant chancge of polyp?
1.Size >2cm
2.Multiple polyp
3.Serrated polyp (except small rectal hyperplastic polyp)
4.villous architecture
5.High grade dysplasia
123
Different gene in classical Adenoma-carcinoma
1.Early Adenoma-APC Gene
2.Intermediate- KRAS gene
3.Late-DCC/SMAD4
4.CA-Tp53
124
Different Gene in Serrated neoplasia pathway?
Sessile Serrated adenoma- BRAF+IGFBP7 এটা থেকে Ca হবে MLH1 (HNPCC/LYNCH) দিয়ে
Traditional Serrated Adenoma: BRAF+KRAS এতা থেকে ca হবে MGMT
125
#Risk factors of colorectal ca
1.Factors decrese risk?
1.Dietary fibre & fruits, vegetables
2.Ca,Folic Acid,omega 3 FA
3.Aspirin,NSAIDS,STATINS
126
#Risk factors of colorectal ca
1.which operation increase risk?
Cholecystectomy
Ureterosigmoidostomy
127
#Risk factors of colorectal ca
Which diet increase risk?
Red meat& saturated animal fat
128
#Risk factors of colorectal ca
Type 2 DM increase risk T/F?
T
129
#Risk factors of colorectal ca
Which vitamin decrease risk?
Folic Acid
130
#Risk factors of colorectal ca
Which mineral decrease risk?
Calcium
131
#colorectal ca
1.Right vs left colon?
1.Right colon- Anemia & occult bleeding or altered bowel habit.But obostruction is a late feature
2.Left colon- Fresh per rectal bleeding & Early obstruction
132
#colorectal ca
1.Investigation of choice?
2.Helpful investigation for F/U?
3.Most important determinent of Prognosis?
1.Colonoscopy
2.CEA
3.TNM staging at Diagnosis
133
#Non Polyposis Syndrome
Commonest Hereditery Cancer syndrome.(SBA)
1.Synonym? gene?
2.Mean age of onset?
3. Proximal or distal?
4.Diagnosis?
5.Prevention?
1.Lynch syndrome.HNPCC gene
2.45 years.
3.2/3rd proximal tumor unlike sporadic
4.Criteria+ microsatellite PCR
5.Aspirin reduce risk
134
#FAP & MAP
এগুলা হচ্ছে Polyposis syndrome
FAP(APC) is AD whereas MAP(MUTYH) is AR.
Apc তে Truncated Mutation হয়।(loss of function)
বাকী গুলা gain of function
135
#FAP
Commonest tumor & Site?
Periampullary Adenoma(Duodenal)
136
#FAP
T/F Tamoxifen and NSAID have protective role in Desmoid FAP
T
137
#FAP
100% predictive of FAP
CHRPE
138
#FAP
What is Turcot syndrome?
FAP+ CNS TUMOR (ASTROCYTOMA/MEDULOBLASTOMA)
139
#HNPCC
Modified amsterdam criteria?
- 3 or more relative at least 1 first degree
-2 or more generation
-one member affected before 50y
- FAP excluded
140
#FAP
Extra intestinal features?
141
#FAP
Extra intestinal features?
1.CHRPE
2. Gardner syndrome-Osteoma,epidermoid,dental abnormality
3.Desmoid tumor
4.other malignancy (Brain,thyroid,adrenal,liver)
142
Gardner syndrome is associated with?
FAP(OSTEOMA,EPIDERMOID& DENTAL ABNORMALITY)
এখানে কিন্ত Desmoid নাই
143
What are GIT polyposis syndrome?
Neoplastic: FAP&peutz jeghers
Non neoplastic:Juvenile polyposis,Cowden disease,cronkhite canada
144
GIT polyposis associated with oesophageal polyp?
1.cowden
2.cronkhite canada
সব C গুলা Oesophagus মনে রাখব
145
GIT polyposis most commonly causing small bowel polyp?
Peutz jegher
146
GIT polyposis most commonly causing colonic l polyp?
FAP
147
Cowden syndrome(PTEN) associated with?
Congenital anomalies
Oral and cutaneous Hamartoma
Thyroid and breast ca
148
GIT polyposis most commonly causing intussusception and pigmentations?
Peutz jegher
149
#peutz jegher syndrome
1.Gene and mutation?
2.triad?
3 essential other examination
1.STK11, truncating mutation
2.small bowel polyp+mucocutaneous pigmentation+AD pattern.
3.Men: Testicular exam
Women: pelvic exam, cervical smear and regular mammography
150
#Diverticulosis
Common site?
What is left sided appendicitis?
Sigmoid colon & Descending colon
Diverticulitis is lt sided appendicitis
151
#Laxative
Bulk forming?
Ispagula,methyl cellulose
152
#Laxative
Stimulant?
Docusatw,bisacodyl,senna,dantron
153
#Laxative
Osmotic?
Lactulose,lactitol,mg salt
154
#Laxative
Serotonergic?
Prucalopride
155
#Laxative
Prosecretory?
Lubiprostone
156
#Laxative
Fecal softener?
Docusate,arachis oil enema
157
In several idiopathic constipation which laxative should be avoided?
ইসুপগুল (Bulking)
158
#Laxative abuse
1.Tiger skin occur due to?
Accumulation of lipofuscin pigment in macrophage in laminapropria
159
#Laxative abuse
1.what is cathartic colon? ★★★
Megacolon due to laxative abuse..Barium anema shows
featurelesa mucosa loss of haustra,shortening of bowel
160
★RET oncogene
Gain of function: MEN 2
Loss of function : Hirschprung
মনে রাখবো Hirschprung - Harabe(loss)
161
Causes of Acute colonic pseudo obstruction?
surgery,trauma,burn
RF(uremia),respiratory failure
Drugs:Opiates,phenothiazines
Diabetic autonomic neuropathy
Electrolytes: decrease K&mg
162
Causes of both acute and chronic obstruction?
Diabetic AN
Opiates, phenothiazines(TCA শুধু chronic করে)
163
T/F
Fecal impaction causes fecal incontinence?
True
164
T/F
Anxiety causes pruritus Ani
T
165
#IBD
Which inflammatory markers are associated with IBD?
Tnf alpha,IL12&23
166
#IBD
Which infection is prevented by IBD?
TB
167
#IBD
Which operation protect from UC?
Appendicectomy
168
#IBD
Genetic factors of IBD..which genetic factor is associated with severe UC?
HLA-DR 103(Severe UC)
Hnf4alpha
LAMB1
CDH1
169
#IBD
Pseudopolyp,crypt,Thumb pitting mucosa,lead pipe, limited to mucosa are associated with?
UC
170
#IBD
Cobblestone,rose thorn,string sign?
Non caseating granulona?
CD
171
#IBD
What is curative for UC?
Colectomy
172
#IBD
What is typical for UC?
Crypt abscess
173
#IBD
5-ASA& MtX
5 ASA has no role in CD
mTX has no role in maintenance in UC
174
#IBD
What remains the mainstray treatment of CD?
Glucocorticoids
175
#IBD
In UC bloody diarrhoea +mucus+ abdominal cramp indicates?
Left sided colitis/extensive colitis
176
In UC per rectal bleeding+mucus+tenesmus indicates?
Proctitis
177
What are the cardinal features of UC?
Rectal bleeding(proctitis)+mucus+Bloody diarrhoea (left sided/extensive colitis)
178
#IBD
Commonest site of CD?
Ileal/ileocolonic(40%)
Involve perianal but Spare rectum★★★
179
#IBD
In CD feature of UC but rectal sparing..Site?
Chrons colitis
180
#IBD
In CD Acute/chronic pseudoobstruction.Site?
Ileocolic
181
#IBD
Severity Assessed by?
True love witts criteria..
1.>or equal 6 bloody stool/24hr
Plus one or more
-Fever
-Anemia
-Tachycardia
-raised inflammatory markers
182
#IBD
toxic megacolon,PSC and cholangiocarcinoma,adenocarcinoma are the complications of?
UC
183
#IBD
Which bacteria you will search during bacteriological inv?
Clostridium difficile
184
#IBD
Features Unrelated to the activity of IBD?
Autoimmune Hepatitis
PSC & cholangiocarcinoma
Gall stone & oxalate renal stone
Amyloidosi
Sacroilitis
Metabolic bone disease
185
#IBD
Extra intestinal features of IBD
A PIE SAC
Apthous ulcer
Pyoderma gangrinosum
Iritis,episcleritis,conjunctivitis
Erythema Nodosum
Sclerosing cholangitis
Arthritis
Clubbing
186
#IBD
Painful ulcer in shin + UC
Painful Nodule in shin+ UC
Pyoderma gangrinosum
EN
187
#IBD
Pyoderma & EN are associated with Active disease..T/F?
T
188
#IBD
Drugs for remission induction?
Aminosalisylates & steroid
189
#IBD
Drug for maintenance?
Antimetabolites(Azathioprine,mercapturine,MTx)
190
#IBD
Severe ulcerative colitis refractory to steroid?
Ciclosporin
191
#IBD
Mtx has important role in UC maintenance?T/F
F... No role
192
#IBD
Maintenance therapy for CD?
Thiopurines
(Azathiprines & mercapturine)
193
#IBD
In pregnancy which drug must be avoided?
Mtx (6 months prior)
Tofacitinib
194
#IBD
CD is associated with which type of diet?
Low residue,high refined sugar
