GIT Summary Flashcards
Pathophysiology of Celiac disease, Also genetic Associations
Autoimmune mediated intolerance to gliadin leading to malabsorption
Histological findings of celiac disease
Crypt hyperplasia and blunted villi
Serum diagnosis of Celiac
The presence of Tranglutamase in serum
Crohns disease Cause
Abnormal responce to normal gastro flora
Signs of Crohns disease
Increased bowel wall thickness along with stricture formation and diarrhoea (possibly bloody)
Treatment for Crohns disease
Corticosteroids and resection of bowel
Ulcrative colitis cause
Autoimmune
Symptoms of Ulcerative coloits
Colon inflammation, mucosal and submucosal inflammation and crypt abcesses
IBS symptoms
Pain that improves with bowel movement along with a change in stool appearence
Cause of Adhesions
Common post op, or infalmmation/ infection
Order of common places of Colorectal cancer
Sigmoid> Ascending> Descending
What causes Cirrhosis
Diffse fibrous and nodular regeneration cuasing abnormal architeture
Common places of portosystemic shunts in Cirrhosis
Umbilical and eosophageal
Serum markers in Viral Hep
ALT>AST
Serum Markers in Alcholic Hep
ALT<AST
What is Elevated ALP a sign off?
Obstructive hepatobiliary disease (biliary involvement in disease)
What is an increased uncojugated bilirubin a sign of?
Hemolytic anaemia
Often seen in new borns
What is an increased conjugated Bilirubin a sign of?
Biliary obstruction and or biliary disease
What is an increase mixed bilirubin sign of?
Cirrohisis and Hep
Use and name of H2 antagonists
RanitiDINE, used in gastric ulcers and milkd GERD as it reduced H+ release
Use and name of proton pump inhibitors
OmePRAZOLE
Increases the pH of the stomach through the inhibition of proton pumps
