Glaucoma Drugs

Question 1

Netarsudil MOA?

Answer 1

Rho kinase inhibitor

Question 2

Netarsudil s/e?

Answer 2

Deposit over cornea - cornea verticillata

Question 3

Ace i metabolism by?

Answer 3

Kidney

Question 4

Ace i metabolized by liver

Answer 4

Fosinopril and moxepril

Question 5

Lipid soluble beta blockers

Answer 5

LMP
LABETOLOL
METAPROLO
PROPRANOLOL

Question 6

T type CCB receptors present in?

Answer 6

Nerves

Question 7

Non specific CCB?

Answer 7

Verapamil

Question 8

Anal fissures which ointment is used?

Answer 8

Verapamil+ligno
Diltiazem
NTG

Question 9

Diltiazem s/e?

Answer 9

Gum hypertrophy
Heart block
Constipation
Headache

Question 10

Doc for htn crisis
Mxtx of htn
Vasospastic angina

Answer 10

Dihydropyridine

Question 11

Doc for sub arachnoid hemorrhage

Answer 11

Dihydropyridine

Question 12

Captopril fast or slow action?

Answer 12

Fast.

Capto and lisinopril are fast action drugs

Question 13

Beta blockers with lipid solubility?

Answer 13

LMP
LABETOLOL
METAPROLOL
Propanol

Question 14

Non lipid soluble/kidney elimination beta blockers?

Answer 14

ANS
atenolol
Nadolol
Sotalol

Question 15

Nifedipin s/e

Answer 15

Gum hypertrophy

Question 16

sodium nitroprusside acts on?

Answer 16

both arterioles and venules

Question 17

sodium nitroprusside s/e?

Answer 17

cyanhemoglobin, NaI blockade=hypothyroidism

Question 18

hypertensive emergency?

Answer 18

more than 180/110 with end organ damage

Question 19

Nitric oxide iducer CCB?

Answer 19

hydralazine

Question 20

NTG acts on?

Answer 20

Venodialtor>arterio (MOA: venous pooling- reduced return- reduced preload and stretching

Question 21

dose of ntg?

Answer 21

0.3 to 0.6mg sublingual

Question 22

steal phenomena?

Answer 22

Dipyridamole and isoflurane

Question 23

robinhood phenomena?

Answer 23

Beta blockers and Nitroglycerines (TIP: roBiNhood)

Question 24

to prevent tolerance for NTG what should be done?

Answer 24

8-10 hours gap- NITRATE FREE PERIOD

Question 25

Telmisartan special use?

Answer 25

in DM, to prevent renal scarring/sclerosis

Question 26

Losartan (ARB) action on plt and uric acid?

Answer 26

anticoag and uricosuric

Question 27

HTN crisis DOC?

Answer 27

NICARDIPIN

Question 28

all nitrates have high 1st pass met, hence not given orally. But, which nitrate is given orally only?

Answer 28

isosorbide mononitrate

Question 29

DOC for nitrate poisoning?

Answer 29

methylene blue

Question 30

trimetazidine moa?

Answer 30

pFOX inhibitor - partial fatty acid oxidn

Question 31

Morphine indicated in which cardiac condition?

Answer 31

2nd doc in pulm edema after furesemide

Question 32

name some inodilators and its indications?

Answer 32

Amrinone, milri, levosimendon. Inotropic action and dialtor action. Thus, used in CHF e pulm htn.