Glomerular Nephrotic Syndromes of the Kidney

Question 1

Most common cause of proteinuric renal disease in kids

Nephrotic Proteinuria (>3) and symptoms (hypoalbumineia, edema, hyperlimidemia, fat bodies in urine); sudden onset

Tx: Corticosteroids

Answer 1

Minimal Change Disease

Question 2

Common, due to primary renal disease or secondary to heroin use, obesity, AIDS, urinary reflux

Proteinuria; decreased GFR, marked edema

Biopsy

Tx: Steroids, symptomatic

Answer 2

Focal Segmental Glomerulonephritis