Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Renal > Glomerulonephritis > Flashcards

Glomerulonephritis Flashcards

(52 cards)

Start Studying
1
Q

Polysystemic cause of GN with involvement of lungs skin, sinuses and kidneys

A

Wegener’s granulomatosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Initial test for Wegener’s

A

C-ANCA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Diagnostic Test for Wegener’s and what is seen

A

Renal Biopsy - granulomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Treatment of Wegener’s

A

Cyclophosphamide + Steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Wegener’s with asthma

A

Churg-Strauss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Initial test of Churg Strauss

A

P-ANCA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Diagnostic test of churg strauss + what is seen

A

lung biopsy - granulomas, eosinophils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Treatment of Churg Strauss

A

cyclophosphamide + steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Organs involved in Goodpasture’s Syndrome

A

Renal and lung ONLY

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Initial test of Goodpastures

A

anti-GBM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Diagnostic test of goodpastures

A

renal/lung biopsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Treatment of Goodpastures

A

plasmapheresis + streoids (may add cyclophosphamide)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

GN associated with Hep B, postprandial abdo pain, stenosis and aneurysms

A

polyarteritis nodosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

diagnostic test in polyarteritis nodosa

A

sural nerve biopsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

polyarteritis nodosa treatment

A

cyclophosphamide + steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

GN associated with haemolytic anaemia, thrombocytopaenia, schistocytes and E.coli:H7 infection

A

TTP/HUS
TTP – thrombotic thrombocytopaenic purpura
HUS – haemolytic-uremic syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

TTP/HUS initial test (two possible)

A

FBC/smear

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

TTP/HUS treatment (not severe)

A

fresh frozen plasma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

TTP/HUS treatment (severe)

A

plasmapheresis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

GN in longstanding diabetes and hypertention

A

Diabetic nephritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Treatment of diabetic nephritis

Study These Flashcards
A

diabetes management with ACE or ARB

22
Q

Second most common cause of nephrotic disease in adults

Study These Flashcards
A

Membranous GN

23
Q

Test for membranous GN and what is seen

Study These Flashcards
A

renal biopsy - subepithelial IgG deposits in BM

24
Q

Membranous GN treatment

Study These Flashcards
A

steroids, alkylating agents, B cell monoclonal Ab, manage hypertension with ACE/ARB, diuretics, low salt dier

25
GN associated with multiple myeloma or chronic inflammation
Amyloidosis
26
Amyloidosis diagnostic test and what is seen
renal biopsy - congo red "apple green birefringence"
27
GN associated with deafness
Alport's Syndrome
28
GN associated with malar rash, joint/skin involvement
SLE
29
Initial tests in SLE (two)
anti-dsDNA, anti-sm
30
Diagnostic test of GN in SLE (sometimes, if clinical picture isn't clear)
renal biopsy
31
SLE GN treatment
steroids + mycophenolate
32
Commonest GN in the world, 1-2 days post infection with macrohaematuria and proteinuria
IgA-mediated nephropathy
33
Other name for IgA-mediated nephropathy
Berger's disease
34
Diagnostic test for IgA-mediated nephropathy and what it shows
Renal biopsy - IgA deposition in mesangium on IF
35
Treatment of IgA-mediated nehropathy
ACE/ARB or fish oil
36
IgA-mediated nephropathy - how many progress to end stage
~1/4
37
Most common GN in paeds
Minimal Change
38
Minimal change diagnostic test + what is seen
Renal biopsy on electron microscopy - fusion of foot processes
39
Minimal change treatment
Supportive - Ace inhibitors, steroids, cyclophosphamide if resistant
40
When does minimal change disease normally resolve
3 months
41
GN 1-2 weeks post (usually) throat infection
post-streptococcal glomerularnephritis
42
Initial test in PSGN
ASO
43
Diagnostic test in PSGN
renal biopsy (IgG and complement deposition)
44
PSGN treatment
supportive
45
nephrotic GN in young patients associated with hep
Membrano-proliferative GN
46
Membrano-proliferative GN diagnostic test + what is seen
Renal biopsy - IgG deposits
47
Membrano-proliferative GN treatment
dipyridamole, aspirin, IFN-alpha, ribavirin
48
Membranoproliferative GN will progress to end stage renal disease - true/false
TRUE
49
Commonest cause of nephrotic syndrome in adults, large amounts of waxy casts, assoc with HIV and obesity
FSGS
50
FSGS diagnostic test
renal biopsy
51
FSGS treatment
prolonged steroids, ACE inhibitors, ARB, diuretic
52
FSGS will progress to end-stage renal disease - true/false
TRUE

Renal (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions