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GLOSSARY Flashcards

0
Q

An antibody produced in response to one antigen that will react with a second antigen genetically unrelated antigen.

A

HETEROPHIL ANTIBODY

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1
Q

A heterophil antibody that is stimulated by one antigen and reacts with unrelated surface antigen present on cells from different mammalian species

A

FORSSMAN ANTIBODY

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4
Q

An AGGLUTININ is an antigen that is capable of causing agglutination with surface antibodies. TRUE OR FALSE.

A

FALSE. Its an antibody.

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6
Q

The removal of antibodies from serum by the addition of red cells that possess the corresponding surface antigen.

A

ABSORPTION

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7
Q

Inflammation of the liver caused by a virus or other agent

A

HEPATITIS

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8
Q

In ABSORPTION, we remove antibodies from serum by adding what?

A

Red cells with the corresponding antigen

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9
Q

Immunity that is generated by the actual production of antibody by the host in the presence of foreign antigen

A

ACTIVE IMMUNITY

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11
Q

A system for activating complement beginning at C3 and do not involve a serologic reaction

A

ALTERNATIVE COMPLEMENT PATHWAY

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12
Q

The attachment of one substance to the surface of another, in particular, the attachment of antibody to specific receptors on a cell surface.

A

ADSORPTION

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14
Q

Anti-sheep red blood cell antibody that causes hemolysis of sheep red cells in the presence of complement

A

AMBOCEPTOR

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16
Q

A substance composed of extract from fresh beef hearts combined with lecithin and cholesterol

A

CARDIOLIPIN ANTIGEN

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17
Q

An antibody that is capable of causing agglutination with surface antigens

A

AGGLUTININ

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18
Q

A substance (usually injected with an antigen) that improves the immune response, either humoral or cellular, to the antigen

A

ADJUVANT

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20
Q

The special affinity between an antigen and its corresponding antibody

A

SPECIFICITY

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21
Q

BE antigen is a substance contained in beef erythrocytes, which is capable of absorbing the heterophil antibodies produced as a result of – and serum sickness.

A

INFECTIOUS MONONUCLEOSIS

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23
Q

A globulin formed in response to exposure to an antigen.

A

ANTIBODY(Ab)

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24
Q

Also known as immunoglobulin

A

ANTIBODY

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25
Q

Union of antibody with its homologous antigen

A

ANTIGEN-ANTIBODY COMPLEX

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26
Q

Flagellar antigens of bacteria

A

H ANTIGENS

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27
Q

How does an ADJUVANT increase the production of antibodies to, or the degree of sensitization against antigen?

A

By increasing its size or length of survival in the circulation

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28
Q

An autoantibody directed against a component of the nucleus, commonly found in systematic lupus erythematosus

A

ANTINUCLER ANTIBODY (ANA)

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29
Q

A lymphocyte from the bursa of Fabricius or an immunoglobulin-forming cell

A

B-cell

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31
Q

A protein, not normally present in human blood, appears in a wide variety of inflammatory conditions. It is characterized by their ability to react with the C-polysaccharide somatic substance of the pneumococci

A

C-REACTIVE PROTEIN

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34
Q

Normal serum constituents that increase in the presence of infection, injury or trauma to the tissues.

A

ACUTE PHASE PROTEINS

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35
A serum containing antibody
ANTISERUM
36
An antibody produced against streptolysin O
ANTISTREPTOLYSIN O (ASO)
37
C-REACTIVE PROTEIN is characterized by their ability to react with the -- substance of the pneumococci
C-polysaccharide somatic substance
38
A hemolysin produced by Group A streptococci
Streptolysin O
39
A substance contained in beef erythrocytes, which is capable of absorbing the heterophil antibodies produced as a result of infectious mononucleosis (IM) and serum sickness
BEEF ERYTHROCYTE ANTIGEN
40
The major system of complement activation that involves all nine components of complement and is initiated by a serologic reaction
CLASSIC COMPLEMENT PATHWAY
41
A molecule that behaves as a "self" antigen
AUTOANTIGEN
42
A humoral mechanism of nonspecific immune response consisting of at least 14 components that proceed in a cascading sequence of activation resulting in cell lysis
COMPLEMENT
43
The fixation or binding of complement in a reaction with antigen and antibody
COMPLEMENT FIXATION
44
Enzyme immunoassay is a ligand assay in which the label is -- and the binding reagent is --.
LABEL = ENZYME; BINDING REAGENT = ANTIBODY
47
The failure of a serologic reaction to occur in high concentration of antibody
PROZONE REACTION
48
An antibody capable of causing the lysis or dissolution of red cells with the consequent release of hemoglin
HEMOLYSIN
49
An assay in which one of the reactants is bound to a surface
SOLID RADIOIMMUNOASSAY
50
Cardiolipin antigen is a substance composed of extract from fresh beef hearts combined with what? Name two.
LECITHIN AND CHOLESTEROL
51
The surface somatic antigen of bacteria
O ANTIGEN
52
A hemagglutination test that defines the characteristics of heterophil antibody by guinea pig and beef cell antigens
DAVIDSOHN DIFFERENTIAL TEST
53
The most common procedure for the separation of mononuclear cells.
DENSITY GRADIENT CENTRIFUGATION
54
Monitors day to day accurate performance of the laboratory tests/analyses
CONTROL
55
Density gradient centrifugation is the most common procedure for the separation of what kind of cells?
MONONUCLEAR CELLS
56
An antigen that is not genetically determined and is sometimes transient
ACQUIRED ANTIGEN
57
The separation of one substance from the other.
DISSOCIATION
59
An antigen agglutinated or clumped by an agglutinin
AGGLUTINOGEN
60
A fluid medium containing antibodies deliberately removed from the red cells.
ELUATE
62
A specific type of precipitation that occurs over a narrow range of antigen concentration
FLOCCULATION
63
It is found in varying small amounts normally, but is usually increased in syphilis, malaria and certain other diseases.
REAGIN
64
The agglutination or clumping of red blood cellls by the antiserum
HEMAGGLUTINATION
65
An enzyme that dissolves clots by converting plasminogen to plasmin
STREPTOKINASE
66
Ruptured erythrocytes
HEMOLYZED
67
A substance which absorbs the Forssman and serum sickness antibodies.
GUINEA PIG KIDNEY ANTIGEN
68
Virus that caused AIDS
Human Immunodeficiency Virus
69
A solution that has a concentration greater than the system with which it is compared
HYPERTONIC SOLUTION
70
A branch of biology which concerns itself with antigens and antibodies and their relationships
SEROLOGY
71
The agglutination of red blood cells by a virus
VIRAL HEMAGGLUTINATION
72
A process by which the activity of serum complement is nullified
INACTIVATION
73
Aggregation of colloidal particles in a serologic reaction
FLOCCULATION
74
An acute infectious disease caused by Epstein-Barr virus characterized by fever, pharyngitis and lymphadenopathy. There is moderate leukocytosis due to abnormal mononuclear cells.
INFECTIOUS MONONUCLEOSIS
76
An antigen-antibody reaction in which a soluble antigen is caused to settle out by the action of specific antibody
PRECIPITATION
77
A thymus derived lymphocyte responsible for cell-mediated hypersensitivity
T-LYMPHOCYTE
78
The creation of a stable preparation of a biologic material by rapid freezing and dehydration of the frozen product under high vacuum
LYOPHILIZATION
79
The reduction in the electrical charge of a red cell when it is suspended in a high ionic strength colloidal medium
ZETA POTENTIAL
81
An antibody which causes dissolution or lysis of cells
LYSIN
82
An antibody that attaches to a cellular or particular antigen rendering it susceptible to phagocytosis
OSPONIN
83
Hemagglutination resulting from antibodies that are directed against antigens absorbed to their erythrocyte surface
PASSIVE AGGLUTINATION
84
The liquid portion of unclotted blood
PLASMA
85
A weak or irregular antigen-antibody reaction occurring when a great excess of antigen is exposed to a serum containing a relatively low titer of antibody
POSTZONE REACTION
86
A negative or weak reaction occurring when serum containing an extremely high titer of antibody is exposed to a relatively small amount of antigen.
PROZONE REACTION
88
The clumping of cells caused by agents other than antibodies
PSEUDOAGGLUTINATION
90
An atom with an unstable nucleus that spontaneously emits radiatin as it decays to a stable nucleus
RADIOISOTOPE
91
A progressively higher dissolution of a substance arranged in a definite sequence or series
SERIAL DILUTION
92
T-CELL is a thymus derived lymphocyte responsible for what kind of hypersensitivity?
CELL-MEDIATED
93
Streptokinase dissolves clots by converting -- to --
PLASMINOGEN TO PLASMIN
94
An expression of the highest dilution of serum which gives a visible reaction
TITER
95
An antibody (or agglutinin) or hemagglutinin that is active at 37 degrees but not 4 degrees celcius
WARM AGGLUTININ
96
The measurement of light transmitted through a suspension of particles
TURBIDIMETRY
97
A condition wherein the cells are coated with incomplete (blocking or univalent) specific antibody
SENSITIZED
98
The detection of a specific antibody in the serum of an individual in whom the antibody was previously undetectable
SEROCONVERSION
99
The fluid portion after the blood clots
SERUM
100
An antibody-like substance produced by the body in response to certain types of tissue invasion and destruction
REAGIN
102
Any substance which, when introduced into the body stimulates the formation of antibody
ANTIGEN (Ag)
103
A ligand assay in which the label is an enzyme and the binding reagent is an antibody.
ENZYME IMMUNOASSAY
104
A substance in the blood and the lymph serving as one of the active component on the process of cytolysis, the other components being the complement and the cells with antibodies.
AMBOCEPTOR
113
Substance that can increase the specific antibody production to, or the degree of sensitization against antigen by increasing its size or length of survival in the circulation.
ADJUVANT
114
An antibody produced against "self" antigen
AUTOANTIBODY
115
An agglutinin or hemagglutinin that is active at 4 degrees C but not at 37
COLD AGGLUTININ
117
Collection into clumps of the cells or particles distributed in a fluid.
AGGLUTINATION
119
Used in the detection of antibodies involved in the blocking of agglutination of erythrocytes
HEMAGGLUTINATION-INHIBITION TECHNIQUE
122
A substance causing the agglutination of red blood cells
HEMAGGLUTININ
124
An antigen-antibody reaction in which the reactive effect of a particular antigen is nullified by a specific antibody
NEUTRALIZATION
125
The dilution point in a serologic reaction in which all the antigen and all the antibody are mutually involved in complexes.
EQUIVALENCE POINT
126
A molecule that combines with specific complementary configurations of the binding agent
LIGAND
127
An antigen that is broadly distributed in nature
HETEROPHIL ANTIGEN
129
Any substance that oppose or counteract the action of a complement
ANTICOMPLEMENTARY SUBSTANCE
134
Antinuclear antibody is an autoantibody directed against a component of the nucleus commonly found where?
In SYSTEMATIC LUPUS ERYTHEMATOSUS (SLE)

SEROLOGY IMMUNOLOGY (1 decks)

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