Glycogenesis

Question 1

What is glycogenesis

Answer 1

This is the formation of glycogen from glucose molecules

Question 2

What is the first step in glycogenesis?

Answer 2

The first step in glycogenesis is the creation of UDP-glucose. Glucose -1-phosphate is paired with a nucleotide unit that has Uracil as its base (UDP) and UPD-glucose phosphorylase will produce UDP-glucose and pyrophosphate (PPi).

Question 3

What is the second step in glycogenesis?

Answer 3

glycogen synthesis. In this step, the enzyme glycogen synthase will add the UDP-glucose to the non-reducing end of a glycogen chain, which also releases the UDP. This step costs about 1ATP for each glucose added

Question 4

What is the third step in glycogenesis?

Answer 4

the glycogen branching enzyme. This enzyme will create new branches along the glycogen chain. It does this by catalysing the transfer of a block of 6 or 7 glucose residues from the non-reducing end of a glycogen chain (Containing at least 11 residues).

Question 5

What is glycogenin used for?

Answer 5

Glycogen synthase cannot initiate synthesis - Glycogenin is both the primer on which new chains are synthesised, and the enzyme that catalyses their assembly