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Flashcards in GN 6 1AMNR Deck (30)
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1

First sign of puberty in females

breast budding

2

Latest sign of puberty in females

menarche

3

Arrange the ff in order:
a. Breast budding
b. Menarche
c. Pubic hair
d. Growth Spurt

A-C-D-B

4

absence of menstrual bleeding is defined as

Amenorrhea

5

Condition caused by anatomic disorders interfering with the outflow o menses, such as an imperforate hymen or trasverse vaginal septum, although these women are menstruating.

Cryptomenorrhea

6

The following need Gynecologic evaluation EXCEPT
a. a 13 year old girl with no breast development/breast budding
b. a 15 year old girl who have not menstruated
c. a 14 year old girl with breast budding but no menses
d. NOTA, all should be evaluated

C;

7

This is defined as the absence of menses for an arbitrary period, usually longer than 6-12 months in a woman who previously had menstruation.

Secondary amenorrhea

8

low estrogen, low FSH, low PRL, no CNS lesion
a. WHO type I
b. WHO type II
c. WHO type III
d. WHO type IV

A

9

normal estrogen, normal FSH, normal PRL,
a. WHO type I
b. WHO type II
c. WHO type III
d. WHO type IV

B

10

low estrogen, high FSH
a. WHO type I
b. WHO type II
c. WHO type III
d. WHO type IV

C

11

Mean age of american girl in tanner stage B2

10-11 y.o

12

Mean age of american girl in tanner stage P2

11 y.o.

13

Mean age of american girl at onset of Menarche

12-13 y.o.

14

The following is least likely to have late menarche
a. 10 year old girl with anorexia bulimia
b. 10 year old world-competing gymnast
c. 10 year old overweight girl
d. 10 year old underweight girl

C

15

Girls engaged in premenarchial athletic training will be have delayed menarche by ____ for each year of training

0.4 year

16

Stress can delay onset of menarche by what mechanism?

Release of CRH -> ACTH -> cortisol
CRH inhibits GnRH

17

Hormone important for feedback involving GnRH and LH pulsatility and binds to specific receptor sites on the ovary and endometrium. This hormone is produced by adipocytes and correlates well with body weight

Leptin

18

This gastric peptide interacts with leptin when menstrual function is perturbed

Ghrelin

19

Patients with external and internal female features but karyotype is XY

Swyer syndrome

20

most common cause of primary amenorrhea

failure of gonadal development

21

Most common cause of gonadal failure

chromosomal disorder or deletion of all or part of X chromosome

22

Percentage of primary amenorrhea will have what cause?
a. Swyer syndrome
b. 17 alpha hydroxylase deficiency
c. constitutional delay
d. failure of gonadal development

D

23

Turner syndrome has the ff EXCEPT
a. breast development
b. uterus
c. primary amenorrhea
d. AOTA

A

24

True of pure gonadal dysgenesis
a. 45 XO
b. primary amenorrhea
c. breast development
d. gonadal development
e. No uterus

B.
45 XX
No breast development
d. gonadal development

25

Kallman's syndrome, 46XX
a. Absent breast development, uterus absent
b. With breast development, uterus absent
c. Absent breast development, uterus present
d. With breast developement, uterus present

C

26

Craniopharyngioma
a. Absent breast development, uterus absent
b. With breast development, uterus absent
c. Absent breast development, uterus present
d. With breast developement, uterus present

C

27

Androgen resistance
a. Absent breast development, uterus absent
b. With breast development, uterus absent
c. Absent breast development, uterus present
d. With breast developemnt, uterus present

B

28

17-a-hydroxylase deficiency with 46 XY karyotype
a. Absent breast development, uterus absent
b. With breast development, uterus absent
c. Absent breast development, uterus present
d. With breast developement, uterus present

A

29

2 conditions with breast development but uterus absent

Androgen resistance syndrome
Congenital absence of the uterus ( MRKH)

30

Second most frequent cause of primary amenorrhea

Mayer-Rokitansky-Kauster-Hauser syndrome