GN 6 1AMNR

Question 1

First sign of puberty in females

Answer 1

breast budding

Question 2

Latest sign of puberty in females

Answer 2

menarche

Question 3

Arrange the ff in order:

a. Breast budding
b. Menarche
c. Pubic hair
d. Growth Spurt

Answer 3

A-C-D-B

Question 4

absence of menstrual bleeding is defined as

Answer 4

Amenorrhea

Question 5

Condition caused by anatomic disorders interfering with the outflow o menses, such as an imperforate hymen or trasverse vaginal septum, although these women are menstruating.

Answer 5

Cryptomenorrhea

Question 6

The following need Gynecologic evaluation EXCEPT

a. a 13 year old girl with no breast development/breast budding
b. a 15 year old girl who have not menstruated
c. a 14 year old girl with breast budding but no menses
d. NOTA, all should be evaluated

Answer 6

C;

Question 7

This is defined as the absence of menses for an arbitrary period, usually longer than 6-12 months in a woman who previously had menstruation.

Answer 7

Secondary amenorrhea

Question 8

low estrogen, low FSH, low PRL, no CNS lesion

a. WHO type I
b. WHO type II
c. WHO type III
d. WHO type IV

Answer 8

A

Question 9

normal estrogen, normal FSH, normal PRL,

a. WHO type I
b. WHO type II
c. WHO type III
d. WHO type IV

Answer 9

B

Question 10

low estrogen, high FSH

a. WHO type I
b. WHO type II
c. WHO type III
d. WHO type IV

Answer 10

C

Question 11

Mean age of american girl in tanner stage B2

Answer 11

10-11 y.o

Question 12

Mean age of american girl in tanner stage P2

Answer 12

11 y.o.

Question 13

Mean age of american girl at onset of Menarche

Answer 13

12-13 y.o.

Question 14

The following is least likely to have late menarche

a. 10 year old girl with anorexia bulimia
b. 10 year old world-competing gymnast
c. 10 year old overweight girl
d. 10 year old underweight girl

Answer 14

C

Question 15

Girls engaged in premenarchial athletic training will be have delayed menarche by ____ for each year of training

Answer 15

0.4 year

Question 16

Stress can delay onset of menarche by what mechanism?

Answer 16

Release of CRH -> ACTH -> cortisol

CRH inhibits GnRH

Question 17

Hormone important for feedback involving GnRH and LH pulsatility and binds to specific receptor sites on the ovary and endometrium. This hormone is produced by adipocytes and correlates well with body weight

Answer 17

Leptin

Question 18

This gastric peptide interacts with leptin when menstrual function is perturbed

Answer 18

Ghrelin

Question 19

Patients with external and internal female features but karyotype is XY

Answer 19

Swyer syndrome

Question 20

most common cause of primary amenorrhea

Answer 20

failure of gonadal development

Question 21

Most common cause of gonadal failure

Answer 21

chromosomal disorder or deletion of all or part of X chromosome

Question 22

Percentage of primary amenorrhea will have what cause?

a. Swyer syndrome
b. 17 alpha hydroxylase deficiency
c. constitutional delay
d. failure of gonadal development

Answer 22

D

Question 23

Turner syndrome has the ff EXCEPT

a. breast development
b. uterus
c. primary amenorrhea
d. AOTA

Answer 23

A

Question 24

True of pure gonadal dysgenesis

a. 45 XO
b. primary amenorrhea
c. breast development
d. gonadal development
e. No uterus

Answer 24

B.
45 XX
No breast development
d. gonadal development

Question 25

Kallman's syndrome, 46XX a. Absent breast development, uterus absent b. With breast development, uterus absent c. Absent breast development, uterus present d. With breast developement, uterus present

Answer 25

C

Question 26

Craniopharyngioma a. Absent breast development, uterus absent b. With breast development, uterus absent c. Absent breast development, uterus present d. With breast developement, uterus present

Answer 26

C

Question 27

Androgen resistance a. Absent breast development, uterus absent b. With breast development, uterus absent c. Absent breast development, uterus present d. With breast developemnt, uterus present

Answer 27

B

Question 28

17-a-hydroxylase deficiency with 46 XY karyotype a. Absent breast development, uterus absent b. With breast development, uterus absent c. Absent breast development, uterus present d. With breast developement, uterus present

Answer 28

A

Question 29

2 conditions with breast development but uterus absent

Answer 29

Androgen resistance syndrome | Congenital absence of the uterus ( MRKH)

Question 30

Second most frequent cause of primary amenorrhea

Answer 30

Mayer-Rokitansky-Kauster-Hauser syndrome