Gonadal Sex, Ducts, External Genitalia

Question 1

Ovarian Development

Answer 1

XX cells in genital ridge secrete retinoic acid that causes PCGs to enter meiosis

Question 2

XX cells secrete:

Answer 2

RSPO1 and FOXL2

Question 3

Which duct develops in males?

Answer 3

Wolffian duct

Question 4

Which duct develops in females?

Answer 4

Mullerian duct

Question 5

What are the two secretion that cause male ductwork?

Answer 5

Androgens and anti-mullerian hormone

Question 6

How do Leydig cells effect the Wolffian ducts?

Answer 6

Leydig cells produce testosterone which is responsible for the development of the Wolffian ducts

Question 7

What are the androgens?

Answer 7

Testosterone
Dihydrotestosterone (DHT)
Dehydroepiandrosterone (DHEA)

Question 8

What are the estrogens?

Answer 8

Estradiol
Estriol
Estrone

Question 9

What does the Tfm locus do and where is it located?

Answer 9

Located on the X chromosome; puts testosterone receptors on the Wolffian duct

Question 10

How does DHT effect external genitalia?

Answer 10

If DHT is present, it will cause male external genitalia to develop