GORD Flashcards
(11 cards)
If GORD is left untreated, what can it lead to?
Oesophagitis Oesophageal stricture Barrett's Oesophagus Ulcers Iron Deficiency
What are the causes of GORD?
Hiatus hernia Oesophageal dysmobility LOS hypotension Obesity Gastric acid hypersecretion Delayed gastric emptying Smoking Alcohol Pregnancy Drugs (tricyclics, nitrates, anticholinergics) H Pylori
What are the symptoms of GORD?
Heartburn Burping Acid regurgitation Waterbrash (mouth fills with saliva) Odynophagia (painful swallow)
Noctural asthma
Laryngitis
Sinusitis
Chronic cough
What exacerbates/relieves heartburn?
Stooping
Lying
Straining
Post-meal
Antacids
What causes the odynophagia in GORD?
Oesophagitis
Ulcers
What are the histological changes in Barrett’s?
Squamous epithelium to columnar epithelium
metaplasia-dysplasia-neoplasia
What are the differentials of GORD?
Oesophagitis due to NSAIDS, herpes, candida Gatric/duodenal ulcer/cancer Cardiac pain Non-ulcer dyspepsia Oesophageal spasm
What tests do we do for GORD?
Endoscopy if dysphagia of +55 with ALARM
Manometry with 24hr pH
What are the ALARM Symptoms?
Anaemia Loss of weight Anorexia Recent onset Melaena Swallowing difficulty
What lifestyle changes should we recommend?
Weight loss Smoking cessation Small regular meals Eat +3hrs before bed Avoid alcohol, caffeine, spicy food, hot drinks, citrus fruits, tomatoes, onions, fizzy drinks, chocolate
Which drugs can we give for GORD?
Antacids 20mL/8hr
Alginate 10-20mL/8hr PO
PPI e.g lansoprazole 30mg/24hr
H2A - ranitidine 150mg BD