Gout

Question 1

Gout

Answer 1

Disruption in uric acid metabolism and deposits of urate salts in and around the joints

Question 2

Gouty Arthritis

Answer 2

Acute and painful inflammation of the joint, one or more. Urate crystals in the synovial fluid

Question 3

Chronic tophaceous gout

Answer 3

Advanced stage, many years after onset (around 10 years later)
Tophi

Question 4

What causes Gouty Arthritis

Answer 4

increased uric acid production, decreased uric acid excretion in kidneys or intake of foods containing purine. Two type primary and secondary-drug induced

Question 5

What would Gouty Arthritis look like?

Answer 5

Angry! intense pain, great toe, early in the morning
inflammation, edema, tenderness, redness
Fever, Malaise

Question 6

When does gouty arthritis peak and resolve

Answer 6

peaks 24-48 hrs and takes 5- 10 days for flare up to resolve

Question 7

how do we diagnose Gout

Answer 7

serum uric acid- elevated
24 hr urine
synovial fluid

Question 8

Where is Gout typically found

Answer 8

Great Toe

Question 9

Tophi are painful and filled with uric acid crystals?

True or False

Answer 9

False Tophi are painless and filled with uric acid crystals

Question 10

Primary Therapy for acute and chronic gout therapy

Answer 10

Drug therapy
Acute- Colchicine, relief in 2 day and NSAIDS
Chronic-Prophylactic- allopurinol- 2-6 weeks to see improvement

Question 11

Gout Collaborative Care

Answer 11

• address modifiable risk factors
• pain control & joint immobilization during flare up
• encourage fluids to maintain increase urine volume to prevent precipitation of uric acid in renal tubules

Question 12

modifiable risk factors for gout

Answer 12

Hyperuricemia
obesity
HTN
HLD
Ischemic cardiovascular disease
DM
CKD
Dietary factors
Alcohol
Medications altering urate balance