Group 1 - Furosemide (Lasix)

Question 1

Furosemide (Lasix)

Drug Class?

Answer 1

Furosemide (Lasix)

Drug Class: Loop Diruretic

Question 2

Furosemide (Lasix)

Mechanism of Action (MOA)?

Answer 2

Furosemide (Lasix) MOA:

• Inhibits electrolyte reabsorbtion in the ascending Loop of Henle.
• Promotes sodium, potassium, and chloride excretion.
• Vasodilation increases venous capacitance and decreases afterload.

Question 3

Furosemide (Lasix)

Indications?

Answer 3

Furosemide (Lasix) Indications:

Pulmonary edema, congestive heart failure

Question 4

Furosemide (Lasix)

Contraindications?

Answer 4

Furosemide (Lasix) Contraindications:

• Hypovolemia
• Hypotension
• Sensitivity to sulfonamides (sulfa drugs) - may induce allergic reaction

Question 5

Furosemide (Lasix)

Adverse Reactions?

Answer 5

Furosemide (Lasix) Adverse Reactions:

• Exacerbate hypovolemia
• Hyperglycemia
• Hypokalemia
• May decrease response to pressors

Question 6

Furosemide (Lasix)

Adult Dose?

Answer 6

Furosemide (Lasix) Adult Dose:

• If patient is on oral furosemide therapy:

Initial IV dose of 2X patient’s prescribed oral dose, if no effect in 20 minutes may double initial dose.

• If patient is NOT oral furosemide therapy:
  0. 5 - 1 mg/kg to a maximum of 2 mg/kg (usually 20 - 40 mg) IV slowly

Question 7

Furosemide (Lasix)

Pediatric Dose?

Answer 7

Furosemide (Lasix)

Pediatric Dose:

• 1 mg/kg IV slowly

Question 8

Furosemide (Lasix)

Onset?

Answer 8

Furosemide (Lasix) Onset:

5 minutes

Question 9

Furosemide (Lasix)

Peak Effects?

Answer 9

Furosemide (Lasix)

Peak Effects: 20 - 60 minutes

Question 10

Furosemide (Lasix)

Duration of Action?

Answer 10

Furosemide (Lasix)

Duration of Action: Variable

Question 11

Furosemide (Lasix)

AZ Drug Box Minimum Supply?

Answer 11

Furosemide (Lasix)

AZ Minimum Supply: Optional 100 mg

Question 12

Furosemide (Lasix)

Special Notes?

Answer 12

Furosemide (Lasix) Special Notes:

Ototoxicity and resulting deafness can occur