Growth and Development Flashcards

1
Q

How are maintenance fluids for a child calculated?

A

Per 24 hours:
First 10kg: 100ml/kg
Next 10kg: 50ml/kg
Subsequent: 20ml/kg

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2
Q

How many calories a day does a child need?

A

1000 + (100 x age)

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3
Q

State the gross motor milestones

A
3 months: hold head up
6-9 months: sits without support
13 months: walking
18 months: running
2: jump
3: ride a tricycle 
4: stand on one leg
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4
Q

What could cause a delay in gross motor milestones?

A

Cerebral palsy

Duchenne muscular dystrophy

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5
Q

State the fine motor and vision milestones

A
6 weeks: fixes and follows to 90 degrees
6-9 months: palmar grasp
10-12 months: pincer grip
18 months: 3 block tower
3: circle
4: square
5: triangle
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6
Q

What could cause a delay in fine motor and vision milestones?

A
  • cataract
  • retinoblastoma
  • albinism
  • retinopathy of prematurity
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7
Q

State the hearing and speech milestones

A
6-8 weeks: vocalise 
3 months: turn to sound
10-12 months: double syllable babble 
13 months: single words
2 years: 2 word sentences
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8
Q

What could cause a delay in hearing and speech milestones?

A
  • cleft lip and palate
  • autism
  • selective mutism
  • otitis media with effusion
  • ototoxic drugs
  • meningitis
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9
Q

State the social milestones

A
6 weeks: smile 
6-9 months: stranger awareness 
10-12 months: waves bye-bye 
3: interactive play 
4: can get dressed
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10
Q

What could cause a delay in social milestones?

A
  • autism
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11
Q

What are some differentials for delayed walking?

A
  • Cerebral palsy
  • Duchenne muscular dystrophy
  • Part of a syndrome of global delay
  • Maternal alcohol use
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12
Q

What can cause childhood deafness?

A
  • otitis media with effusion
  • ototoxic drugs
  • post meningitis
  • prematurity
  • down’s syndrome
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13
Q

How would you interpret height and weight centile charts? i.e. what is concerning?

A

A drop through the centiles is more concerning than always being in a low centile

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14
Q

How is a child’s target height calculated?

A

Boys:
Mid-parental height +/- 10cm
MPH = (M+F)/2 + 7

Girls:
Mid-parental height +/- 8.5cm
MPH = (M+F)/2 - 7

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15
Q

When would you consider that a child was failing to thrive?

A
  • Dropping centiles on their charts
  • Height less than target height
  • Low weight for height
  • No catch up from low birth weight
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16
Q

How much weight is it acceptable for a neonate to lose in the first few days? When should they regain it by?

A

10% for breast fed
5% for formulae fed

Catch up by 10-14 days

17
Q

What are some differentials for a child failing to thrive?

A

Reduced intake: infections, GORD, vomiting, inability to suck/swallow, neglect, picky eaters

Reduced absorption: CF, coeliac, inborn errors of metabolism

Increased metabolic demand: congenital heart disease, hyperthyroid, malignancy

18
Q

How is corrected age calculated?

A

Number of weeks old - number of weeks premature

19
Q

Define primary and secondary causes of short stature

A

Primary: condition intrinsic to the growth plate
Secondary: growth plate changes due to a condition

20
Q

What could cause a child to be of short stature?

a) primary
b) secondary

A

a) short parents, achondroplasia, Turners

b) Rickets, GH deficiency, hypothyroid, CF, coeliac

21
Q

How is short stature investigated?

A
Left hand x-ray 
Karyotyping for all girls (Turner's) 
TFTs
Vitamins inc calcium
FBC: anaemia of chronic disease
Growth hormone
22
Q

What hormonal change occurs at the beginning of puberty?

A

Increase in amplitude and frequency of GnRH pulses which activates the HPG axis

23
Q

What is the first sign of puberty in females?

A

Thelarche (breast development)

24
Q

What is the first sign of puberty in males?

A

Testis enlargement

25
What is adrenarche?
Development of pubic hair
26
When is a child considered a) overweight b) obese
a) >85th centile | b) >95th centile
27
When does puberty start in a) girls b) boys
a) 8-14 | b) 9-15
28
How is puberty staged?
Tanner staging
29
What are the types of pre-cocious puberty? What blood results would you expect in each?
``` Gonadotrophin dependant (central) - Raised LH and FSH ``` ``` Gonadotrophin independent (pseudo) - Low LH and FSH (due to -ve feedback) ```
30
State some causes of precocious puberty in boys
Central lesion such as astrocytoma Adrenal hyperplasia or tumour Testicular tumour Exogenous testosterone
31
What is the most common cause of precocious puberty in girls?
Normal as ovaries are very sensitive to gonadotrophins
32
When would you suspect a pathological cause of precocious puberty in girls? What could the cause be?
``` Occurs very fast Neurological symptoms (CNS tumour) Dissonance (ovarian tumour) ```
33
What is the role of growth hormone in precocious puberty?
Help child reach potential height before closure of the growth plates
34
When is puberty considered delayed?
Absence of testis enlargement by 14 Absence of thelarche by 13 Onset of puberty but no menarche by 15
35
What are the types of delayed puberty? What blood results would you expect with each?
Hypogonadotrophic hypogonadism - Low LH and FSH Hypergonadotrophic hypogonadism - High LH and FSH
36
What are some causes of hypogonadotrophic hypogonadism?
- Malnutrition/ over exercising - Chronic illness eg CF - Hypothyroidism - Hyperprolactinaemia - Kallmann syndrome
37
What are some causes of hypergonadotrophic hypogonadism?
Congenital - Prader-Willi, Turners, Kleinfelters Acquired - torsion, mumps, radiation
38
How is delayed puberty investigated?
``` Early morning serum LH and FSH TFTs Serum prolactin USS pelvis/ testis Genetic testing ```
39
What symptoms is associated with Kallman syndrome?
loss of smell