GU Infections Quiz

Question 1

What is the most common causative pathogen of genitourinary infections?

A) Pseudomonas aeroginosa
B) Enterococcus faecalis
C) Escherichia coli
D) Staphylococcus aureus

Answer 1

C

Question 2

Which of the following would NOT be an appropriate empirical regimen to start for a 52 year old female with no known past medical history who presents with complaints of dysuria and frequency that began 2 days ago?

A) Nitrofurantoin 100mg BID x 5 days
B) Amoxicillin 500 mg BID x 7 days
C) Sulfamethoxazole/trimethoprim 800/160 mg BID x3 days
D) Fosfomycin 3g x 1 dose

Answer 2

B - pt most likely has acute cystitis and MC organism is E coli which is gram negative, amoxicillin covers gram positive bugs

Question 3

Match the antimicrobial to the appropriate mechanism of action

Levofloxacin

Inhibits bacterial DNA synthesis through DNA gyrase/topoisomerase inhibition
Inhibits bacterial cell wall synthesis
Bacteria reduce to a reactive compound that inactivates or alters bacterial ribosomal compounds
Folate antagonist to inhibit bacterial DNA synthesis

Answer 3

Levo - inhbits bacterial DNA synthesis through DNA gyrase/topoisomerase inhibition

Question 4

Match the MOA:

Fosfomycin

Inhibits bacterial DNA synthesis through DNA gyrase/topoisomerase inhibition
Inhibits bacterial cell wall synthesis
Bacteria reduce to a reactive compound that inactivates or alters bacterial ribosomal compounds
Folate antagonist to inhibit bacterial DNA synthesis

Answer 4

Inhibits bacterial cell wall synthesis

Question 5

Match the MOA:

Bactrim

Inhibits bacterial DNA synthesis through DNA gyrase/topoisomerase inhibition
Inhibits bacterial cell wall synthesis
Bacteria reduce to a reactive compound that inactivates or alters bacterial ribosomal compounds
Folate antagonist to inhibit bacterial DNA synthesis

Answer 5

Folate antagonist to inhibit bacterial DNA synthesis

Question 6

Match the MOA:

Macrobid

Inhibits bacterial DNA synthesis through DNA gyrase/topoisomerase inhibition
Inhibits bacterial cell wall synthesis
Bacteria reduce to a reactive compound that inactivates or alters bacterial ribosomal compounds
Folate antagonist to inhibit bacterial DNA synthesis

Answer 6

Bacteria reduce to a reactive compound that inactivates or alters bacterial ribosomal compounds

Question 7

Match the MOA:

Amoxi clav

Inhibits bacterial DNA synthesis through DNA gyrase/topoisomerase inhibition
Inhibits bacterial cell wall synthesis
Bacteria reduce to a reactive compound that inactivates or alters bacterial ribosomal compounds
Folate antagonist to inhibit bacterial DNA synthesis

Answer 7

inhibits bacterial cell wall synthesis

Question 8

Your patient today needs to be treated for a serious infection, however this patient also has chronic renal failure. Which class of antibiotics would be the least likely to cause additional damage to the kidney?

A) Aminoglycosides
B) Cephalopsorins
C) Vancomycin

Answer 8

B