Guillain-Barré syndrome Flashcards
1
Q
What is GBS?
A
inflammatory demyelinating ascending polyneuropathy affecting PNS Schwann cells, typically after GI or respiratory infection
2
Q
What causes GBS?
A
campylobacter jejuni, cytomegalovirus, mycoplasma
3
Q
How does GBS present?
A
ascending muscle weakness, paraesthesia, lost reflexes, autonomic features (sweating, raised pulse, BP change), neuropathic pain
4
Q
How to diagnose GBS?
A
NCS (reduced signal), lumbar puncture (raised protein in CSF)
5
Q
How to manage GBS?
A
IV immunoglobulins, plasma exchange
