GUILLAIN BARRE SYNDROME

Question 1

Guillain-Barré syndrome (GBS), also known as

Answer 1

Acute Idiopathic Polyneuritis

Question 2

Signs and Symptoms

Answer 2

Muscle weakness that usually starts in the legs and spreads to the arms and upper body
Tingling or pricking sensations in the feet and hands
Loss of reflexes
Difficulty walking or moving the face
Fatigue
Difficulty breathing
Loss of sensation (paresthesia)
Body paralysis

Question 3

Predisposing factors:

Answer 3

Gastrointestinal infection
Trauma/surgery
Flu
Bacteria

Question 4

Diseases that can mimic GBS with the same signs and symptoms.

Answer 4

Brainstem stroke
Myasthenia gravis
Botulism
infective or inflammatory rhombencephalitis and bacterial
carcinomatous or lymphomatous meningitis.

Question 5

Diagnostic test for GBS:

Answer 5

History taking
Lumbar puncture
Electromyography

Question 6

Types:

Answer 6

-Acute Inflammatory Demyelinating Polyneuropathy
-Miller Fisher Syndrome
-Acute Motor Axonal Neuropathy
-Acute Motor Sensory Axonal Neuropathy

Question 7

IVIG works by modulating the immune response, reducing inflammation, and potentially blocking the harmful antibodies that are attacking the nerves.

Answer 7

Intravenous Immunoglobulin

Question 8

also known as plasma exchange, is a process for removing dangerous antibodies from the bloodstream. It entails separating the patient’s blood cells from the plasma, which includes the antibodies that trigger the immune system to attack the neurons. The plasma is subsequently replaced by a donor or synthetic plasma replacement.

Answer 8

Plasmapheresis