GYN Flashcards
(212 cards)
what days of cycle are optimal for fertilization
day 11-15
name the two phases (or 3)
follicular (proliferative)
luteal (secretory)
Follicular + menstruation
ovulation
luteal
Follicular phase
- days
- predominant hormone
day 1 (menstruation) to day 14 (ovulation) -new follicle is growing
HORMONES:
*GnRH–>FSH + LH–>follicle grows–>secreting estorgen–>provides (-) feedback to AP–>but then estrogen gets to a point where its very high and creates (+) feedback on FSH and LH—SURGE–. SURGE OF LH=OVULATION
what causes menstruation
progesterone withdrawal
what triggers ovulation
on day 11-14 a sugrge in LH occurs once dominant follicle is selected
corpus luteum
- progesterone production
- —-> neg feedback on FSH + LH
Luteal PHase
-hormone and its role
PROGESTERONE
- enhances endometrial lining to prepare it for implantation
- once there is no implantation– corpus luteum degenerates into corpus albicans —-> steep decr in estrogen + Progesterone
***this drop of hormones leads to menstruation and star of new cycle
MCC of secondary amenorrhea
pregnancy
ALWAYS DO PT IN EVERY PATIENT
primary vs secondary amenhorrhea
PRIMARY
- failure of menses to occur by age 15 (or 16) in presence of normal growth and secondary sexual characteristics
- ->start evaluation at age 13 if no menses + absence of secondary charactersistics
SECONDARY
*absence of menses for 3 MO in a woman with previous menses
oR
6 months in a woman with hx of irreg cycles
causes of primary amenorrhea
Turners syndrome—- XO
hypothalamic-pituitary insufficiency 46 XX
*low FSH low LH
Androgen insensitivity: 46 XY
High testosterone… breast development only
Imperforate hymen: 46, XX, diagnosed on PE
anorexia
mullerian agensis– no uterus but has secondary sex charactersitcs
Turners syndrome
XO
webbed neck, broad chest, high FSH
causes of secnoadry amenhorrhea
-what hormones to always check
pregnancy
hypothyroid
weight changes
prolactinoma
**ALWAYS CHECK BHCG, TSH and Prolactin
***progesterone challenege test–> medroxyprogesterone 5-10 mg PO once a day or another progesterone for 7-10 days—— if bleeding occurs=anouvulatory cycles
MCC of primary amenorrhea
GONADAL DYSGENSIS
- Turner syndrome– 45XO
- Mullerian dysgenesis– 46XX
- Androgen Insensitivity—46XY
a 35-year-old woman with concerns about heavy menstrual periods for the past year that occur at irregular intervals. She explains that sometimes her menses come twice a month but other times will skip two months in a row. Her menses may last 7 to 10 days and require 10 to 15 thick sanitary napkins on the heaviest days. PELVIC EXAM NORMAL NORMAL PAP no STIs
DUB
define DUB
excessive uterine bleeding with prolonged menses that is NOT CAUSED BY PREGNANCY OR MISCARRIAGE
**diagnosis of exlcusion
define Polymenorrhea
menses that occur more frequently (<21 days apart menses)
define hemorrhagic or hypermenorrhea
menses that involve more blood loss >7 days or >80 mL
menorrhagia
prolonged/heavy bleeding
>7 days or >80 ml at regular intervals
metrorrhagia
uterine bleeding that occurs frequently and irreguarly b/w cycles
menometrorrhaiga
more blood loss during menses and frequent and irregular bleeding b/w menses
oligomenorrhea
long intervals of >35 days
MCC of AUB/DUB
chronic anovulation
**corpus luteum does not form–>so noprogesterone formed—>unoppposed estrogen–>endometrial overgrowth–>irregular, unprediactable shedding
GS for diagnosis of AUB
uterine D/C
labs to order for DUB
bHCG
CBC, iron stuidies, PT, PTT,
TSH, progesterone, prolactin, FSH,
LFTs