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Flashcards in GYN cancers Deck (6)
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1
Q

Parp inhibitors approval in ovarian

A

olaparib 4th line therapy with BRCA mutation

2
Q

hereditary nonpolyposis colorectal cancer (HNPCC)

A

Women from hereditary nonpolyposis colorectal cancer (HNPCC) families have an increased risk of both endometrial cancer and ovarian cancer. There are a number of defined mutations in DNA mismatch repair genes associated with the HNPCC syndrome. Tumors associated with HNPCC typically show loss of mismatch repair protein expression on immunohistochemistry (IHC). Such a finding on IHC would prompt the need for genetic testing for HNPCC mutations.

3
Q

metastatic cervical cancer treatment

A

cis/taxol/bev

4
Q

cervical cancer <4cm

A

surgery and RPLND.

follow cis RT if high features

5
Q

cervical cancer>4cm

A

RT with cisplatin

6
Q

endometrial cancer stage 1A and 1B
2
3
4

A

1A watched (less than50% myometrium)
1B controversial IVRT +/-chemo
2 controversial
3 and 4 do carbo taxol dont add bev