Gynaecomastia Flashcards
1
Q
What is gynaecomastia?
A
abnormal amount of breast tissue in males
Usually caused by an increased oestrogen:androgen ratio
2
Q
List 8 causes of gynaecomastia
A
Physiological: normal in puberty
Syndromes with androgen deficiency: Kallman’s, Klinefelter’s
Testicular failure: e.g. mumps
Liver disease
Testicular cancer e.g. seminoma secreting hCG
Ectopic tumour secretion
Hyperthyroidism
Haemodialysis
3
Q
List 8 drugs that can cause gynaecomastia
A
Spironolactone (most common)
Cimetidine
Digoxin
Cannabis
Finasteride
GnRH agonists e.g. Goserelin, Buserelin
Oestrogens
Anabolic steroids
4
Q
List 6 very rare drug causes of gynaecomastia
A
TCAs
Isoniazid
CCBs
Heroin
Busulfan
Methyldopa
