Flashcards in Gynea cancer Deck (19):
How often are smears?
Cervical intraepithelial neoplasia (CIN) staging and follow-up
Which HPV risk for cervical cancer?
HPV 16 and 18
How frequently do people with HIV get smear tests?
Risk for endometrial cancer?
More oestrogen than progesterone
Endometrial cancer investigations
Signs of ovarian cancer?
Loss of appetite
Ca-125, family hx.
What are the main risk factors for endometrial cancer?
What cell type are the majority of cervical malignancies?
Squamous cell carcinoma
What's the most common type of ovarian cancer?
Serous cystadenocarcinoma (50%)
10% clear cell- poor prognosis
Which familial genes are associated with ovarian cancer?
Brca1 and 2. HNPCC.
What ovarian cancers do we see in children?
80% are germ cell tumours
Epithial tumours - teens
Sex-cord stromal tumours - <10yrs old (granulosa, theca cells)
What is Meigs syndrome?
Benign ovarian tumour (fibroma)
What are the stages for cervical cancer?
1a- limited to cervix - microscopic
2 - extension into uterus/parametrial/vagina
3 - extension to pelvic sidewall and or lower vagina
4 - extension beyond the true pelvis or involve the of bladder or bowel mucosa
What is the management for ovarian enlargement?
Pre menopausal - conservative if small cyst - monitor again in 8-12wks and then consider referral
Postmenopausal - refer to gyneacology
Post menopausal bleeding is assumed to be endometrial cancer, apart from in one case. When is it?
Only post- coital.
Suggests - polyp, vaginitis, foreign body
What are krukenberg ovarian tumours?
Mets from gastric tumours (histology shows signet ring cells)
What cells are seen in
A) granulosa cell tumours
B) brenner tumours
C) mucinous cystadenomae
D) fibromas (meigs)
A) call-exner bodies (follicles containing eosinophils)
B) transitional cells
C) endocervical cells
D) spindle shaped fibroblasts