H5 hormonaal stelsel Flashcards

1
Q

cortisone

A

systemisch cortico

anti-inflammatoir = mineralocorticoid

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2
Q

hydrocortisone

A

systemisch cortico
vaak bij bijnierschorsinsufficiëntie
anti-inflammatoir = mineralocorticoid

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3
Q

prednisolon

A

systemisch cortico

anti-inflammatoir > mineralocorticoid

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4
Q

methylprednisolon

A

systemisch cortico

anti-inflammatoir > mineralocorticoid

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5
Q

triamcinolon

A

systemisch cortico

anti-inflammatoir&raquo_space;

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6
Q

dexamethason

A

systemisch cortico

anti-inflammatoir&raquo_space;>

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7
Q

betamethason

A

systemisch cortico

anti-inflammatoir&raquo_space;>

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8
Q

insuline

A

bij type 1 DM en diabetes tijdens zwangerschap
type2 DM alleen na falen van orale AD of tijdelijk
hoog risico op hypo, gewichtstoename

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9
Q

insuline lispro, aspart, glulisine

A

ultrasnelwerkend insuline

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10
Q

metformine

A

1e keus bij DM type 2: verhoogt perifere insulinegevoeligheid en inhibeert glucosesynthese (lever)
gewichtsdaling en geen risico op hypo

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11
Q

glibenclamide, gliclazide, glimepiride, gliquidon, glipizide

A

hypoglycemiërende sulfamiden / sulfonylurea: stimuleren insulinesecretie
type 2 DM
niet bij nierinsufficiëntie
gewichtstoename en risico op hypo gemiddeld

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12
Q

repaglinide

A

gliniden: stimuleren insulinesecretie
type 2 DM
risico op hypo

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13
Q

pioglitazon

A

glitazonen (effect via PPAR-gamma)

type 2 DM

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14
Q

dulaglutide, Exenatide, Liraglutide, Lixisenatide, Semaglutide

A

incretinemimetica = GLP1 analogen
DM type 2
gewichtsdaling, geen risico op hypo

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15
Q

Alogliptine, Linagliptine, Saxagliptine, Sitagliptine, Vildagliptine

A

gliptines = DPP-4 inhibitoren
type 2 DM
geen risico op hypo

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16
Q

Canagliflozine, Dapagliflozine, Empagliflozine, Ertugliflozine

A

gliflozines = SGLT2 inhibitoren (verminderen glucose reabsorptie in nieren)
geen gewichtstoename, geen hypo risico, wel glucosurie

17
Q

Acarbose

A

inhibeert alfa-glucosidase

type 2 DM (weinig gebruikt)

18
Q

isofaan of NPH insuline

A

intermediair werkend insuline

19
Q

glargine, detemir, degludec

A

langwerkend insuline

20
Q

glucagon

A

IM of SC bij niet-bewuste patiënt met hypo

21
Q

levothyroxine

A

bij hypothyreoïdie (vaak door Hashimoto)

22
Q

thiamazol, propylthiouracil

A

thyreostaticum bij hyperthyreoïdie (Graves)
meestal block/replace methode
eerste weken soms + Beta blokker
replace = met levothyroxine