Flashcards in Haematology Deck (70)
When blood transfused why is it usually leukodepleted?
- To protect the recipient as this will reduce the risk of some infections and transfusion reactions.
Where is ABO gene found?
- It's an autosomal gene found on chromosome 9.
- A + B are dominant over O and A + B are co-dominant.
Which antibodies do people with blood groups A, B, AB and O produce?
- A produce anti B antibodies.
- B produce anti A antibodies.
- AB produce neither anti A or anti B antibodies.
- O produce both anti A and anti B antibodies.
Which blood type is the universal recipient and which is the universal donor?
- Universal donor: O.
- Universal recipient: AB.
What is blood?
- it's a multifunctional tissue.
- it's considered a form of fluid connective tissue as has the same embryonic origin as other connective tissues (mesodermal).
- it connects the body systems together (O2, nutrients, waste disposal etc.).
What is erythropoiesis?
- process which produces red blood cells.
How do platelets stop bleeding?
- at site of injury there will be damage and bleeding.
- vasoconstriction occurs.
- platelet adhesion and aggregate and form a plug.
- this activates a clotting cascade.
- regeneration of fibrin strands form a mesh amount platelets.
What is bone marrow?
- it's a flexible tissue in the anterior of bones.
- in humans red blood cells are produced by cores of bone marrow in the heads of long bones in a process known as haematopoesis.
- bone marrow is also a key component of the lymphatic system, producing the lymphocytes that support the bodies immune system.
What is the thymus?
- primary lymphoid organ of the immune system.
- with the thymus t lymphocytes (t-cells) mature.
- located in front of the heart and behind the sternum.
- composed of two identical lobes.
- thymus provides an inductive environment for development of T cells from hematopoetic progenitor cells.
- largest and most active during neonatal and pre-adolescent periods.