Haematology Definitions Flashcards

(92 cards)

1
Q

Hypo

A

low

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2
Q

Hyper

A

high

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3
Q

Cytic

A

small

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4
Q

Chromic

A

pale

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5
Q

Milo

A

bone marrow

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6
Q

Haem

A

blood related

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7
Q

Poesis

A

making

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8
Q

Erythopoeisis

A

making of red blood cells

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9
Q

Reticulocyte

A

red blood cells that are still developing

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10
Q

Reticulocytosis

A

a condition where there is an increase in reticulocytes, immature red blood cells.

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11
Q

Differentiation

A

the process by which dividing cells change their functional or phenotypical type

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12
Q

myeloproliferative disorder

A

increase in the number of myelocyte cells

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13
Q

haemolysis

A

when the immune system (which normally defends the body against infection) makes an antibody against its own red blood cells.

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14
Q

hypoxia

A

low levels of oxygen in body tissue

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15
Q

pancytopenia

A

condition in which there is lower than normal number of red and white blood cells and platelets in the blood

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16
Q

Hypochromic

A

pale RBCs

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17
Q

Normochromic

A

normal colour RBCs

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18
Q

Microcytic

A

small RBCs

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19
Q

Microcytosis

A

term used to describe microcytic RBCs

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20
Q

Pallor

A

colour

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21
Q

Haematocrit (Hct)

A

is the volume of red blood cells as a ratio of whole blood volume.

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22
Q

mean cell volume (MCV)

A

the average volume of each red cell

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23
Q

mean cell haemoglobin (MCH)

A

the average mass of Hb in each RBC

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24
Q

mean cell haemoglobin concentration (MCHC)

A

average concentration of Hb in each RBC

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25
Platelet count
the no of platelets in a given volume of blood
26
Anaemia
reduction in the amount of haemoglobin in a given volume of blood below what would be expected in comparison with a healthy subject of the same age and gender
27
G-CSF
granulocyte colony-stimulating factor
28
Target cell
red blood cells that have a shooting target appearance with a bullseye
29
Central pallor
pale colour found in the middle of RBCs due to their indentation
30
if a RBC lacks central pallor what is it a sign of
iron deficiency anaemia
31
Megaloblast
abnormally large red blood cells
32
Polychromasia
increased blue tinge to the cytoplasm of a red blood cell. Indicates cell is young
33
Mechanisms
physiological process that lead to the illness
34
Causes
the disease or injury that produces the physiological disruption
35
Full blood count (FBC)
type of blood test
36
Megaloblastic anaemia
macrocytic anaemia caused by vitamin B12 or folic acid deficiency
37
Haemolytic anaemia
reduction in Hb due to excessive haemolysis
38
Poikilocytosis
abnormally shaped red blood cells
39
Ferritin
blood protein that contains iron
40
Hepcidin
hormone responsible for regulation of iron recycling and iron balance
41
Transferrin
protein produced by liver that regulates absorption of iron into the blood
42
M-CSF
macrophage colony-stimulating factor;
43
GM-CSF
granulocyte-macrophage colony stimulating factor
44
Basophil
type of white blood cell, main function to defend against parasites or allergic reactions, initiating inflammation and preventing coagulation
45
intrathecal
around the spinal cord
46
proliferative disorder
uncontrolled increase in number of immune cells
47
splenomegaly
enlarged spleen
48
thrombocytopenia
low platelet count
49
megaloblastic anaemia
an anaemia in which maturation of the nucleus is retarded in relation to that of the cytoplasm
50
Neutrophil
type of white blood cell, main function is defence against infection through phagocytosis.
51
Eosinophil
type of immune cell that contains granules, with enzymes that are released during infections, allergic reactions and asthma
52
Microbicidal
agent that destroys microbes
53
Proliferation
increase in the no of cells as a result of cell growth and division
54
Chemotaxis
movement of cell in a direction corresponding to a gradient of increasing or decreasing concentration of a substance
55
Marginated
formation of a border
56
Adhere
stick to
57
Cytokine priming
release of cytokine leads to chemical gradient for WBCs to travel towards specific site
58
Heparin
type of anti-coagulant that decreases the clotting ability of the blood
59
Histamine
messenger molecule, released as part of local immune response
60
Proteolytic enzymes
enzymes that break down proteins
61
Leukocytes
white blood cells
62
Humoral immunity
...
63
Cell mediated immunity
...
64
Leukaemia
cancer of the white blood cells
65
Myeloid leukaemia
cancer of the myeloid cells
66
Lymphoid leukaemia
cancer of the lymphoid cells
67
acute conditions
severe and sudden in onset
68
chronic conditions
the disease and deterioration go on for a long period of time
69
aetiology
the cause or origin of disease
70
Haemopoesis
making of new blood
71
prognosis
likely outcome of the disease, chance of recovery or recurrence
72
Neutrophil hypersegmentation
increase in the average number of neutrophil lobes or segments
73
monocytosis
too many monocytes
74
Lymphopenia
reduction in lymphocyte count
75
Chronic
longstanding
76
Acute
recent
77
Lymphocytosis
too many lymphocytes
78
Persistent
continuing to exist over a long period
79
Non-segmented
not divided into or made up for segments
80
Toxic granulation
heavy coarse granulation of neutrophils
81
Band cell
immature form of neutrophils
82
Left shift
increase in non-segmented, immature neutrophils or there are neutrophil precursors in the blood, presence of immature neutrophils in blood
83
Toxic changes
...
84
Leukocytosis
increase in WBC no in the blood
85
Eosinophilia
increase in eosinophil numbers in the blood
86
Neutrophilia
increase in the no of neutrophils in blood
87
--cytosis
too many
88
--penia
to little/ reduction
89
lymphopenia
reduction in lymphocyte count
90
leukocytosis
too many white blood cells
91
leukopenia
reduction in the total number of RBCs
92
neutropenia
reduction in neutrophil count