Haematopoetic components Flashcards

(33 cards)

1
Q

where does erythropoiesis (red blood cell production) occur

A

bone marrow (pluripotent stem cells)

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2
Q

what do pluripotent stem cells develop to

A

Myeloid progenitor (become blood cells)
or
lymphoid progenitor (become lymphoid cells)

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3
Q

what is the function of erythrocytes

A

contain haemoglobin that bind to oxygen and carry it around the body.
and carry carbon dioxide for excretion

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4
Q

which cells produces platelets

A

megakaryocyte

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5
Q

what are reticulocytes

A

immature red blood cells

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6
Q

what are functions of neutrophils

A

tissue repair
phagocytic

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7
Q

which blood cell is not found in the blood

A

macrophages

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8
Q

how are macrophages developed

A

monocytes leave the blood and develop into macrophages in tissue

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9
Q

how to identify eosinophils under the microscope

A

very pink due to staining

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10
Q

function of eosinophils

A

helminth (soil transmitted) infection
allergy

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11
Q

most abundant white blood cells

A

neutrophils

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12
Q

how to identify monocytes

A

large nucleus
human kidney shape

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13
Q

how to identify basophils

A

large cytoplasmic granules that block the nucleus
not very abundant

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14
Q

what are the functions of mast cells

A

release histamines (activating factors) for wound release

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15
Q

what percentage of white blood cells are neutrophils

A

60%

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16
Q

what percentage of white blood cells are lymphocytes

17
Q

how to identify lymphocytes

A

very large nucleus
circular

18
Q

what is the adaptive immune system

A

specialised lymphocytes

19
Q

where are T lymphocytes developed

20
Q

where are B lymphocytes mature

A

Bone marrow and Lymph nodes
Bursa of Fabricus in birds

21
Q

What hormone stimulates erythrocyte production

A

erythropoietin

22
Q

which are the primary lymphoid organs

A

thumus
bone marrow (bursa of fabricius in birds)

23
Q

which are the secondary lymphoid organs

A

spleen
lymph nodes
tonsils

24
Q

what are tertiary lymphoid organs

A

ectopic tissue that develops at site of chronic inflammation

25
what are the lobules of the thymus
cortex medulla
26
when is the thymus most active
early life to make the most immune cells
27
what are the functions of the spleen
white pulp: surveys the blood that flows through for foreign antigens red pulp: filters + removes damaged or aged red blood cells by phagocytosis
28
what is the purpose of the spleen trabeculae
for contraction so spleen can push out erythrocytes
29
where are B cells localised in lymph nodes
follicles
30
what occurs in the paracortex of lymph nodes
T cells are localised
31
how to lymphocytes get from lymph nodes to the blood
efferent lymphatic
32
name the 5 palpable lymph nodes
submandibular pre scapula axillary inguinal popliteal
33
what is Gut Associated Lymphoid tissue
mucosal membrane that is exposed to the environment (secondary lymphoid tissue)