Haemoptysis/ Lung Ca Flashcards Preview

Transport > Haemoptysis/ Lung Ca > Flashcards

Flashcards in Haemoptysis/ Lung Ca Deck (34):
1

how can malignant primaries in the lung be classified

SMALL CELL (20-30%) - endocrine (kulchitsky cells)

NON-SMALL CELL
squamous
large cell
adenocarcinoma
bronchoalveolar

2

where else in the body are SCCs found

oesophagus, stomach and cervix

3

SCCs are endocrine cells which secrete polypeptides causing endocrine disturbance such as

Addison's
Cushings
Hypercalcaemia

4

why are SCCs often inoperable

early spread
respond well to chemo but poor prognosis

5

which electrolyte disturbance can be caused by lung squamous carcinoma

hypercalcaemia

6

which type of lung cancer cavitates with a jagged edge on CXR

squamous cell carcinoma

7

why does large cell lung cancer have a poor prognosis

metastasizes early

8

from which cells to lung adenocarcinomas develop

mucous cells in the bronchial epithelium causing excessive mucus production

9

which lymph nodes to adenocarcinomas spread to

mediastinal and pleural --> spreads to brain

10

which type of lung primary cancer can cause pleural effusions

adenocarcinoma

11

which lung primary cancer involves type II pneumocytes

bronchoalveolar
can cause bronchorrhoea and histologically tombstone/bobnail cells

12

in which demographic is lung adenocarcinoma more common in non-smokers

women
far east

13

whcih is the most common cause of cancer death

bronchial carcinoma

14

which type of lung cancer is particularly linked with smoking

squamous, small cell and large cell cancer

15

which type of asbestos is associated with mesothelioma

blue asbestos

16

what are paraneoplastic syndromes

non metastatic complications
HORMONAL:
- hyper calcaemia (squamous)
- SIADH
- ACTH

NEUROMUSCULAR
- lambert eaton myaesthenic syndrome
- cerebellar sydromes
- neuropathies

17

which way does the trachea deviate in pleural effusion caused by lung Ca

TOWARDS the tumour occluding the main bronchus

18

what is SVC obstruction

swelling of hands and face and arms
headaches worse when leaning forwards
dilated veins

19

wht are the signs of a Pancoast's tumour

rib destruction/pain in shoulder
atrophy of hand muscles in C8 T1 dist
Horner's syndrome (ptosis and small puplis)

20

progressive consolidation on CXR may be suggestive of which type of lung Ca

alveolar cell carcinoma

21

what is the DDx of consolidation on CXR

infection
water
blood
inflammation
tumour

22

what are the 4 Ts of anterior mediastinal masses

teratoma
thyroid
T cell lymphoma
Thymoma

23

which conditions is thymoma associated with

Myasthenia gravis
red cell aplasia
SLE
hypogammaglobinaemia
rheumatoid disease

24

what might be suggestive of lung Ca on CXR

peripheral circular opacities
hilar enlargement
lung collapse
consolidation
pleural effusion
bony secondaries

25

which derrangements might you see on blood tests in pts with lung Ca

hypercalcaemia from bone mets
hyponatraemia from Addisons
LFTs indicative of liver involvement
FBC - anaemia

26

which types of lung cancer is TNM staging used for

NSCLC

sCLC aggressive so categorised into limited or extensive

27

where might lung cancers spread directly

pleura and ribs
sympathetic ganglion -> Horners
Lt recurrent laryngeal nerve palsy -> hoarseness
Spinal cord compression
oesophagus
SVC obstruction

28

where do lung mets go to

bones
liver
brain
adrenal glands

29

what is carcinoid syndrome

hepatomegaly, flushing and diarrhoea

30

which type of lung cancer is surgery the main curative treatment for

NSCLC

31

what is the first line chemo agent for adenocarcinoma or large cell cancer of the lung

EGFR +ve
gefitinib or erlotinib

EGFR -ve
pemetrexed
paclitaxel

32

what is the first line chemo for squamous cell carcinoma of the lung

gemcitabine

33

what is the first line chemo for SCLC

carboplatin/ciplatin and etoposide

34

which two medical emergencies can lung Ca cause

spinal cord compression
SVCO
Hypercalcaemia