Hallucinogens

Question 1

What is the most common way people take acid?

Answer 1

Orally

Question 2

What is the half life of acid and the effect of onset?

Answer 2

3 hours; 45 minutes

Question 3

What is the effective and street dose of acid?

Answer 3

20 mg, 50-300 mg

Question 4

How long do the effects of acid last?

Answer 4

4-12 hours

Question 5

What are the major clinical manifestations?

Answer 5

Perceptual distortions and switched senses (hearing colors, seeing smells)

Question 6

What are two cool, good features of acid?

Answer 6

Euphoria and expanded consciousness

Question 7

What is the primary NT system involved in acid?

Answer 7

serotonergic systems

Question 8

Most focus has been on the ____ receptor

Answer 8

5HT-2

Question 9

Acid doesn’t cause permanent damage (T/F)

Answer 9

True

Question 10

What does acid unmask?

Answer 10

Psychiatric vulnerabilities/ depression/paranoid behavior

Question 11

What is the ED treatment of acid?

Answer 11

Chill out with em and support em for a minute, maybe give em benzos

Question 12

Magic mushrooms and mescaline have similar effects to what?

Answer 12

LSD

Question 13

PCP effects include which kind of appearance?

Answer 13

Unsettling, disturbed affect with rigid muscles

Question 14

What is wet in reference to PCP

Answer 14

A joint soaked in PCP

Question 15

What is the standard dose of PCP

Answer 15

5mg

Question 16

What is the onset time, plateau time, time of effect for PCP?

Answer 16

5, 45, and 4-6 hours

Question 17

How long can the PCP duration be?

Answer 17

24-48 hours

Question 18

The main effects of PCP are (3)

Answer 18

Euphoria, disconnected from world, flat affect

Question 19

A major clinical sign of PCP is

Answer 19

nystagmus

Question 20

To combat fatal PCP overdose , what should you use?

Answer 20

High potency first generation antipsychotic

Question 21

What are signs of a PCP overdose (4)

Answer 21

Muscle rigidity, Hostility, excess salivation without gag, increased BP

Question 22

What is the underlying mechanism of PCP

Answer 22

NMDA receptor antagonist, blocks Glu

Question 23

Is there permanent side effects of PCP

Answer 23

No, but chronic use results in dulled thinking/reflexes

Question 24

2 solutions for PCP overdose

Answer 24

Benzos and acidification of urine

Question 25

What is the dose of Molly?

Answer 25

75-300 mg

Question 26

Three clinical manifestations of molly?

Answer 26

Cognitive and perceptual disturbances, increased anxiety

Question 27

Why do people use pacifiers on molly?

Answer 27

To mitigate the effect of bruxism, or jaw clenching

Question 28

What two NTs does MDMA increase the vesicular release of?

Answer 28

Serotonin and dopamine

Question 29

Does MDMA cause fever?

Answer 29

probably not, likely an effect of the environment

Question 30

Chronic use of molly destroys _____ pathways

Answer 30

serotonergic

Question 31

Molly can cause ____ but rarely needs emergency treatment

Answer 31

dehydration

Question 32

What is a major effect of anticholinergics?

Answer 32

Waxing and waning of consciousness

Question 33

Anticholinergics can make patients ______, and they may need restraints because of their agitations

Answer 33

delirious; restraintants

Question 34

What is the major ocular sign of anticholinergic toxcicity

Answer 34

Fixed, dilated pupils

Question 35

Treatment of anticholinergic toxicity?

Answer 35

stop offending agent and restrain patient if needed

Question 36

Who loves to huff?

Answer 36

Ladies

Question 37

Ocular sign of huffing?

Answer 37

nystagmus

Question 38

What is another sign of huffing?

Answer 38

muscular incoordination

Question 39

What receptor is huffing mediated through

Answer 39

GABA-A

Question 40

What is a major CNS symptom of huffing?

Answer 40

Demyelination and cerebellar atrophy