Hamidullah Flashcards

1
Q

Which of the following microorganism cause Lymphogranuloma venereum?

A) Haemophilus ducreyi

B) Chlamydia trachomatis

C) Neisseria gonore

D) Treponema pallidum

E) Bartonella henselae

A

B) Chlamydia trachomatis

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2
Q

Which of the following virulence factor of fungus defining an aggregate of microorganisms to adhere each other on a surface?

A) Dimorphism

B) The motolerability

C) Biofilm

D) Capsule

E) Enzyme production

A

C) Biofilm

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3
Q

Which of the following form is the cause of relapse in plasmodial infections?

A) trophozoite

B) gametocyte

C) schizont

D) tachysporozoite

E) bradysporozoite

A

E) bradysporozoite

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4
Q

Which of the following is the infective form of the malarial parasites?

A) Ookinete

B) Gametocyte

C) Sporozoite

D) Oocyst

E) Schizont

A

C) Sporozoite

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5
Q

Which of the following antifungal binds to microtubules and inhibits mitosis of a certain fungi?

A) Amphotericin B

B) Azoles

C) Griseofulvin

D) Allylamines

E) Echinocandins

A

C) Griseofulvin

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6
Q

52.Which of the following dimorphic fungi infections frequently acquired while visiting bat caves without airway protection?

A) Sporothrix schenckii

B) Coccidioides immitis

C) Blastomyces dermatitidis

D) Paracoccidioides brasiliensis

E) Histoplasma capsulatum

A

E) Histoplasma capsulatum

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7
Q

Which of the following blood paranite causes most severe form of malaria?

A) Plasmodium falciparum

B) Plasmodium vivar

C) Plasmodium ovale

D) Plasmodium malarian

E) Plasmodium knowlesi

A

A) Plasmodium falciparum

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8
Q

Bacteria become resistant to which antimicrobial agent by the metabolic bypass?

A) Aminoglycoside

B) Macrolide

C)Trimethoprim

D) Tetracycline

E) Chloramphenicol

A

C)Trimethoprim

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9
Q

Which of the following antibacterial agent damage to the plasma membrane, leads to leakage of the cell contents and ultimately death of the cell?

A) Sulfonamides

B) Carbapenems

C) Macrolides

D) Polymyxins

E) Vancomycin

A

D) Polymyxins

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10
Q

Bacteria become resistant to which antmacrobial agent by replacing the last D-alanine with D-lactate in pentapeptide chain?

A) Trimethoprim

B) Vancomycin

C) Tetracycline

D) penicillin

E) Aminoglycoside

A

B) Vancomycin

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11
Q

Which of the following antibacterial agent inhibit the nucleic acid synthesis?

A) Chloramphenicol

B) Penicillin

C)Fluoroquinelones

D)Tetracyclines

E) Chindamycin

A

C)Fluoroquinelones

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12
Q

Which of the following method can be use to determine the antimicrobial susceptibility by a plastic strip that contain antibiotic gradient?

A) Agar Dilution

B) Disc Diffusion

C) Micro Dilution

D) E-test (Strip gradient test)

E) Broth Dilution

A

D) E-test (Strip gradient test)

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13
Q

Which of the following method can be used to determine the Minimum Inhibitory Concentration(MIC) of antibiotics on test tubes that include different antibiotic concentration?

A) Agar dilution

B) Broth dilution

C) Micro dilution

D) E-test (Strip gradient test)

E) Disc diffusion

A

B) Broth dilution

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14
Q

Which of the following antifungal binds to fungal membrane sterols and alters permeability?

A) Griseofulvin

B) Echinocandins

C) Amphotericin B

D) Allylamines

E) Azoles

A

C) Amphotericin B

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15
Q

Which of the following antibacterial agent inhibit protein synthesis by binding to 50S subunit?

A)Vancomycince

B) Macrolides

C) Fluoroquinolones

D) Aminoglycosides

E) Carbapenems

A

B) Macrolides

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16
Q

Which of the following is false for Coxialla burnetii?

A) Survive for months due to endospore formation.

B) Transmitted by arthropods

C) Cause zoonotic disease

D) Causative agent of Q fever

E) Does NOT cause skin rash

A

B) Transmitted by arthropods

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17
Q

Which of the following antimicrobial resistance mechanism is composed by efflux pump that expels the antibiotic before it reaches its target?

A) Enzymatic inhibition

B) Decreased uptake

C) Increased export

D) Altered target

E) Metabolic bypass

A

C) Increased export

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18
Q

Which of the following antibacterial agent inhibit synthesis of essential metabolites?

A) Macrolides

B) Aminoglycosides

C)Tetracyclines

D) Trimethoprim

E) Clindamycin

A

D) Trimethoprim

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19
Q

Which of the following method drug-impregnated absorbent paper use to determine antimicrobial susceptibility testing?

A) Agar Dilution

B) Broth Dilution

C) Micro Dilution

D) E-test

E) Disc Diffusion

A

E) Disc Diffusion

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20
Q

Which of the following fungus produce a large capsul that protect microorganisms from the host attacks?

A) Penicillium marneffei

B) Paracoccidioides brasiliensis

C) Aspergillus niger

D) Sporothrix schenckii

E) Cryptococcus neoformans

A

E) Cryptococcus neoformans

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21
Q

Which of the following releases from ruptured erythrocyte and produces bouts of shivering fever (paroxysms) and sweating in Malarial infections?

A) ring form

B) gametocyte

C) merozoite

D) sporozoite

E) bradysporozoite

A

C) merozoite

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22
Q

Which of the following mechanism bacterial resistance genes are carried from one bacteria to another by bacteriophages?

A) Pilus

B) Transposon

C) Conjugation

D) Transformation

E) Transduction

A

E) Transduction

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23
Q

Which of the following method a solid medium use to determine the Minimum Inhibitory Concentration of an antibiotic?

A) Agar Dilution

B) E-test

C) Micro Dilution

D) Broth Dilution

E) Disc Diffusion

A

A) Agar Dilution

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24
Q

Which of the following Plasmodium species cause Quartian malaria?

A) Plasmodium falciparum

B) Plasmodium vivax

C) Plasmodium ovale

D) Plasmodium malariae

E) Plasmodium knowlesi

A

D) Plasmodium malariae

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25
Which of the following define asexual life cycle of plasmodium? A) schizont B) sporogony C) sporozoite D) schizogony E) tachysporozoite
D) schizogony
26
Which of the following dimorphic fungi find block like arthroconidia in free-living stage? A) Paracoccidioides brasiliensis B) Sporothrix schenckii C) Blastomyces dermatitidis D) Histoplasma capsulatum E) Coccidioides immitis
E) Coccidioides immitis
27
Which of the following Chlamydia species also known as TWAR agent? A) C.trachomatis A, B, Ba, C B) C trachomatis L1, L2, L3 C) C.trachomatis (D-K) D) C.psittaci E) C.pneumoniae
E) C.pneumoniae
28
Which of the following dimorphic fungi cause rose-gardener's disease? A) Parococcidioides brasiliensis B) Penicillium marnefii C) Histoplasma capsulatum D) Sporothrix schenckii E) Blastomyces dermatitidis
D) Sporothrix schenckii
29
Which of the following fungus produce a large capsul that protect microorganisms from the host attacks? A) Penicillium marneffei B) Paracoccidioides brasiliensis C) Aspergillus niger D) Sporothrix schenckii E) Cryptococcus neoformans
E) Cryptococcus neoformans
30
The malaria parasite life cycle involves two hosts. Which of the following is the asexual life cycle of plasmodium? a) Trophozoites b) Merozoites c) Schizogony d) Sporogony e) Sporozoites
c) Schizogony
31
In which of the following method a plate with wells use for to determine the Minimum Inhibitory Concentrations (MIC) of antibiotics? a) Broth Dilution b) Disc Diffusion c) Micro Dilution d) Strip gradient test e) Agar Dilution
c) Micro Dilution
32
Which of the following survive for months due to endospore formation? a) Chlamydia psittaci b) Chlamydia pneumoniae c) Coxiella burnetii d) Rickettsia prowazekii e) Rickettsia rickettsli
c) Coxiella burnetii
33
Who as a garden hobby, which is may be the most risky fungal infection agent? a) Piedra hotea b) Malassezia furfur c) Criyptocccus neoformans d) Trichopyton rubrum e) Sporothrix schenckii
e) Sporothrix schenckii
34
Which of the following inhibit the cell wall synthesis? a) Polymyxin b) Chloramphenicol c) Clindamycin d) Macrolides e) Vancomycin
e) Vancomycin
35
Which of the following is not a dimorphic fungus? a) Malassezia furfur b) Penicillium marneffei c) Paracoccidioides brasiliensis d) Blastomyces dermatitidis e) Histoplasma capsulatum
a) Malassezia furfur
36
In which of the following mechanism bacterial resistance genes transfer by bacteriophages? a) Transformation b) Metabolic bypass c) Conjugation d) Transposon e) Transduction
e) Transduction
37
In which of the following bacterial resistance mechanism, membrane proteins expel the antibiotic from bacteria to the outside? a) Efflux Pumps b) Low affinity PBPS c) Metabolic bypass d) Transformation e) R plasmids
a) Efflux Pumps
38
Which of the following antimicrobial agent show its action on to the DNA of the bacteria? a) Cephalosporins b) Fluoroquinolones c) Macrolides d) Tetracyclines e) Carbapenems
b) Fluoroquinolones
39
Which of the following dimorphic fungal infection is commonly related to the inhalation of contaminated extracts of bats? a) Histoplasma capsulatum b) Penicillium marneffel c) Coccidioides immitis d) Blastomyces dermatitidis e) Sporothrix schenckii
a) Histoplasma capsulatum
40
The malaria parasite life cycle involves several stages. Which of the following is the infective form of the malarial parasites? a) Merozoites b) Sporozoites c) Trophozoites d) Schizont e) Gametocyte
b) Sporozoites
41
Which of the following is define accumulations of microorganisms aggregates on a surface? a) Dimorphism b) Capsule c) Cell wall components d) Enzyme production e) Biofilm
e) Biofilm
42
Which of the following method drug-impregnated absorbent paper use for antimicrobial susceptibility testing? a) Broth Dilution b) Disc Diffusion c) Micro Dilution d) Agar Dilution e) Macro Diffusion
b) Disc Diffusion
43
Which of the following antifungal drug inhibit the DNA synthesis of fungi? a) Griseofulvin b) Azoles c) Amphotericin B d) Flucytosine e) Echinocandins
d) Flucytosine
44
Which is not dimorphic fungi?
Candida albicans
45
Frie testi hangi hastalığın tanısında kullanılır?
C.trachomatis L1,L2,L3
46
Which drug inhibits synthesis of essential acids?
Sulfonamides
47
Where is end of sexual cycle of malaria forms?
The gut of mosquito
48
Transmitting resistance gene by pilus? A-)Conjugation B-)Transduction C-)Transformation
A-)Conjugation
49
True pathogenic fungal exhibit? A-) distribute around worldwide B-) very infective by respiratoy way C-)Thermal dimorphic D-)produce spore E-)produce mycelium
C-)Thermal dimorphic
50
Which drug could inhibit by beta lactamase enzyme? A-)Vancomycin B-)Cephalosporin
B-)Cephalosporin
51
Kapsül oluşturan?
C.neoformans
52
Which drug types inhibit synthesis of ergosteral enzyme?
Azoles
53
Which infective form of Malaria enter human body?
Sporozoite
54
Which of the following antibacterial agent shows its effect on metabolism of folic acid? A) Vancomycin B) Aminoglycosides C) Fluoroquinolones D) Beta Lactam Drugs E) Sulphonamides
E) Sulphonamides
55
Some species of Plasmodium are human-host specific Plasmodium species. Which of the following Plasmodium species can cause malaria in both human subjects and animals? A) P. falciparum B) P. ovale C) P. knowlesi D) All the above E) None of the above
C) P. knowlesi
56
Which of the following dimorphic fungi causes Lymphocutaneous infection when contaminated plant matter penetrates the skin? A) Histoplasma capsulatum B) Coccidioides immitis C) Blastomyces dermelitials D) Paracoccidioides brasiliensis E) Sporothrix schencidi
E) Sporothrix schencidi
57
Which of the following term is describing plasmids transferred via sex pili? A) Bacteriophage B) Transposon C) Conjugation D) Transformation E) Transduction
C) Conjugation
58
Which of the Plasmodium species gametocytes is "banana shaped"? A) Plasmodium falciparum B) Plasmodium vivax C) Plasmodium ovala D) Plasmodium malariae E) Plasmodium krowlesi
A) Plasmodium falciparum
59
Which of the following microorganism fever? A) Rickettsia prowazekii B) Rickettsia typhi C) Bartonella henselae D) Ehrlichia sennetsu E) Coxiella burnetii
E) Coxiella burnetii
60
Which of the following dimorphic causes "Rose gardener's disease"? A) Histoplasma capsulatum B) Coccidioides immitis C) Blastomyces dermatitidis D) Paracoccidioides brasiliensis E) Sporothrix schenckii
E) Sporothrix schenckii
61
Which of the following antibacterial agent inhibit the nucleic acid synthesis? A) Chloramphenicol B) Penicillins C) Fluoroquinolones D) Tetracyclines E) Clindamycin
C) Fluoroquinolones
62
Which of the following is the infective form of the plasmodial parasites? A) Ookinete B) Gametocyte C) Sporozoite D) Oocyst E) Schizont
C) Sporozoite
63
Which of the following does not inhibit the protein synthesis? A) Aminoglycosides B) Macrolides C)Clindamycin D) Fluoroquinolones E) Tetracyclines
D) Fluoroquinolones
64
Which of the following microorganism cause Recrudescent typhus (Brill-Zinsser disease)? A) Coxiella bumetii B) Rickettsia tsutsugamushi C) Rickettsia typhi D) Bartonella henselae E) Rickettsia prowazekii
E) Rickettsia prowazekii
65
Which of the following dimorphic fungi infections frequently acquired while visiting bat caves without airway protection? A) Sporothrix schenckii B) Coccidioides immitis C) Blastomyces dermatitidis D) Paracoccidioides brasiliensis E) Histoplasma capsulatum
E) Histoplasma capsulatum
66
Which of the following microorganism is causative agent of Q fever? A) Rickettsia prowazekii B) Rickettsia typhi C) Ehrlichia sennetsu D) Coxiella burnetii E) Bartonella henselae
D) Coxiella burnetii
67
Which of the following is not a dimorphic fungus? a) Blastomyces dermatitidis b) Penicillium marneffei c) Aspergillus niger d) Paracoccidioides brasiliensis e) Histoplasma capsulatum
c) Aspergillus niger
68
Protein Synthesis inhibition
Oxazolidinone
69
Polyenes gurubundan olanı?
Amphotericin B
70
inhibit the ergesterol synthesis
- Allylamines
71
inhibit the ergesterol synthesis
Allylamines
72
which is the earlier stage of the malaria?
ring form
73
B lactamase enzimi hangi sistemi kullanir?
enzyme inhibition
74
macrospore ve microspore'un birleşip zigot oluşturduğu yer?
-stomach of mosquito
75
Q Fever ile ilgili hangisi yanlıştır? A-Hava yoluyla bulaşan bir hastalıktır B-Causative agent sensitive to environmental condition C- Causitive agent can not cause casisitive D- Causetive agent is coxiella burnetti E-Causetive agent is zoophilic.
B-Causative agent sensitive to environmental condition
76
30s'e bağlanarak protein sentezini inhibe eden antimicrobial agent? A-Sulfanomide B-Tetracyclines C-Macrolides D-Carbapenem E-....
B-Tetracyclines
77
kümes hayvanlarından bulaşan ve atypic pneumonia etkeni nedir? chlamydia psittaci
chlamydia psittaci
78
exoerythrocytic stage nerede olur?
Liver tissue of human body
79
Which of the following plasmodium species can be distinguished from the others by the gametocyte form on a thin smear? a) Plasmodium falciparum b) Plasmodium malariae c) Plasmodium vivax d) Plasmodium ovale e) Plasmodium knowlesi
a) Plasmodium falciparum