Hard drugs 💊

Question 1

Somatostatin analogue

Answer 1

Octreotide

Question 2

Tamoxifen mode of action (cancer treatment)

Answer 2

selective oestrogen receptor modulator

Question 3

Cellulitis treatment

Answer 3

flucloxacillin

Question 4

Drug that inhibits prostaglandin production

Answer 4

Asprin

Question 5

Staph aureus treatment

Answer 5

Flucloxacillin

Question 6

Atropine mode of action

Answer 6

antimuscarinic

Question 7

What type of receptors does adrenaline act on

Answer 7

G protein-coupled receptors

Question 8

May cause gout

Answer 8

Thiazides

Question 9

Furosemide drug class

Answer 9

Loop diuretic (inhibits the Na-K-Cl cotransporter)

Question 10

May affect growth if used in young children

Answer 10

Inhaled corticosteroids

Question 11

Inhibits the Na-K-Cl cotransporter in the thick ascending limb of the loop of Helne

Answer 11

Furosemide

Question 12

Used in management of stable adult asthma for those not controlled with a SABA + ICS

Answer 12

Leukotriene receptor antagonists

Question 13

Inhibit peptidoglycan cross linking

Answer 13

Cephalosporins

Question 14

Adenosine and beta blocker contraindication

Answer 14

Asthma

Question 15

Drug contraindication to concurrent verapamil therapy

Answer 15

Beta blockers

Question 16

Amiodarone side effect

Answer 16

Bradycardia

Question 17

Amlodipine side effect

Answer 17

Headache

Question 18

Impotence is a side effect of

Answer 18

Beta blockers

Question 19

Destroys amoxycillin

Answer 19

Beta lactamase

Question 20

Treatment for anaerobic infections

Answer 20

Metronidazole

Question 21

Inhibit protein synthesis by acting on the 30S subunit of ribosomes

Answer 21

Aminoglycosides and tetracyclines

Question 22

Treatment for infective exacerbation of COPD

Answer 22

iSOAP: ipratropium, salbutamol, oxygen, amoxicillin, prednisolone

Question 23

Diuretic for ascites

Answer 23

Spironolactone

Question 24

All patients post MI should be started on

Answer 24

ACE-inhibitor, beta-blocker, high intensity statin, anti-platelet therapy

Question 25

Reduce variceal bleeding

Answer 25

Beta-blockers (propanolol)

Question 26

drug ending in -dipine e.g. amlodipine

Answer 26

Calcium channel blocker

Question 27

drug ending in -olol e.g. propranolol

Answer 27

beta-blocker

Question 28

drug ending in -pril e.g.ramipril

Answer 28

ACE inhibitor

Question 29

drug ending in -sartan e.g. losartan

Answer 29

ARB

Question 30

Steps of hypertension management

Answer 30

1. A or B, unless >55 or black -> C 2. A + C, if black ARB instead of A. D if C not tolerated 3. A + C + D 4. A + C + D + D (extra thiazide/ spironolactone)

Question 31

Treatment for peptic ulcers

Answer 31

Antacids, H2 antagonists, PPI

Question 32

Uc/crohn's treatment steps

Answer 32

5-ASA Steroids Immunosuppression Anti-TNF drugs

Question 33

Anti-diarrhoeal

Answer 33

Loperamide

Question 34

Drug class that blocks the enzyme that inserts the viral genome into the DNA of the host cell

Answer 34

Integrase inhibitors ("gravirs")

Question 35

Important cause of agranulocytosis

Answer 35

Clozapine

Question 36

Targets protein synthesis in bacteria

Answer 36

Erythromycin

Question 37

Inhibit sodium reabsorption by blocking the Na+Cl- symporter at the beginning of the distal convoluted tubule

Answer 37

Thiazides

Question 38

Blocks NMDA receptors

Answer 38

Ketamine

Question 39

Anti-platelet, decreases formation of thromboxane A2 resulting in decreased platelet aggregation

Answer 39

Aspirin

Question 40

Metronidazole mode of action

Answer 40

Damages DNA

Question 41

Gentamicin drug class

Answer 41

Animoglycoside

Question 42

How does adrenaline treat anaphylaxis

Answer 42

by acting on alpha-adrenergic receptors and causing vasoconstriction

Question 43

____ are a cause of impaired glucose tolerance

Answer 43

Thiazides

Question 44

Monoclonal antibody drugs typically end in

Answer 44

'-mab' | stands for Monoclonal AntiBody.

Question 45

Troponin I binds to ___ to hold the troponin-tropomyosin complex in place

Answer 45

actin

Question 46

Why is heparin classed as a low volume drug

Answer 46

It has a low volume of distribution