Head and Neck Flashcards

(77 cards)

1
Q

DDx Cervical Lymph Node?

A

Infection, Lymphoma, Mets

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2
Q

HPI for Cervical Lymph Node?

A

URI, sore throat, TB exposure
HIV, B symptoms
h/o cancer, XRT, thyroid sx, previous surgeries

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3
Q

Imaging for Cervical Lymph Node?

A

CXR infectious or malignant if positive get CT neck and chest
US guided FNA
PET if recurrent dz or met activity

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4
Q

What is Tx based on for a Cervical Lymph Node?

A

Benign (clear h/o sore throat or URI)-
observe for several weeks possible ABX and if persist w/u and remove
Lymphoma (can be dx based on FNA but still needs excision for final path confirmation),
stage it! CT N/C/A/P + BM bx (stage 4)-> CHOP
SCC- (See below for more exhaustive detail)
(2 Tests before any surgery!) CXR and Panendoscopy, CT H&N, if found excise primary site and MRND and 5000 rads
if still negative put patient to sleep -> direct laryngoscope c random bx of suspicious tissue (nasopharynx, base of tongue)
nothing - assume is mets and perform a radical neck dissection and give 5000 rads to entire neck
adenocarcinoma from (Broad-thyroid, lung, breast, salivary glands, prostate, GI) -
EXTENSIVE w/u all and if none is found including ER/PR and Mucin -> MRND, give 5000 rads (entire neck?) XRT and follow
if primary is found = Stage 4 dz and chemo may be offered

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5
Q

Describe a MRND?

A

create skin subplatsymal skin flaps
locate and protect mandibular (parallel to lower border of mandible) and cervical branches when creating superior flap
commence in posterior triangle anterior to trap removing areolar and lymphatic tissue
divide external jugular vein ) posterorinferior corner of dissection)
attempt to save the spinal accessory nerve unless involved with tumor
continue along anteriorly superiorly to the clavicle
ID phrenic nerve on anterior scalene b/w brachial (laterally) and IJV (medially and inside the carotid sheath ligate close to clavicle and avoid thoracic duct left side) , severing the omohyoid muscle to to provide better exposure and dividing SCM
divide anterior facial vessels as dissection heads superiorly
ID hypoglossal crosses 1 cm above the carotid bifurification
also ID lingual nerve and salivary duct to facillitate removal of submental and submandibular triange
remove contents of sub mental and submandibular triangles
Ligate submax duct
leave drains

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6
Q

Neck Mass DDX?

A

LN, primary neck tumor, congenital mass, sarcoidosis

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7
Q

Neck Mass HPI?

A

Hx- Very Important ! age of patient, duration, location, palpation
age
Hx- smoker, previous cancers, surgeries, URI, B symptoms, XRT

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8
Q

Neck mass Significance of age, location and timing

A

age
young patients- congenital, lymphadenitis, leukemias and lymphoma
middle aged- lymphoma, primary neck tumors
Elderly-Neoplastic
Location
over LN- enlarged LN,
Carotid bifurication- carotid body tumor
over anterior border of SCM- branchial cyst;
midline above thyroid- Thyroglossal cyst
midline, submental and firm- dermoid cyst
Posterior triangle, cystic- cystic hygroma
duration
few weeks- infectious vs few months to years - congenital or neoplastic

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9
Q

Neck mass PE?

A

PE- complete H&N, ENT, skin lesions, scars, LNs, liver & spleen, B sx,
how it feels, color

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10
Q

Neck mass test? and Labs?

A

U/S - cystic? solid?
FNA if vascular –> MRI
still no then pan-endoscopy (bronch, upper endoscopy, colonoscopy)
CXR, abdominal CT, PET
labs- CBC, +-TFT, calcitonin, calcium
if lymphoma needs core or excisional biopsy
Older age and + risk factors- CT H&N

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11
Q

Treatment of congenital neck tumors?

A

Congenital- usually young
Carotid body tumors, ganglionomas, schwanommas, cystic hygroma (posterior triangle, young), teratoma, branchial cyst = Tx local excise
Hemangioma -Observe; capillary or cavernous, AVMs—>embolize then excise
Branchial Cleft Cyst
1st cleft- open at angle of mandible, passes through facial nerve
2nd cleft- open anterior of the SCM passes b/w carotid bifurication
3rd cleft- open at lower border of SCM, passes behind carotid
Thyroglossal cyst (if infected, growing or concerned)—>sistrunk procedure
(transverse incision over mass, dissect off strap muscles, follow sinus tract down to base of tongue, include middle hyoid bone c specimen)

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12
Q

Treatment of cancer and sarcoidosis of the neck?

A

Cancer (mostly elderly patients)
Adenocarcinoma, SCC, BCC, sarcoma, melanoma (Needs SLNB), Testicular = resection of primary (if known) +- MRND, XRT
Lymphoma = staging CT scan, BM bx= stage I,II ->XRT; stage III,IV —>CHOP
Sarcoidosis
young black female c joint pain, CXR (b/l patchy), path - noncaseating granuloma, Tx- Steroids

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13
Q

RF for SCC of the Oropharynx

A

RF- ETOH, Smoking, other lesions removed

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14
Q

PE for SCC of the Oropharynx

A

Bimanual palpation, visual inspect, indirect laryngoscopy, LN

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15
Q

Staging and treatment for those stages of SCC of the Oropharynx

A

Stage 1 = 5 mm margins
Stage 2 = 2-4cm —>1 cm margins
Stage 3 = >4cm or node positive wide margins >1cm , MRND, 5000 rads
Stage 4 = distant mets- neoadj chemo and radiation
For stage 1 or 2 single modality surgery or radiation depending on how accessible it is (ex vocal cords) anterior vs posterior
If lesion not accessible (oral posterior, tonsils) then 6000 Rads and rebiopsy for residual tumor
Stage 3 or 4 combined modality (if involved LN to neck should get XRT to ENTIRE neck)

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16
Q

Treatment for SCC of the Oropharynx

A

For stage 1 or 2 single modality surgery or radiation depending on how accessible it is (ex vocal cords) anterior vs posterior
If lesion not accessible (oral posterior, tonsils) then 6000 Rads and rebiopsy for residual tumor
Stage 3 or 4 combined modality (if involved LN to neck should get XRT to ENTIRE neck)
consider doing just agree full thickness skin graft behind ear or base of neck
wedge resection of lip c 0.75 - 1 cm margins if total less 1/3 of length of lip if larger than advancement flap
XRT
medial canthus of eye or nose
5000 rads if close margins

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17
Q

Salivary Gland PE and HX?

A

mass at angle of mandible in front of ear
not tender or is it painful?, no smoking
PE if roll mass over the mandible if it sinks under likely a LN
assess facial nerve function! (runs right in b/w the parotid)

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18
Q

Salivary Gland testing?

A

FNA differentiate epithelial vs non epithelial

epithelial (Mixed, Warthin, Adenoma) vs non epithelial (cyst, LN, Hemangioma, Lipoma) —>get a high res US

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19
Q

Salivary gland imaging?

A

CT scan- det depth, size, invasion, LN enlarged

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20
Q

Salivary gland surgery?

A

Superficial parotidectomy c FS (low or high grade?)
malignant low grade- total parotid +- post op XRT
malignant high grade- radical parotid +MRND +postop xrt

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21
Q

Salivary gland consent?

A

Superficial Parotidectomy

preop consent- facial nerve injury, Freys syndrome, salivary fistula

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22
Q

Borders of a parotid gland resection?

A

Anatomic borders of parotid:
ant- mandibular rami
post- tympanic portion of temporal bone and mastoid process,
sup by external acoustic meatus, zygomatic arch, TMJ.

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23
Q

Describe a parotidectomy for salivary gland tumor?

A
  1. Don’t use paralytics, and have nerve stimulator
  2. Preauricular incision following angle of mandible (Mod Blair)
  3. Raise subplatysmal flaps
  4. Identify and save main trunk of greater auricular nerve divide branches that go into parotid
  5. Divide posterior facial vein but save retromandibular vein (prevents venous engorgement)
  6. As dissection cont anteriorly peripheral branches of facial nerve appear. Dissect superficial to them and spare them!
  7. Mobilize anterior border of SCM develop plane b/w muscle and mastoid
    divide the temporoparotid fascia
  8. Expose main trunk of facial nerve inferior to membranous portion of external auditory canal. (styloid process is deep and post belly of digastric is superficial)
  9. Trace trunk of facial nerve into parotid and dissect branches distally.
  10. Remove superficial lobe of parotid by dissecting in plane of nerve. (Nerve is b/w superficial and deep lobe)
    Send frozen and if benign you are done
    II. Close over drain.
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24
Q

Malignant Salivary gland parotid treatment?
Tumor adherant to nerve?
Massive tumors involving facial nerve with paralysis pre op?
suspicious nodes or high grade lesion?

A

Malignant-Complete conservative parotidectomy (spare facial nerve and branches)
-Tumor adherent to nerve- dissect off nerve and radiation 5000-6000 gy
-Low grade tumor involving portion of facial nerve treat with subtotal parotidectomy with preservation of uninvolved branches
-Massive tumors involving facial nerve with paralysis pre op can sacrifice nerve.
If nerve worked preop then attempt nerve graft -
MRND if suspicious nodes or high grade lesion they tends to metastasize.

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25
ID facial nerve in Salivary gland tumor?
ID facial nerve - ext auditory canal cartilage (Superficial) - nerve is 1 cm deep and inf to the tip posterior belly of digastrics m (Superficial )- nerve is deep to it Styloid process (d eep)- nerve is superficial to it
26
facial n branches and treatment for severed?
facial n branches- The Zebra Bit My Cat - temporofrontal (eye brow lift procedure), Zygomatic (lateral torsoraphy to close eye), Buccal (nothing, min dysfunction), Mandibular (need to sever contralateral if injured) Cervical (platsyma) facial injured- c/s PRS immediate repair, microscope, collagen tube c silicone glue 10 prolene
27
Frey Syndrome?
Freys Sx- rarely needs tx, botox, raise flap of skin and put facia or allured under the flap
28
Thyroid Nodule (palpable) ddx?
DDx- cyst, adenoma, hyperplastic nodules, thyroiditis, cancer papillary, follicular, medullary, Hurthe, anaplastic
29
Thyroid Nodule (palpable) PE
PE-Have pt swallow, does it move up and down c thyroid cartilage (thyroglossal duct cyst moves up and down c swallowing as well as tongue protrusion), compressive sx, mobility, size, LNs, hard, fixed, Phebertons sign (facial plethora, neck vein distension, dyspnea thoracic inlet obstruction) >1 cm nodule is significant
30
Thyroid Nodule (palpable) HPI?
Hx- h/o XRT, FHx, Thyroid hx, onset of sx, dysphagia, dysphonia, hoarseness, MTC (diarrhea/flushing), hyper/hypothyroid sx, Thyroiditis (Cold, cough,URI) rapid growth and new onset hoarseness- concerning
31
Thyroid Nodule (palpable) work up?
Blood test TSH and if abnormal get thyroid fxn test, T4 Thyroid Antibodies anti-peroxidase, anti-thyroglobulin (r/o thyroiditis) thyroglobulin (imp for f/u) calcitonin/calcium (if suspect Medullary cancer (from hx) or parathyroid (elevated calcium) If low TSH --> diff Graves vs toxic nodule via thyroid scintigraphy which will be High uptake in Graves U/S is IOC for a newly dx nodule (size, location, LN) susp for malignancy (hypoechoic, irregular, extracapsular) TSH elevated or normal - U/S FNA (FNB is tech a delicate procedure try not to mention it) avoid FNA in Graves can cause thyroid storm
32
FNA results of Thyroid nodule and next step?
FNA Fluid- clear - observe; clear but doesn’t disappear- FNA again or hemithyroidectomy; Bloody- send off and do hemithy Solid Benign 70% - F/U US 6mo Goiter - see below Non dx or Atypia or follicular lesion of undetermined significance - Repeat FNA Follicular Neoplasm 15% -Lobectomy c only permanents because frozens unreliable Suspicious malignancy - Lobectomy with frozens or total thyroid Malignant - Total thyroidectomy Medullary (amyloid on FNA)- total thyroidectomy and elective central LND +ipsilateral MRND
33
Treatment for follicular, anaplastic, papillary, graves, toxic and non toxic solitary nodule, multinodular?
Follicular cancer /Hurthle Cell (more aggressive and doesn’t respond to I131)on final path —> total thyroidectomy (don't do frozen) Papillary frozens are OK for pap —> Total thyroid (easier to monitor and treat with a total postoperatively i.e. postop I131 and scanning) central node dissection is better than cherry picking if palpable nodes Graves -Tx Total>RAI>PTU Toxic Solitary Nodule -Tx Lobectomy>RAI Non-Toxic Nodular Goiter- Tx thyroxin suppression for six months if nodule persist or enlarges —> hemithyroidectomy Toxic Multinodular goiter - Tx Subtotal >RAI Anaplastic - Tx Adriamycin , XRT 3wks, debulking surgery-almost always lethal usually not resectable and mets- D/W pt tracheostomy
34
preop of graves?
2 weeks of PTU, Lugols for 10 days, Propanolol to ctrl HR
35
Describe Thyroidectomy and subtotal
Thyroidectomy- extend neck, consider nerve stimulator transverse cervical incision raise flaps incise median raphe and mobilze strap muscles ID medial vein ligate and divide look out for (RLN posterior) ID and mobilze superior pole ligate and divide vessels (External SLN Cricothyroid mm) ID and ligate inferior pole vessels medial —>lateral (watch out for RLN) near Ligament of Berry close to inferior pole (right loops around the Subclavian artery) ID and protect Parathyroids Divide Berrys ligament mobilizing the thyroid from trachea mobilize isthmus and pyramidal lobe Contralateral side close strap muscles, and platysma don’t leave drain (unlike parotid) Subtotal - leave some thyroid and the inferior and superior poles to help avoid nerve on occasion I have left tissue on top of the trachea by going through the substance of the gland with a small hemostat curved side up down avoid injury the RLN
36
Complications of thyroid surgery and treatment
inadvertant parathyroid injury transfer to SCM Nerve intrapped in tumor the nerve should be sacrificed Hyperthyroid crisis fever, tachy , respiratory arrest and coma, tx NS bolus, versed, Lugols, PTU Hydrocortisol, propanolol, O2, Tylenol inadvertant RLN injury during thyroid surgery should stop the resection of the other half (assume midline position and retract later)
37
Post op thyroidectomy? And followup?
24hrs postop admission to monitor for HTA, Hypocalcemia minimized with oral calcium supplements and d/c after 1 week F/U Tx- start T3 Synthroid 0.125 mg , follow TG and TSH levels, after surgery stop T3 so TSH can rebound and perform I121 scan to detect residual tumor and if there is —> I131 ablation repeat scans and if still there then reexplore and excise and ablate
38
Non-Toxic Benign Goiter causes?
defective thyroxin synthesis which the pituitary then secretes more TSH, so increase in gland size but euthyroid some develop hypothyroidism
39
Non-Toxic Benign Goiter work up?
thyroid profile, US to r/o nodule, FNA can give path confirmation of benign goiter and r/o cancer in nodule (rare) Need TRH stim test (rarely done anymore) to see how they respond and if they do —> synthroid TFTs repeat bx in 6 mos and repeat evaluation- if toxic on labs then PTU
40
Non-Toxic Benign Goiter treatment?
Most patients get I131 usually 50% reduction by 12-18 mo (RAI only works on functioning tissue and most non toxic goiters are nonfunctioning so really doesn’t work) Surgery reserved for compressive sx, suspect malignancy, thyrotoxicosis, cosmesis, TRH unresponsive, failed thyroxin for 1 yr Subtotal thyroidectomy no special prep for euthyroid
41
Hyperthyroidism ddx
Causes- Diffuse goiter (Graves), nodular goiter, adenoma, thyroiditis
42
Hyperthyroidism HPI and PE
Dx- made by symptoms ( palpitation, heat loss, weight loss, good appetite , fine tremors) PE- hyperreflexia, tachy, a fib, sweating, thyroid enlarged
43
Hyperthyroidism w/u
Thyroid profile-Free T4, TSH, TSI, anti TPO, anti TG high resolution US No FNA can cause hyperthyroidism crisis unless nodule I123
44
Hyperthyroidism treatment
Radioactive I131 MC 1-2 doses, slow treatment, high chance of hypothyroidism, no pregnancy for 1 yr, good for elderly Surgery- total thyroidectomy indications - children or women who are or will be pregnant compressive symptoms presence of thyroid nodule (unable to r/o cancer) failure of meds tx after 1-2yrs cosmesis Meds PTU and Tapazole Surgery prep for Graves PTU until day of surgery lugols solution (iodine) 2 cc TID for 10d preop Inderal for tachycardia
45
Hyperthyroidism crisis Sx and Tx?
(hyper metabolic state can quickly develop into respiratory arrest , coma (fever, and cardiac arrythmias) IV fluid, Sedation, Lugols (blocks thyroxin), PTU, Hydrocortisone, Inderal, Antipyretics, O2
46
F.U treatment for graves?
F/U thyroxin for life by TSH levels
47
Papillary Thyroid Carcinoma surgery with questionable parathyroid
autograft any PT gland that have questionable viability; PT gland must be reduced to pieces that can survive on the diffusion of nutrients temporarily while neovascular growth occurs in weeks
48
Papillary Thyroid Carcinoma prognosis
GAMES- gender, age, mitosis, extra capsular invasion, size Age is the most important Worst for males
49
Papillary Thyroid Carcinoma w/u
US FNA - solid, hypo echoic nodule larger than 10 mm Nuclear thyroid scintiscan only if TSH suppressed Preoperative US to evaluate central and lateral cervical LN is required lateral neck node c TG of the aspirate can determine the presence of mets papillary thyroid carcinoma then need neck dissection 2,3,4,6
50
Papillary Thyroid Carcinoma complications
RLN paresis usually resolves days to months; if unilateral if permanent then palliation of the cord immobility and voice changes cane be achieved by vocal cord injection or larynoplasty mild hypocalcemia c tingling, oral calcium 500-1500mg PO BID-QiD more extreme - IV calcium gluconate
51
Additional treatment for papillary thyroid carcinoma
Papillary thyroid cancer can concentrate iodine can deliver RAI over several weeks best when TSH is elevated (remove gland or administer recombinant TSH)
52
Medullary Thyroid Cancer HPI and PE
Flushing, diarrhea, FHx, (Stones, Moans, Groans etc to r/o PT problems)
53
Medullary Thyroid Cancer w/u?
U/S and FNB will demonstrate MTC Calcitonin, CEA, Calcium, RET gene testing not MEN other labs - urine and plasma metanephrines to r/o Pheo, PTH to r/o PT r/o Pheo MEN2A (Parathyroid Hyperplasia, Pheo, MTC) mets w/u Check a CT scan A/P once cancer is established 2/2 to mets
54
Medullary thyroid cancer with RET surgery?
1st resect —>Pheochromocytoma 2nd —> thyroidectomy
55
Surgery for Medullary thyroid cancer in description
total thyroid and Px central neck (level 6) and if LN mets --> lateral neck dissection 2,3,4,6 hockey stick incision transverse incision below cricoid total thyroidectomy central neck dissection ID RLN and remove fibroadipose tissue b/w two carotid sheaths from hyoid sup and Brachiocephalic vessels inferiorly LN tissue anterior and posterior triangles defined by submandibular gland superiorly the IJ vein medially , traps laterally and clavicle inferiorly is removed avoid injury to brachial plexus or phrenic nerve medial aspect of SCM is reapprx to sternothryroid muscle, followed by platysma
56
Describe a MRND? Borders?
MRND borders - sup- digastrics, Post- CN 11, Inferiorly- thoracic inlet inferiorly hockey stick incision- transverse cervical c vertical extension along border of trapezius on neck (avoid carotid vessels) raise subplastymal flaps ID protect marginal mandibular nerve located inferior margin of mandible (danger during superior flap) be careful inferiorly of phrenic nerve on left be careful of thoracic duct mobilize SCM laterally and strap muscles medially dissect level 6 nodes off jugular vein and dissect level nodes 5 b/w SCM and trapezius dissect level 2/3 superiorly to the mandible take level 6 nodes
57
Complications of MRND? and treatment?
Complication ID injury to thoracic duct intraop - ligate with prolene ID thoracic duct injury postop- milky white high TG place pt on fat free diet, abx, pressure dressing if not resolved then OR for ligation HTA , tracheal compression open immediately at bedside followed by reoperation to evaluate cause of bleeding
58
F/U for Medulary thyroid cancer
F/U calcitonin and CEA 6mo then yearly after 2 x Place on synthrod Px RET gene total thyroidectomy and central LND childhood
59
Hyperparathyroidism DDx
DDx- malignancy, primary hyperparathyroidism (Adenoma (usually single) >>hyperplasia, Ca), secondary (renal failure), Benign Familial hypocalciuric hypercalcemia, thiazide
60
Hyperparathyroidism PE
present with a lab value increase in ca or depression and fatigue, 5th- 6th decade hx- stones, bones, moans, psych overtones PE-chovsteck signs, trousseaus (carpal spasms)
61
Hyperparathyroidism w/u
always repeat the calcium level no matter what they give you Calcium, PTH, 24 hr urine ca to r/o BFHH (its usually low), Alk Phosp (high will indicate good possibility for bone hunger post op) iPTH, creatine, vit D determine if non parathyroid mediated Localize- U/S and Sestembi scan of neck and mediastinum reop- selective angiography DEXA scn
62
Function of PTH?
PTH - increases osteoclastic, stimulates renal calcium absorption
63
Indications for surgery of hyperparathyroidism?
``` indications for tx Cancer Sx calcium >11.5 decreased creatine clearance T score ```
64
Surgery for hyperparathyroidism description?
Surgery First send baseline PTH and calcium level supine neck externsion 4-5 cm transverse cervical incision subplatsymal flaps to thyroid cart, SCM, substernal notch divide straps along median raphe and dissect off lateral thyroid lobes start with the lobe that was localized o/w start c right lower PT (MC for adenoma) ID RLN and ITA mobilize thyroid lobe medially ID PT gland usually in thyrothymic tract anterior to the RLN and inferior to thyroid lobe next ID Superior PT gland usually 1 cm of the RLN as it enters cricoidthyroid membrane and posterior to the thyroid lobe ID all 4 glands especially if doing 3 1/2 gland excision prior to excision of abnormal gland (if questionable PT tissue can do bx or aspirate send IO PTH to confirm PT tissue and excise abnormal gland after adenoma excision send IO PTH if drops by 50% w/in 15 minutes or back to normal close. Half life is 3.5 min PTH
65
Multigland hyperplasia hyperparathyroidism treatment?
leave a normal sized remnant (usually for sporadic), or total with implantation to brachioradialis muscle in forearm (MEN) if removing 3 1/2 glands, always start out with removing half of the first gland you ID and observe it . if it becomes ischemic, repeat the procedure with the second gland, and so on. have to preserve blood supply
66
Parathyroid cancer treatment?
found incidentally intrapoeratively en bloc resection with ipsilateral thyroid lobe and central compartment LN is appropriate
67
Parathyroid cancer with mets treatment?
palliative resection and bisphosphonates and calcimimetics, chemo and XRT rarely effective Calcitonin acts quicker where bosphosphinates ca take a while
68
Missing parathyroid? Still cant find it?
Missing parathyroid retropharyngeal space carotid sheath open from the level of the carotid bifurcation to base of neck inferiorly- check thymus gland should be exposed (thymectomy) intrathyroid PT tumor should be considered all four glands found but still high PTH suspect a 5th PT gland still can’t find use intraoperative imaging neck US c FNA don’t enter mediastinum during this first go
69
if Alk phosp was high preop suspect bone hunger post operatively prior to a parathyroidectomy?
calcium supplementation and calcitriol usually restored in 24 hrs
70
When to use cryopreservation of parathyroid gland?
Cryopreservation- borderline cases where you only find 3 glands normal gland and you missed or patient only has 3 glands allows you to reimplant if you find in your studies no residual parathyroid tissue
71
Initial steps when given a case that is Persistent Hyperparathyroidism from another surgeon?
Consider a tertiary center review imaging, path, operative reports where was the RLN? labs op report- exploration carotid sheath? thymectomy? exploration TE groove? exploration of other side of neck? reexamine indications for surgery reop there is risks injury to RLN, perm hypothyroidism r/o other causes of hypercalcemia, meds, 24 hr urine to r/o BFHH
72
W/U to perform when given a persistent hyperparathyroidism case?
Two test U/S - evaluates superficial structures perithyroid, intrathyroid tissue, thyroid nodules, carotid sheath down to mediastinum, c FNA (doesn’t evaluate deeper structures) Sestamibi tech 99- evaluates deep structures mediastinum, posterior to larynx, trachea, esophagus) consider CTA localize missing adenomas (adenomas will light up on arterial phase) Selective venous scan - invasive
73
What to do during the operation prior with persistent hyperparathyroidism?
Preop- laryngoscopy to document vocal cord dysfunction from unrecognized RLN injury IO RLN monitoring baseline PTH and calcium suspected PT send for frozens r/o misidentification IO PTH monitoring failure for PTH to drop >50% after 10 minutes should prompt further exploration
74
MC location missing parathyroid adenoma? Inferior and superior areas?
regular anatomical position inferior PT glands typically 2 cm area around inferior pole Superior PT glands typically 2cm superior to to RLN as crosses ITA MC ectopic area INFERIOR is cervical thymus, ipsilateral thyroid lobe, carotid sheath, anterior mediastinum (inappropriate to search unless seen on preop imaging ) MC ectopic area SUPERIOR - path of superior pedicle deep along preverterbral fascia, TE groove (should mobilize trachea and esophagus to view retrolaryngeal and retropharyngeal gland)
75
What to do with Multiglandular dz hyperparathyroid?
complete cervical exploration and excision of PT tissue and reimplant appx 30-40mg morsalized PT tissue into non dominant brachioradialis musce cryopreservation- residual PT tissue should performed so when detectable hypoparathyroid is high then can reimplant PT tissue (which was histo proven)
76
How do you get and how to treat Parathyromatosis?
Parathyromatosis (abnormal PT tissue surrounding contiguous structures 2/2 to previous surgery diffuse seeding) complete excision of all identifiable PT implants including resection of involved strap m, thyroid lobe as well as ipsilateral central LN dissection
77
Post op management and follow up of parathyroidectomy surgery?
F/U - 1-2 wks eval for hypocalcemia, vocal strenth check calcium and PTH 6 months and yearly if low then reimplant cryo preserve or activated 1,25 OH Vitamin D