Head and Neck Cancer Flashcards

(40 cards)

1
Q

Risk factors/cause

A

Tobacco smoking (important factor: frequency and length of consumption)
Alcohol consumption
Combination of tobacco and alcohol use significantly increases risk
Use of smokeless tobacco
GERD
Human Papillomavirus (HPV) (cancers normally seen in oropharyngeal region)

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2
Q

Symptoms

A

Laryngeal Cancer
Persistent hoarseness
Odynophagia
Dysphagia
Dyspnea
General Symptoms
Unexplained weight loss
Ear pain
Enlarged lymph nodes/lumps in the neck which continue to grow
Difficulty breathing
Fatigue
Hemoptysis

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3
Q

Cancer Type

A
  • Squamous cell carcinomas (SCC): Almost 90% of all
    HNC are SCC. Squamous cells that line the moist
    surfaces inside the head and neck regions
  • Adenocarcinomas
  • Sarcomas
  • Melanomas
  • Lymphomas
  • Thyroid cancer types: Papillary (most common),
    medullary cancer (hereditary), anaplastic
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4
Q

Symptoms

A
  • Persistent hoarseness: Glottic tumors
  • Dysphagia
  • Odynophagia
  • Dyspnea
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5
Q

General Symptoms

A
    1. Unexplained weight loss
  • Ear pain
  • Enlarged lymphnodes/ lumps in the neck which
    continue to grow
  • Difficulty breathing
  • Fatigue
  • Hemoptysis
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6
Q

Diagnosis

A
  • Head and neck examination:
    Visually examing all of the structure of oral cavity, pharynx, and larynx
    (endoscopy; stroboscopy)
  • Lymph node palpation: performed by ENT or head and neck surgeon
  • Imaging (CT/MRI/PET) CT: DEPTH
  • Direct laryngoscopy: examination under anesthesia
  • Fine needle aspiration cytology (FNAC)
  • Biopsy: tissue is taken directly from the tumor& FNAC & BIOPSY are only tests that can CONFIRM the presence or absence AND the type of cancer
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7
Q

Staging (TMN Classification)

A

T = primary tumor size and extent
N = absence or presence and extent of regional lymph node metastasis
M = absence or presence of distant metastasis

Lymph node distribution:
* I = submental/submandibular nodes
* II = upper jugulodigastric group
* III = draining the nasopharynx and oropharynx, oral cavity, hypopharynx, larynx
* IV = inferior jugular nodes draining the hypopharynx, subglottic larynx, thyroid, esophagus
* V = posterior triangle group

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8
Q

Staging

chemo/radiation

A

Stage 1 = T1/N0/M0
Stage 2 = T2/N0/M0
Stage 3 = T3/N0/M0, T3/N1/M0
Stage 4 = any T4/N0/M0/, any T2/N2/M0, any T/N3/M0, any T/any N/M1
Automatically considered Stage 4 cancer if T4, T2/N2, N3, or M1

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9
Q

Organ Preservation

A
  • Combination of primary chemotherapy and radiation therapy
  • Aims to preserve the larynx and avoid a permanent stoma
  • Pros: Preserves the larynx, avoids creating a stoma
  • Cons: Severe swallowing and voice issues after high does of chemoradiation
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10
Q

Radiation Therapy

A
  • Pros: Preserves the larynx, avoids creating a stoma
  • Cons: Damages healthy tissue and organs in area, acute/delayed toxicity, xerostomia, mucositis dental caries, dysphonia, dysphagia, hypothyroidism, lymphedema
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11
Q

Conservation Surgeries

A
  • Hemilaryngectomy: vertical removal of laryngeal structures (may involve complete removal of on VF and partial removal of structures on contralateral side)
  • Transoral robotic surgery: includes tongue base, tonsil, and supraglottic masses
    -Pros: minimally invasive procedure, eliminates need for post op tracheostomy, better swallowing, breathing, and voice outcomes
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12
Q

Subsites

A
  1. above glottis- supraglottis= false vf, epiglottis
  2. VF= Glottis
  3. blelow glottis= Subglottis= cricoid, trachea
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13
Q

Hypopharynx

A
  • not apart of the pharynx
  • Piriform sinuses, post cricoid
    region, posterior pharyngeal wall
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14
Q

Radiation Therapy

A

Radiation therapy damages healthy tissue and
organs in the area surrounding the target
* Acute and delayed toxicity
* Vulnerable areas: Oral cavity, skin, thyroid
 Xerostomia, mucositis, dental caries
 Dysphonia/Dysphagia
* Hypothyroidism

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15
Q

Lymphedema

A
  • Lymphedema development
    is the result of injury or
    scarring to the lymph
    vessels or removal of the
    lymph nodes
  • Lymphedema results in an
    accumulation of lymphatic
    fluid in the interstitial
    tissue.
  • Can cause severe swelling
    of the face and neck region
    resulting in discomfort, and
    at times respiratory
    compromise
  • Physical therapy or Lymphede specialized SLP services
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16
Q

LARYNGEAL “CONSERVATION” SURGERY

A
  • Laser excision: Type I to V; depending upon the
    amount of vocal fold resected. Type V cordectomy
    involves a complete removal of the vocal fold.
  • Partial Laryngectomy
  • Supraglottic laryngectomy:
    Involves removal of structures
    above the glottis including the
    epiglottis.

Hemilaryngectomy:
* Involves vertical
removal of
laryngeal structures.
* May involve complete
removal of one vocal
fold and partial removal
of structures on the
contralateral side

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17
Q

TRANSORAL ROBOTIC SURGERY

A
  • Minimally invasive procedure
  • Tongue base, tonsil and
    supraglottic masses.
  • Usually eliminates the need
    for a post op tracheostomy
  • Better swallowing, breathing
    and voice outcomes
18
Q

TOTAL LARYNGECTOMY

A
  • Removal of the entire larynx, including the
    epiglottis, hyoid bone, larynx, and cricoid
    cartilage
  • Neck dissection
  • Thyroidectomy
  • Reconstruction*
  • Salvage laryngectomy: Total laryngectomy
    performed following previous curative intent
    radiation therapy with or without
    chemotherapy
19
Q

TOTAL LARYNGECTOMY: RECONSTRUCTION

A
  • Pectoralis Major Flap
  • Free Flap
  • Radial forearm
  • Jejunal
  • Thigh flap
    Extended procedures: Glossectomy, pharyngectomy,
    esophagectomy
20
Q

FUNCTIONAL IMPLICATIONS

A
  • Loss of original
    sound source
  • Permanently
    altered airway:
    mucous
    management (nasal
    and stoma),
    breathing, snoring,
    sneezing, blowing,
    sipping, coughing
  • Disfigurement
  • Altered olfactory
    and taste sensation
  • Dysphagia and
    digestive problems
  • Alterations in head,
    neck and shoulder
    function/ sensation
  • Alterations in
    lymphatic
    drainage pattern
  • Hypothyroidism
  • Depression
21
Q

PRE-OPERATIVE EXAMINATION

A
  • Oral Mechanism Examination
  • Articulation
  • Brief Cognitive Assessment
  • Current swallowing function
  • Nutritional Status
  • Hearing Acuity
  • Literacy
  • Visual Acuity
  • Physical limitations and support system
22
Q

PRE-OPERATIVE COUNSELING

A
  • Introduce yourself
  • What have you
    heard?
  • How do you learn
    best?
  • Anticipate potential barriers
    to recovery, discharge, learning and the rehabilitative
  • Patients goals?
  • Review basic information
  • Cancer
  • Removalof Larynx
  • Stoma
  • Appearance
  • Estimated
23
Q

POST-OPERATIVE GOALS

A
  • Prepare the patient & family for discharge
  • Suctioning
  • Nutritional Support
  • Nursing
  • Effective Communication
  • Stoma Care Supplies
  • An emergency plan
  • Education and emotional support
  • Evaluation of Swallowing
  • Preliminary communication training
  • Discharge planning and physician orders
24
Q

EDUCATION AND TRAINING

A
  • Laryngectomy Kit
  • Stomam care/pulmonary hygiene
  • Showering
  • Humidification
  • Bowel issues
  • Lifting
  • Smell/taste
  • Tube Feedings
  • Laughing/ crying
  • Snoring/ Coughing/
  • Sneezing
  • Blowing/ Sipping
  • Oral Care
25
OUTPATIENT REHABILITATION
* Pulmonary rehabilitation * Adequate nutritional intake * Altered Olfaction and Taste sensation * Neck and Shoulder Dysfunction * Lymphedema management * XRT care * Emotional support * Communication
26
FACTORS TO CONSIDER: STOMA CARE
* Adequate stoma size * Skin care * Appropriate protective coverings * Stoma covers * HME’s * Mucous management * Emergent medical care issues
27
HME: HEAT MOISTURE EXCHANGER
* Disconnect between upper and lower airways resulting in the loss of humidification, cleaning and moisturizing of inhaled air through the nose * HME: Provides humidification in patients with tracheostomy: Not limited only to laryngectomy patients * HME sits over the stoma heating and moistening it in the process. * Contains foam treated with calcium chloride. As the person breathes out, the foam collects and saves humidity and warm air * The goal is to approximate the temperatures and relative humidity at the nasal level pre-surgery, to the temperature levels at the trachea, post-surgery
28
VOICE REHABILITATION
* Artificial larynx * Tracheoesophageal speech * Esophageal speech * Selection of most functional communication method * Communication training * Ongoing communication maintenance and upkeep
29
ARTIFICIAL LARYNX TRAINING
Parameters of AL speech * Handedness * Placement * On/off device activation * Articulation strategies * Distractors * Pragmatics * Device Maintenance* Training hierarchy * Sounds * Words * Phrases * Sentences * Conversational speech * Prosodic features: pitch, emphasis, intensity
30
ARTIFICIAL LARYNX TRAINING
Advantages * Generally easy to learn. * Equal in intelligibility to esophageal speech * More easily discriminated in noise than is esophageal speech * Can be easily adapted and changed to an intraoral device. Disadvantages * Robotic quality * Cost factor * Requires use of one hand for operational use * Failure for mechanical breakdown * Difficult to vary and use the pitch variation features * Limited ability to
31
PHARYNGOESOPHAGEAL (PE) SEGMENT
* It is the sound generator for individuals using esophageal speech or tracheoesophageal speech. The tonicity of the PE segment greatly influences voice quality. * Diedrich (1968) used the term “pharyngesophageal” to describe the anatomical region used for the generation of post laryngectomy voice source. * The source of esophageal phonation is primarily derived through response of the cricopharyngeus muscle. * The cricopharyngeus muscle is best described as a band of muscle located in the transitional region between the lower pharynx and the upper esophagus
32
ESOPHAGEAL SPEECH
 Phonatory source or sound generator is the PE segment.  Esophageal speech is based on the technique in which the patient transports a small amount (±75 ml) of air into the esophagus. Two major methods of air intake: Inhalation: Esophagus is in a state of negative pressure and as air is inhaled into the lungs, air also enters the esophagus. Air pressure in the lungs and esophagus become equalized. Air can then be expelled to produce vibration of the PE segment. Injection (glossopharyngeal press and plosive injection) : Compressing the intraoral air into the esophagus with assistance from the tongue or lips and sometimes the cheeks.
33
TRACHEOESOPHAGEAL SPEECH
What is a TE-Puncture? * Fistula created between trachea and the esophagus * A device/prosthesis made of medical grade silicone is positioned within the “party wall” * The prosthesis allows air to be shunted from the lungs into the esophagus * Vibration of the tissue in the lower pharynx serves as the new sound source
34
TRACHEOESOPHAGEAL SPEECH 2
* Primary or secondary procedure for the purpose of voice restoration. * Primary TEP: The TE fistula or puncture is created at the time of the total laryngectomy (more common). * Secondary TEP: The TE fistula or puncture is created months or at times years after the total laryngectomy. * Voice restoration is more successful after primary TEP* * Creation of a tracheoesophageal (TE) fistula between the trachea and the esophagus in the superior border of the stoma.
35
CANDIDACY
* Generally Healthy * Functional anatomy  Stoma  Neopharynx  Esophagus * Adequate pulmonary support * Functional cognitive status, visual acuity and manual dexterity * Social Support * Reasonable expectations
36
TE SPEECH
Advantages * Pulmonary air as the driving force for the PE segment. This allows the patient to sustain phonation over a longer period of time. * Provides a more natural speech-breathing action and the acoustic, characteristics of voice (intensity, frequency, and rate) are closer to approximate measures for laryngeal speakers. * TE speech is easy to acquire and learn. * Hands-free prosthesis Disadvantages * Daily maintenance of the prosthesis by the patient. * Semi-permanent: Prosthesis needs to be changed regularlyUsually every 3 months. * The recurrent leakage of the prosthesis after a period of time and therefore required replacement by the clinician. * if performed as a secondary procedure, requires additio
37
CONTRAINDICATIONS
* Inadequate pulmonary reserve: Hx of COPD, emphysema, pulmonary fibrosis, interstitial lung disease, * Inadequate depth and diameter of stoma to accept prosthesis without airway compromise * Recurrent Disease * Unresolved fistula * “Bad” Tissues * Reduced Income * Poor or No Insurance * Transportation Issues
38
PE SPASM: TREATMENT
* BOTOX: Relieves the cricopharyngeal spasm. May or may not require multiple injections over time (Senchuk, 2010) * Pharyngeal neurectomy- Performed to avoid myotomy and consequent swallowing issues. Efficacy with regards to spasm relief is variable (Singer, et al.1986) * Cricopharyngeal myotomy- Associated with formation of pharyngocutaneous fistula (at the time of laryngectomy). However, successful in restoring TE-speech if BOTOX fails (Hamaker, 2003) * Mechanical dilation: Relieves dysphagia, less successful in restoring TE-speech (Chao et.al
39
TREATMENT: PE-SPASM ## Footnote botox
BOTOX: * Most extensively researched, clinically * Systematic review (Senchuk, 2010): Improved voice and swallowing outcomes, need for re-injection was variable across studies, dosage was variable across studies, EMG guided/non-EMG guided, videofluoroscopy
40
CONCLUSIONS
* Offer options not opinions * Advocate for patients but more importantly teach them to advocate for themselves * Encourage patients to take advantage of community support * Encourage independence * Develop/maintain a good working relationship with physicians and other professionals * Support the patients right to choose