Heart Failure Flashcards

(50 cards)

1
Q

systolic dysfunction

A

Impaired contractility that leads to a decreased ejection fraction

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2
Q

Diastolic dysfunction

A

Impaired ventricular filling during diastole due to either impaired relaxation or increased stiffness of the ventricle or both

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3
Q

“High Output” HF

A

Increase in CO is needed for the requirements of peripheral tissues for oxygen

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4
Q

Pathologic S3 (ventricular gallop)

A

Sound of Rapid filling phase into a non-compliant LV

*among most specific signs of CHF

Heard best at apex with bell
S3 follows S2 “Ken-tuck-Y”

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5
Q

S4 Gallop

A

Sound of atrial systole as blood ejected into a non-compliant or stiff LV

Heard best a left sternal border
s4 precedes s1 “TEN-nes-see”

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6
Q

Increased intensity of pulmonic component of second heart sound indicates……

A

Pulmonary Hypertension

Heard over left upper sternal border

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7
Q

NYHA Class I

A

Symptoms only occur with vigorous activity (like playing a sport)

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8
Q

NYHA Class II

A

Symptoms with prolonged or moderate exertion (like climbing stairs)
Slight limitations of activities

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9
Q

NYHA Class III

A

Symptoms occur with usual activities of daily living (Walking across a room)
Markedly limiting

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10
Q

NYHA Class IV

A

Symptoms occur at rest

Incapacitating

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11
Q

ACC/AHA HF Stage A

A

Risk factors present for HF, but have no structural heart disease or symptoms

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12
Q

ACC/AHA HF Stage B

A

Structural heart disease without HF

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13
Q

ACC/AHA HF Stage C

A

Structural heart disease with HF symptoms (prior or current)

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14
Q

ACC/AHA HF Stage D

A

Refractory HF requiring specialized interventions

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15
Q

Signs and symptoms of left-sided HF

A

“Lung Symptoms”

Dyspnea
Orthopnea
Paroxysmal Nocturnal Dyspnea
Nocturnal Cough
Pulmonary Hpertension
S3 and S4 sounds present
Crackles/rales
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16
Q

Signs and symptoms of Right-sided HF

A

“Backed up veins” Symptoms

Peripheral pitting edema
Nocturia
JVD 
Hepatomegaly 
Hepatojugular Reflex
Ascites
RV Heave
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17
Q

Tests to order for new patient with CHF

A

CXR (pulmonary edema, cardiomegaly, r/o COPD)
ECG
Cardiac Enzymes (r/o MI)
Echocardiography (estimate EF, r/o pericardial effusion)

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18
Q

Paroxysmal nocturnal dyspnea

A

Awakening after 1-2 hours of sleep due to SOB

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19
Q

Nocturnal cough is worse in what position?

A

Recumbent (same pathophysiology as orthopnea)

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20
Q

From where and why is brain natriuretic protein (BNP) released?

A

Released from ventricles in response to ventricular volume expansion and pressure overload

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21
Q

What BNP levels correlate strongly with presence of decompensated CHF?

A

levels >150 pg/mL, but remember you must compare this to the patient’s baseline or usual BNP levels, because they may be consistently elevated in CHF

22
Q

Though not used to diagnose CHF, why can BNP be useful?

A

Can help differentiate between dyspnea caused by CHF and COPD

23
Q

What NT-proBNP value virtually excludes diagnosis of CHF?

24
Q

Compare potency of diuretics used in CHF patients

A

Loop diuretics (furosemide) most potent

Thiazide diuretics (hycrochlorothiazide) modestly potent

25
What CHF stages is spironolactone effective in?
Advanced stages Classes III and IV
26
What is an alternative to spironolactone and when would it be used?
Eplerenone can be used if spironolactone causes gynecomastia
27
Contraindication of spironolactone
Renal Failure
28
Standard treatment of CHF includes
Loop diuretic ACE inhibitor Beta Blocker
29
All patients with systolic dysfunction even if asymptomatic should be on....
ACE Inhibitor
30
If ACE inhibitor can not be tolerated what are some alternatives?
Angiotensin II Receptor Blockers (ARBs) Hydralazine and Isosorbide dinitrates
31
Common side effect of the ACE inhibitors
Cough (non-productive)
32
Beta blockers should be given to what kind of CHF patients?
Must be STABLE (class I, II, III)
33
Which beta blockers have evidence for efficacy in CHF?
Carvedilol (shown to be most effective) Metoprolol Bisoprolol
34
What is the most common cause of death in CHF?
Sudden death from ventricular arrhythmia Ischemia can provoke these
35
Digoxin is useful in patients with....
EF
36
Hydralazine and isosorbide dinitrates have been shown to improve mortality in which selected patient population?
African Americans
37
Medications contraindicated in CHF
Metformin: may cause lethal lactic acidosis Thiazolidinediones: cause fluid retention NSAIDs: increase risk of CHF exacerbation Some antirhythmics with negative inotropy
38
Medications shown to decrease mortality in systolic HF
ACE inhibitors and ARBs Beta Blocers Aldosterone antagonists (spironolactone/eplerenon) Hydralazine + nitrate
39
Medications that do not decrease mortality in HF but provide symptomatic relief
Digoxin | Diuretics
40
What are signs of Digoxin toxicity
GI: N/V, anorexia Cardiac: Ectopic (ventricular) beats, AV block, AFib CNS: visual disturbances, disorientation
41
which devices have been proven to decrease mortality in CHF patients?
Implantable Cardioverter Defibrillator and Cardiac Resynchronization therapy (biventricular pacemaker)
42
Treatment of Diastolic Dysfunction
Treated symptomatically No meds have been proven to have mortality benefit Use beta blockers and diuretics
43
Which meds should NOT be used in diastolic dysfunction
Digoxin | Spironolactone
44
What is acute decompensated HF?
Acute dyspnea associated with increased left-sided filling pressures with or without pulmonary edema
45
What is decompensated HF most commonly due to?
Dietary indiscretion
46
"Flash Pulmonary Edema"
Severe form of HF with rapid accumulation of fluid in the lungs
47
What is the most important intervention in acute decompensated HF?
Diuretics to treat volume overload and congestive symptoms
48
Why is digoxin not indicated in acute decompensated HF?
Because it takes several weeks to work
49
Which implantable device should be used in CHF NYHA class II-III?
Implantable Cardiac Defibrillator
50
Which implantable device should be used in CHF NYHA class III-IV with QRS >120 ms?
Cardiac Resynchronization Therapy