Heart Morphogenesis Flashcards
(15 cards)
Are the 5 phases of heart morphogenesis
- Cardiac looping
- Atrial septation
- Ventricles septation
- Outflow tract formation
- Valve development
First part of the atrial septation
Septum Primum narrows foramen primum
Second part of the atrial septation
Foramen secundum appears in the septum primum while the foramen primum disappears
Third part of the atrial septation
Apparition of the septum secundum
Fourth part of the atrial septation
Growing of septum secundum and foramen secundum turns into foramen ovale
Fifth part of the atrial septation
Residual septum primum turns into the valve of foramen ovale
Sixth part of the atrial septation
Fusion of both septums (primum and secundum)
Seventh part of the atrial septation
Foramen ovale closes in the birth (increase of left atrium pressure and decreased right atrium pressure)
First part of ventricle septation
Formation of interventricular septum and foramen
Second part of the ventricle septation
Rotation and fusion of the aorticopulmonary septum with the ventricular septum -> closing the interventricular foramen
Third part of the ventricle septation
Growth of endocardial cushions, separating the atria from ventricles, atrial septation and membranous portion of interventricular septum
Explain the outflow tract formation
The neural crest and endocardial cells migrates
Truncal and bulbar ridges that spiral and fuses, forming aorticopulmonary septum
Is the result of the outflow tract formation
A separated ascending aorta and pulmonary trunk
Which valves are derivated from the endocardial cushions of the outflow tract
Aortic and pulmonary
Which valves are derivated from the endocardial cushions of the AV canal
Mitral and tricuspid
