Helix-Coil Transitions in Polymers Flashcards
1
Q
driving force for protein folding
A
hydrophobicity, shield hydrophobic parts from the solvent
2
Q
why are attractive dipole interactions favoures
A
molecules don’t rotate freely at a finite temp
3
Q
denaturation due to
A
temp, solvent, pH or reactions with denaturants
4
Q
unwinding helix to coil
A
cooperative transition, polymer becomes increasingly more susceptible to transformational changes once the process has begun
5
Q
allowed conversion
A
conversion from h to c allowed if residue adjacent to one undergoing transition is already a c residue
6
Q
nucleation step
A
first step, less favourable than the remaining conversions
7
Q
what does smaller nucleation parameter mean in curve shape
A
harder to get coil formation started = sharper transition
