Helminths (Superfamily Metastrongyloidea) Flashcards

Georgi's (58 cards)

1
Q

What are Metastrongyloids?

A

Parasites of the respiratory, vascular, and nervous systems of mammals

Most species require a snail or slug intermediate host, but some can infect directly.

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2
Q

In which family is the genus Metastrongylus found?

A

Family Metastrongylidae

Contains large white parasites of the bronchi and bronchioles of swine.

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3
Q

What is the characteristic of the mouth in Metastrongylus?

A

Flanked by a pair of trilobed lips

The spicules are long and thin.

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4
Q

What type of eggs do oviparous females of Metastrongylus lay?

A

Eggs containing first-stage larvae

These eggs typically do not hatch without being ingested by an earthworm.

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5
Q

What is the economic and pathological importance of Metastrongylus spp.?

A

Of only modest importance

They were once thought to act as vectors for swine influenza virus, but proof is lacking.

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6
Q

Name three approved anthelmintics for swine lungworms.

A
  • Fenbendazole
  • Levamisole
  • Ivermectin

Doramectin is also approved.

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7
Q

What is a key identification feature of Protostrongylids?

A

Well-developed bursa, spicule, and spicule guide

The vulva is also near the anus.

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8
Q

What type of eggs do oviparous protostrongylid females deposit?

A

Unsegmented eggs in surrounding lung, vascular, or neural tissues

These develop into first-stage larvae before appearing in feces.

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9
Q

Where does Protostrongylus rufescens live?

A

In the smaller bronchioles of sheep and goats

It may cause localized lesions.

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10
Q

What is the treatment for M. capillaris infection in sheep?

A

Moxidectin (1% injectable solution at 0.2 mg/kg)

In goats, topical eprinomectin (0.5 mg/kg) is used.

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11
Q

What is the typical host for Parelaphostrongylus tenuis?

A

White-tailed deer (O. virginianus)

It rarely causes disease in this species.

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12
Q

What type of signs indicate Parelaphostrongylus tenuis infection in abnormal hosts?

A

Neurologic signs

This can lead to serious or fatal disease.

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13
Q

What is the identification feature of Crenosomatidae?

A

Well-developed bursae with a large dorsal ray

The uterus is amphidelphic with a prominent ovijectoral sphincter.

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14
Q

What is the life history of Crenosoma vulpis?

A

Oviparous females deposit first-stage larvae or thin-shelled eggs containing them

These develop into infective third-stage larvae in snails and slugs.

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15
Q

What is a successful treatment for Crenosoma vulpis infection in dogs?

A

Fenbendazole (50 mg/kg daily for 3 to 7 days)

A single treatment with milbemycin oxime was also effective.

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16
Q

What characterizes the family Angiostrongylidae?

A

The bursa may be somewhat reduced, but rays are well defined

The vulva is near the anus, and the uterus is prodelphic.

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17
Q

What is a key feature of Aelurostrongylus abstrusus?

A

Oviparous female deposits unsegmented eggs in ‘nests’ in lung parenchyma

These appear as small, grayish white subpleural nodules.

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18
Q

How do cats typically become infected with Aelurostrongylus abstrusus?

A

Predation of paratenic hosts that consume snails

Mice and possibly birds may serve as paratenic hosts.

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19
Q

What percentage of cat fecals were found positive for Aelurostrongylus abstrusus in a survey?

A

6.2% of 1322 cat fecals

This was from shelters in upstate New York.

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20
Q

What percentage of cat fecals from shelters in upstate New York were found positive for A. abstrusus?

A

6.2%

Based on a study conducted by Lucio-Forster and Bowman in 2011.

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21
Q

What was the prevalence of A. abstrusus found in a national survey of feline fecal samples examined at IDEXX Laboratories from 2008-2017?

A

0.15%

This prevalence was primarily observed in the Northeast, Great Lakes area, and West Coast.

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22
Q

What geographic factor was noted in the antibody detection assay for A. abstrusus in Switzerland?

A

90.3% of positive cats were from elevations below 700 meters above sea level

98.9% were from areas with mean temperatures above –2°C in January.

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23
Q

What clinical signs may be associated with moderate A. abstrusus infection?

A

Coughing and anorexia

Severe infections can lead to cough, dyspnea, and polypnea.

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24
Q

What percentage of cats that died during a spay-neuter program in New York State were found infected with A. abstrusus?

A

9%

This was determined during necropsy examinations.

25
What treatment was successfully used for A. abstrusus infection according to Kirkpatrick and Megella (1987)?
A single parenteral dose of ivermectin (0.4 mg/kg) ## Footnote However, success varied in other cases.
26
What treatment modality resulted in successful resolution in a cat infected with A. abstrusus in Germany?
Topical selamectin (6 mg/kg) administered one month apart ## Footnote This treatment was successful, but failed in other cases in Italy.
27
What is the prepatent period for Angiostrongylus vasorum?
Around 7 weeks
28
What are some clinical signs associated with Angiostrongylus vasorum infections?
Lung disease, clotting disorders, subcutaneous hemorrhages, intracranial hemorrhage ## Footnote These can manifest in severe cases.
29
How were the 16 dogs diagnosed with Angiostrongylus vasorum in Newfoundland treated?
Four weekly oral doses of 0.5 mg of milbemycin oxime per kilogram ## Footnote Most showed resolution of clinical signs.
30
What type of treatment is primarily used for Angiostrongylus cantonensis?
Supportive treatment with immunosuppression ## Footnote This is to prevent reaction to migrating worms.
31
What symptoms can arise from A. cantonensis infection in mammals?
Eosinophilic meningitis and encephalomyelitis ## Footnote This occurs if infected snails or paratenic hosts are ingested.
32
What are the first-stage larvae of A. costaricensis found in?
The feces of rodents ## Footnote Snails serve as intermediate hosts.
33
What are the common symptoms of A. costaricensis infection in humans?
Pain in the lower right abdomen, fever, vomiting
34
What distinguishes the Filaroididae family from other Metastrongyloidea worms?
They are without a bursa ## Footnote This family contains species that use snail intermediate hosts.
35
Where do adult Filaroides osleri occur in infected dogs?
In nodules in the trachea and bronchi
36
What is a characteristic feature of the body cuticle of Filaroididae worms?
It is inflated to form a diaphanous teguminal sheath
37
What is the body cuticle inflated to form?
A diaphanous teguminal sheath.
38
Where does Filaroides osleri occur in dogs?
In nodules within the epithelium of the trachea and bronchi.
39
What type of eggs do female Filaroides osleri deposit?
Delicate, thin-shelled eggs containing first-stage larvae.
40
How is F. osleri infection acquired?
Through ingestion of regurgitated stomach contents, lung tissue, or feces of infected dogs.
41
Who was the first to transmit F. osleri infection to dogs?
John Dorrington.
42
What is a hypothesized method of transmission of F. osleri from bitches to their pups?
Salivary contamination during licking.
43
How long does it take for nodule formation to be detected in F. osleri infection?
About 2 months.
44
What common symptom is associated with F. osleri infection?
Spasmodic attacks of a hard, dry cough.
45
What criteria indicate successful chemotherapy of F. osleri infection?
* Disappearance of cough and air hunger on exercise * Resolution of tracheal and bronchial nodules * Cessation of fecal larval output.
46
What treatments have been used for F. osleri infection?
* Fenbendazole * Ivermectin * Doramectin.
47
What is the dosage of fenbendazole reported to stop coughing in a dog with F. osleri?
50 mg/kg daily for 7 days.
48
What is unique about Filaroides hirthi's infective stage?
It is infective in the first larval stage and requires no period of development outside the host.
49
How does F. hirthi primarily transmit among puppies?
Through ingestion of first-stage larvae in freshly passed feces.
50
What is a consequence of F. hirthi in research dogs?
It interferes with the interpretation of toxicologic experiments.
51
How is F. hirthi infection usually diagnosed?
By demonstration of first-stage larvae in the feces.
52
What treatment is highly effective for F. hirthi infection?
Albendazole at a dosage of 25 mg/kg body weight twice daily for 5 days.
53
What dosage of ivermectin was shown to reduce F. hirthi infection in treated dogs?
1 mg/kg subcutaneously administered once or twice at a week apart.
54
True or False: F. hirthi infection is always attended by clinical signs of disease.
False.
55
What happens to first-stage larvae after oral infection with F. hirthi?
They arrive in the lungs as early as 6 hours.
56
Fill in the blank: Filaroides osleri develops slowly with nodule formation detectable by _______.
bronchoscope.
57
What is the typical outcome of severe F. hirthi hyperinfection in stressed animals?
Fatal cases have developed.
58
What was reported about the efficacy of fenbendazole for F. hirthi infection?
It did not clear a dog of its F. hirthi infection.