Hema 1 Part 2.1

Question 1

HOWELL JOLLY BODIES seen in

Answer 1

→ Megaloblastic anemia

Question 2

Heinz bodies seen in

Answer 2

Lead poisoning and G6PD

Question 3

PAPPENHEIMER BODIES seen in

Answer 3

Sideroblastic anemia

Question 4

BASOPHILIC STIPPLING seen in

Answer 4

Condition/s:
→ Lead poisoning / intoxication
→ Pyrimidine-5-nucleotidase
deficiency

Question 5

CABOT RINGS seen in

Answer 5

Megaloblastic anemia

Question 6

HEMOGLOBIN CRYSTALS seen

Answer 6

cells
→ Condition/s:
▪ Thalassemia
▪ Hemoglobinopathy
− FINDINGS: Target cells
+ Hgb SC

Question 7

POLYCHROMASIA seen in

Answer 7

Retics

Question 8

• Bi-lobed, showing pince-nez
appearance
• Hyposegmentation

Answer 8

PELGER-HUET ANOMALY

Question 10

• May be seen with macro
ovalocytes around the red cells

Answer 10

Hypersegmentation

Question 11

• Thickened, enlarged granules
ONLY in Neutrophils
→ Can be accompanied by
vacuolation
• Most common

Answer 11

Toxic granulation

Question 12

GAUCHER CELL seen in

Answer 12

Glucocerebrosidase
deficiency or Gaucher Disease

Question 13

FOAM CELL seen in

Answer 13

Niemann-Pick Disease

Question 14

• Marginates / indent with the
surrounding RBCs
• The cell membrane adjusts to the
surrounding RBCs

Answer 14

ATYPICAL / VARIANT / REACTIVE LYMPHOCYTE / DOWNEY CELLS /
TURK’S IRRITATION CELL

Question 15

Lymphocytes that are larger than
usual

Answer 15

SEZARY CELLS

Question 17

Multinucleated giant cell with
OWL’S EYE appearance

Answer 17

REED-STERNBERG CELLS

Question 18

REED-STERNBERG CELLS seen in

Answer 18

Hodgkin’s lymphoma

Question 19

Supravital stains:

Answer 19

→ New methylene blue
→ Brilliant cresyl blue
→ Crystal violet

Question 20

May be used to aid in counting reticulocytes

Answer 20

MILLER DISC

Question 21

CORRECTED RETICULOCYTE COUNT
• Used to correct the reticulocyte counts in patients with

Answer 21

anemia

Question 22

Hemoglobin iron content = _____of hemoglobin

Answer 22

0.347%

Question 23

Hemoglobin that contains iron in the ferric stat

Answer 23

METHEMOGLOBIN

Question 24

Will cause chocolate brown discoloration of blood

Answer 24

METHEMOGLOBIN

Question 25

• Will cause CHERRY RED discoloration of blood • has 200-245x more affinity to hemoglobin compared to O2

Answer 25

CARBOXYHEMOGLOBIN

Question 26

Cannot bind or carry oxygen; reversible

Answer 26

CARBOXYHEMOGLOBIN

Question 27

• Results when sulfur is incorporated in the heme rings of hemoglobin • Causes MAUVE LAVENDER discoloration of blood

Answer 27

SULFHEMOGLOBIN

Question 28

Cannot bind or carry oxygen; Irreversible; Not detected by the cyanmethemoglobin method

Answer 28

SULFHEMOGLOBIN (SHB)

Question 29

Also known as PACKED RED CELL VOLUMES

Answer 29

Hematocrit

Question 30

Hematocrit • Expressd in conventional unit: • SI unit:

Answer 30

• Expressd in conventional unit: % • SI unit: L/L ( liter per liter)

Question 31

ADAM’S MICROHEMATOCRIT Centrifugation speed and time

Answer 31

• Speed – 10,000 to 15,000 x gravity • Time – 5 minutes

Question 32

WINTROBE’S MACROHEMATOCRIT centrifugation

Answer 32

Centrifugation: → Speed: 2,000 – 2,300 x gravity (Barbara Brown) → Time: 30mins

Question 33

Overanticoagulation of hematocrit mah lead to

Answer 33

Falsely decreased hematocri

Question 34

Trapped plasma in hemtocrit may lead to

Answer 34

False increased hematocrit → Caused by poikilocytes

Question 35

Length of westergren

Answer 35

300mm

Question 36

Length of wintrobe

Answer 36

115 mm

Question 37

Internal bore of westergren

Answer 37

2.65mm

Question 38

External bore of westergren

Answer 38

5.5mm

Question 39

Internal bore of wintrobe

Answer 39

3.0mm

Question 40

Westergren graduation lines

Answer 40

200 mm

Question 42

Graduation marks of wintrobe

Answer 42

100mm

Question 43

Zeta sedimentation rate • Special capillary: → ____long → ____ inner diameter → ____ outer diamete

Answer 43

→ 75mm long → 2.0mm inner diameter → 2.3mm outer diamete

Question 44

Zeta sedimentation rate is filled _____with well mixed EDTA-anticoagulated whole blood_______

Answer 44

is filled (3/4 full) with well mixed EDTA-anticoagulated whole blood (approx. 0.2 ml)

Question 45

AUTOMATED ESR SYSTEMS • Include:

Answer 45

→ Ves-Matic → Mini-Ves → Sedimat

Question 46

Automated ESR system TAT

Answer 46

Can give results in 15 to 20 minutes