Hema 4 Part 3 - THROMBOCYTOSIS

Question 1

Thrombocytosis, platelet reference range

Answer 1

140-440x109/L

Question 2

Primary thrombocytosis disorder

Answer 2

5-q syndrome

Question 3

primary thrombocytosis is usually with ___/___ plateletes

Answer 3

large or giant platelets

Question 4

Mutation of the gene controlling TPO

Answer 4

Familial Thrombocytosis

Question 5

Platelet count at elast 600x109/L, ussually >1000x109/L with hypogranular contents

Answer 5

Myeloproliferative disorders especially ET

Question 6

Secondary thrombocytosis - reactive disoders

Answer 6

increased IL-6
anemia; IDA, HA
acute blood loss
surgery
chronic inflammatory disease
kawasaki disease