Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Board Exam > Hema > Flashcards

Hema Flashcards

(93 cards)

Start Studying
1
Q

In an electronic cell counter, a falsely elevated hematocrit was obtained. Which would be affected? (3)

A

MCV
MCHC
RDW

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Derived from RBC histogram (2)

A

MCV

RDW

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Derived from WBC histogram

A

MPV

PDW

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Calculated from measured and derived values

A

Hematocrit
MCH
MCHC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Small cell with curve nucleus with more than 1/2 nuclear indentation. With presence of granules, cytoplasm is pale blue to light violet, there is low nucleus:cytoplasmic ratio

A

Band cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Pathway of G6PD deficiency

A

Hexose Monophosphate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Most common problem in cell counting. It causes and increase in current and particles in lower threshold limit will be counted

A

Aperture plug

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

15 Codocytes/OIF were seen, the correct manner of reporting is

A

+2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Seen in Megaloblastic anemia (3)

A

Vitamin B12 deficiency
Folate deficiency
Vitamin B9 deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Representation in x-axis (2)

A

Horizontal and Independent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Effect of microcytosis in platelet count using Hematology analyzer

A

Spurious increase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

FAB classification in Acute Megakaryocytic Leukemia

A

M7

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Appearance of Pelguer-Huet anomaly

A

Pinz-nez

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Composed of ribosomal RNA, associated with WBC anomaly which is seen in infection, burns and pregnancy

A

Dohle bodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Inclusion body seen in lead poisoning

A

Basophilic stippling

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

RBC less than 6um

A

Microcytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

RBC greater than 8um

A

Macrocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Causes of underfilled tube (3)

A

Blood flow stopped
Minimal vacuum inside the tube
The tube was uncapped

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Tests use to determine PNH (3)

A

Sucrose Hemolysis test
Sugar Water test
Acid Serum test

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Causes positive instrumental errors (3)

A

Aperture plugs
Bubbles
Electrical pulses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Found in organelle zone (4)

A

Alpha granules
Dense granules
Mitochondria
Lysosomal granules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Slightly decrease in platelet count

A

150,000-299,000/uL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Measured in 3 part differential hematology analyzer

A

Granulocyte
Monocyte
Lymphocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Measured in 5 part differential hematology analyzer

A 
Neutrophil
Eosinophil
Basophil
Monocyte
Lymphocyte
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Lifespan of thrombocyte
10 days
26
Life span of erythrocyte
120 days
27
Formation of platelet plug is seen in
Primary Hemostasis
28
Formation of fibrin clot is seen in
Secondary Hemostasis
29
Reliable criterion to differentiate mature cells from immature cells
Nuclear chromatin
30
Vitamin K dependent factors (4)
“1(0)972”
31
Other name of Prekallekrein
Fletcher factor
32
Extramedullary site for blood production
Liver
33
D dimer positive in DIC as soon as
4 hours
34
Result of platelet retention in Multiple Myeloma
Reduced
35
RBC pathway that generates 2,3-DPG
Rapaport-Leubering pathway
36
RBC pathway that generates ATP
Embden-Meyerhoff pathway
37
Other name of Embden-Meyerhof pathway
Anaerobic Glycolytic Pathway
38
Effect of overanticoagulation in ESR
Decreased
39
Dilution to be used if WBC count is <3.0 x 10^9/L
1:10 or 1:11
40
Dilution to be used if WBC count is 100-300 x 10^9/L
1:200 or 1:201
41
Dilution to be used if WBC count is >30 x 10^9/L
1:100 or 1:101
42
Euglobulin clot lysis time serves as
Screening test
43
Used to differentiate Acute Myelogenous leukemia and Myelomonocytic leukemia from ALL
Sudan Black B
44
Used to differentiate Acute Myelogenous leukemia and Monocytic leukemia from ALL
Peroxidase
45
Is an appendage found on the outer surface of platelets
Glycocalyx
46
Stage where DMS (Demarcating Membrane System) is first formed
Promegakaryocyte
47
A condition with increase peripheral platelet destruction. It has decreased platelet count and increased MPV
Immune Thrombocytopenic Purpura
48
A macrophage monocyte defect in storage function in which accumulation of this metabolite will lead to damage or diminish metabolic activities
Hemochromatosis
49
Myeloid leukemia without differentation
M1
50
Presence of Philadelphia chromosome
Chronic Myelogenous Leukemia
51
Conditions where there is dimorphic RBC population (2)
Sideroblastic anemia | Iron deficiency anemia after iron therapy/transfusion
52
Mature form of B cell (2)
Plasma cell | Memory cell
53
Large lymphocyte with cytoplasmic globules containing immunoglobulins that can sometimes form a grape like pattern
Plasma cell
54
Factor 8 deficiency
Hemophilia A
55
Factor 9 deficiency
Hemophilia B
56
Factor 11 deficiency
Hemophilia C/ Rosenthal Syndrome
57
MCHC is computed using (2)
Hemoglobin | Hematocrit
58
Appearance of Charcot Leyden crystal using Wright stain
Red, spindle shaped
59
Affects PT and PTT levels
200mg/dL of fibrinogen
60
▪️Autosomal dominant trait ▪️Characterized by decreased segmentation of the nucleus of granulocytes ▪️Coarseness and condensation of the nuclear chromatin in the granulocytes, lymphocytes and normoblasts ▪️Most frequently seen in heterozygous state, where less than 40% of neutrophils contain single lobed nucleus
Pelger Huet anomaly
61
These changes are more evident in neutrophil, basophil and eosinophil where the nuclei will appear round, dumbbell shaped (“pinz-nez” appearance) or peanut shaped
Pelger Huet anomaly
62
Affects primarily infants and is due to deficiency in sphingomyelinase that causes an accumulation of sphyngomyelin
Niemann pick disease
63
Affected when plasma is stored
Factor 8
64
In performing venipuncture, anchor vein with thumb _______ inches before the site, and inserting needle, bevel ______, with a ________ degree angle between the skin and the needle
1 to 2 Up 15 to 30
65
Myeloperoxidase positive (4)
``` LANE Leukemic blasts in FAB M1, M2, M3 Auer rods Neutrophilic granulocytes (except normal blasts) Eosinophils ```
66
Myeloperoxidase positive/negative (1)
Monocytes
67
Myeloperoxidase negative (4)
Myeloblasts Lymphocyte cell series Basophils Erythrocytic cell series
68
DiGuglielmo’s syndrome (Erythroleukemia/ Erythremic myelosis)
M6
69
Both an in vivo and in vitro anticoagulant
Heparin
70
Production of primary / non specific / azurophilic granules starts in
Promyelocyte
71
Production of secondary / specific granules starts in
Myelocyte
72
Production of tertiary granules starts in
Metamyelocyte
73
Decreased in Coumadin (Vitamin K) therapy (4)
7 ➡️ 10 ➡️ 9 ➡️ 2 | “1(0)972”
74
In making peripheral blood smears, this will produce uniform distribution of cells
Cover slip technique
75
Appear as rods or cigars
Elliptocytes
76
True regarding ESR (4)
▪️Proportional to the weight of cell aggregate ▪️Inversely proportional to the surface area ▪️Microcytes and irregularly shaped cells (ex. Sickle cell) = lower ESR ▪️Macrocytes and rouleaux formation = higher ESR
77
Inhibits platelet activation by blocking cyclooxygenase (3)
Acetaminophen Aspirin (Acetyl Salicylic Acid) Ibuprofen
78
Proper execution of preparing smear using manual wedge technique
Smooth and Rapid
79
Still viable for evaluation on air dried smears stored at cool temperature in the dark for 2 weeks
Esterase
80
Decrease pressure Increase angle Increase speed Increase size of blood drop
Thick smear
81
Increase pressure Decrease angle Decrease speed Decrease size of blood drop
Thin smear
82
Bone marrow malignancy
Myeloma
83
Anticoagulated microhematocrit
Red
84
Non anticoagulated microhematocrit
Blue
85
D shaped immature cell and it is the last cell capable of mitosis
Myelocyte
86
Top layer in spun hematocrit
Fatty layer
87
Second layer in spun hematocrit
Plasma
88
Third layer in spun hematocrit
Buffy coat (platelets and WBCs)
89
Fourth layer in spun hematocrit
Packed red blood cells
90
Fifth layer in spun hematocrit
Sealant (4 to 6 mm)
91
Gower I hemoglobin
2 zeta, 2 epsilon
92
Gower II hemoglobin
2 epsilon, 2 alpha
93
Portland hemoglobin
2 zeta, 2 gamma

Board Exam (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions