HEMA LEC (OVERVIEW)

Question 1

Red blood cell (RBC) also called

Answer 1

erythrocyte

Question 2

White blood cell (WBC) or ___

Answer 2

leukocyte

Question 3

Platelet or ___

Answer 3

thrombocyte

Question 4

• Study of blood cells

Answer 4

Hematology

Question 5

Red blood cells are (ABDC)

Answer 5

Anucleate, biconcave, discoid cells

Question 6

Size of RBC

Answer 6

6 to 8 um

Question 7

it is Filled with ____, ____

Answer 7

reddish protein,
Hemoglobin (Hgb)

Question 8

transports
oxygen (O2) and carbon
dioxide (CO2)

Answer 8

Hemoglobin

Question 9

Normal RBC count for male

Answer 9

4.20 - 6.0 x106/uL

Question 10

Normal RBC count for female:

Answer 10

3.80 - 5.20 x106/uL

Question 11

RBC count to detect ____ or ____

Answer 11

anemia or
polycythemia

Question 12

loss of
_____ ;
reflected in reduced RBC
count or decreased
hemoglobin concentration

Answer 12

Anemia, O2-carrying capacity

Question 13

increased
RBC count; results to
_____

Answer 13

Polycythemia, hyperviscosity

Question 14

Tiny aliquot of whole blood
mixed with _____

Answer 14

0.85% normal
saline

Question 15

What is the desired dilution for RBC?

Answer 15

1:100 or 1:200

Question 16

what is the material used for the dilution?

Answer 16

glass pipette
(Thoma pipette)

Question 17

the equipment used
to count RBC and that will be focused
manually in the microscope

Answer 17

*Hemocytometer

Question 18

Diluted blood is transferred to glass
counting chamber called

Answer 18

hemacytometer

Question 19

In ___, first electronic counter
patented by ____; called ___

Answer 19

1953, Joseph and Wallace
Coulter; called Coulter counters

Question 20

Whole blood is mixed with ___

Answer 20

Drabkin reagent

Question 21

weak solution
of potassium cyanide and
potassium ferricyanide

Answer 21

Drabkin reagent

Question 22

Hemoglobin is converted to ___

Answer 22

cyanmethemoglobin
(hemiglobincyanide);

Question 23

Hemoglobin measurement for Male

Answer 23

13.5 - 18.0 g/dL

Question 24

Hemoglobin measurement for female

Answer 24

12.0 - 15.0 g/dL

Question 25

ratio of the volume of packed RBCs to volume of whole blood

Answer 25

Hematocrit

Question 26

Hematocrit is a ____

Answer 26

simply packed cell volume

Question 27

Hematocrit percentage for male

Answer 27

40 - 54 %

Question 28

Hematocrit percentage for female

Answer 28

35 - 49 %

Question 29

Reticulocytes aka

Answer 29

polychromatic (polychromatophilic) erythrocytes

Question 30

Reticulocyte is Newly released from ___

Answer 30

bone marrow (RBC production site)

Question 31

What dyes are used to diff. young RBC

Answer 31

Methylene blue dyes (nucleic acid stains or vital stains)

Question 32

WHITE BLOOD CELLS (WBCS) aka

Answer 32

leukocytes

Question 33

Function of WBC

Answer 33

Protect host from infection

Question 34

Dilution for WBC

Answer 34

1:20

Question 35

Diluent for WBC

Answer 35

dilute acid solution (to lyse RBCs)

Question 36

Leukpenia

Answer 36

below 4500/uL

Question 37

Leukocytosis

Answer 37

more than 11,500/uL

Question 38

Types of WBC that is Segmented, polymorphonuclear neutrophils/ PMNs

Answer 38

Neutrophils (NEUTs)

Question 39

engulf and destroy microorganisms

Answer 39

Phagocytic cells

Question 40

Neutrophilia means

Answer 40

(increased neutrophils) = bacterial infection

Question 41

Neutropenia means

Answer 41

(decreased neutrophils) = viral infections or certain medications

Question 42

bands are

Answer 42

Less mature (less differentiated) neutrophil

Question 43

shape of bands

Answer 43

Sausage-shaped or Horseshoe-shaped (nucleus)

Question 44

Increased bands means

Answer 44

bacterial infection

Question 45

Eosinophils are cells with ___

Answer 45

bright orange-red cytoplasmic granules

Question 46

Eosinophilia

Answer 46

(increased EOs) = allergy or parasitic infection

Question 47

Color of Eosinophil

Answer 47

(reddish granules)

Question 48

Color of Neutrophil

Answer 48

(bluish granules)

Question 49

basophils have cells with

Answer 49

dark purple cytoplasmic granules that obscure the nucleus

Question 50

the granules of Basophils contains

Answer 50

histamines

Question 51

Basophilia

Answer 51

(increased BASOs) = rare; signals hematologic disease

Question 52

high basophil leads to

Answer 52

chronic inflammation

Question 53

Lymphocytes can

Answer 53

Recognize foreign antigens and mount humoral and cell-mediated responses

Question 54

Lymphocytes is ___

Answer 54

Nearly round, slightly larger than RBCs, round nucleus and thin rim of cytoplasm

Question 55

Lymphocytosis

Answer 55

(increased LYMPHs) = viral infection

Question 56

Lymphopenia/Lymphocytop enia

Answer 56

(decreased LYMPHs) = drug therapy or immunodeficiency

Question 57

prevalent in people older than 65 y.o

Answer 57

Chronic lymphocytic

Question 58

childhood leukemia

Answer 58

Acute lymphoblastic leukemia

Question 59

Monocytes (MONOs) are

Answer 59

Immature macrophage

Question 60

Monocytes (MONOs) is the same with

Answer 60

Large WBC

Question 61

color of cytoplasm in monocytes

Answer 61

Blue-gray cytoplasm

Question 62

nucleus of mono and shape

Answer 62

Indented/folded nucleus (kidney bean shape)

Question 63

platelets aka

Answer 63

thrombocytes