Flashcards in Hematologic Diseases Deck (19):
What is the most common hemolytic anemia?
Sickle cell anemia
What is the race bias associated with sickle cell anemia?
What is another name for sickle cell anemia and why?
"Hands and feet syndrome" - patients present with pain and swelling in the hands and feet
How can sickle cell affect the patient's GI tract?
Infarct of bowel following obstruction of the mesenteric arteries (abdominal crisis)
Sickle cell presents with a predisposition for what kind of bone infection?
SALMONELLA osteomyelitis (remember the most common is usually Staph aureus, so this is super unique)
What are some of the radiographic features seen with sickle cell?
Marrow hyperplasia, hair on end skull, Erlenmeyer flask, H shaped vertebra
What are other names for the H shaped vertebrae seen with sickle cell?
Lincoln Log vertebrae, Reynold's phenomenon
What is another name for thalassemia?
What ethnicity is more likely to get thalassemia?
Those of Mediterranean origin
What are the forms of thalassemia?
Minor, intermedia, major
What is the patient presentation for thalassemia?
Fatigue due to chronic anemia, splenomegaly, cardiomegaly, gallstones
What are the features of thalassemia?
Marrow hyperplasia, extra medullary hematopoiesis, maxillary overgrown (aka rodent facies), hair on end skull
Which radiographic feature is ultra sensitive to sickle cell?
Lincoln log vertebra
Which feature is ultra sensitive to thalassemia?
Hair on end skull (also rodent facies)
Honeycomb coarsened trabeculation is seen with what condition?
Hair on end skull is more likely to be seen with what blood condition?
What is hemophilia?
Inability to clot (X-linked disease carried by females and manifested in males)
What causes the juxta-articular osteoporosis seen with hemophilia?