hematologic disorders

Question 1

lymphoid hyperplasia may effect

Answer 1

lymph nodes, waldeyer ring or oral lymphoid aggregates

Question 2

where is waldeyers ring

Answer 2

oropharynx, soft palate, lat tongue, floor or mouth

Question 3

acute and chronic lymphoid hyperplasia are

Answer 3

movable

Question 4

tx for lymphoid hyperplasia

Answer 4

no tx

Question 5

what do you include on your differential with lymphoid hyperplasia

Answer 5

lipoma and lymphoepithelial cyst

Question 6

most common cause of anemia

Answer 6

iron deficiency

Question 7

causes of iron dificiency

Answer 7

excessive blood loss, increased demands for RBCs, decreased intake, decreased absorption

Question 8

oral findings of iron deficient anemia

Answer 8

bald, burning tongue
erythema of oral mucosa
atrophy of filiform papillae
taste alteration
angular chelitis

Question 9

what do you include in your differential with iron deficient anemia

Answer 9

acute erythematous candida

Question 10

lab findings with iron deficient anemia

Answer 10

reduced hematocrit, serum iron is low

total iron binding capacity elevated

Question 11

tx for iron deficient anemia

Answer 11

treat underlying cause

supplements

Question 12

plummer vinson syndrome is characterized by

Answer 12

iron deficient anemia
dysphagia
esophageal webs
koilonychia (spoon shaped fingernails)
scc

Question 13

cause of pernicious anemia

Answer 13

deficiency of b12

Question 14

what does b12 do in blood

Answer 14

catalyst for DNA synthesis, especially in bone marrow

results in fragile megaloblastic erythrocytes

Question 15

oral manefestations of pernicious anemia

Answer 15

burning tongue, diffuse thining and erythema of oral mucosa, dorsum of tongue, usually candida

Question 16

2 systemic factors for mucosal soreness or burning

Answer 16

anemia or nutritional deficiencies

Question 17

2 local factors for mucosal soreness or burning

Answer 17

candidiasis

Question 18

t/f. candidiasis is more common for a burning tongue than anemia

Answer 18

true

Question 19

the radiographic hair on end appearance is characteristic of

Answer 19

sickle cell anemia and thalassemia

Question 20

sickle cell anemia rbc characteristics

Answer 20

deformed, rigid, sickle shaped

less o2 carrying capacity

Question 21

marrow hyperplasia is due to

Answer 21

reduced function of rbcs

Question 22

in sickle cell and thalassemia marrow hyperplasia leads to

Answer 22

a periosteal reaction leading to interspersed trabeculae

Question 23

leukemias arise where

Answer 23

cells arise in bone marrow and spread to peripheral blood

Question 24

lymphomas arise where

Answer 24

in lymph nodes and other lymphoid tissue

Question 25

t/f white blood cells neoplasms are malignant

Answer 25

true

Question 26

t/f. acute lymphocytic leukemia is predominantly in adults

Answer 26

false, children

Question 27

clinical signs of leukemia

Answer 27

anemia (fatigue, shortness of breath), leukopenia, throbocytopenia (easy bleeding) petechiae and pupura spontaneous and prolonged gingival bleeding

Question 28

oral manefestations of leukemia

Answer 28

``` extensive gingival ulceration candidosis herpetic infections (recurrent herpes) gingival enlargement (infiltration of leukemic cells ```

Question 29

acute leukemia clinically looks like

Answer 29

gingival ulceration, necrosis, and enlargement

Question 30

where does hodgkins lymphoma usually begin

Answer 30

lymph nodes

Question 31

where is the most common presenting site of hodgkins lymphoma

Answer 31

head and neck

Question 32

most cases of hodgkin lymphoma show enlargement of which nodes

Answer 32

cervical and supraclavicular lymph nodes

Question 33

reed sternberg cells

Answer 33

malignant cells of hodgkins lymphoma

Question 34

t/f hodgkin lymphoma can have cervical lymphadenopathy

Answer 34

true

Question 35

non-hodgkins usually originated from this type of wbc

Answer 35

b cells

Question 36

t/f burkitts is usually a childrens disease

Answer 36

true

Question 37

if untreated, burkitts can kill a pt in how many weeks

Answer 37

4-6 weeks

Question 38

tx for burkitts

Answer 38

intensive chemotherapy

Question 39

plasmacytoma radiographically presents as

Answer 39

a scooped out bone appearance

Question 40

multiple myeloma is a malignancy of what type of cells

Answer 40

plasma cells

Question 41

characteristics of multiple myeloma

Answer 41

bone pain, pathological fractures, fatigue (anemia), fever (neutropenia)

Question 42

well punched out radiolucent lesions are associated with what disease

Answer 42

multiple myeloma

Question 43

bence jones proteins

Answer 43

m-protein found in serum or urine of pts with multiple myeloma

Question 44

eosiniphilic granuloma

Answer 44

langerhans cells disease with one radiolucent area

Question 45

chronic disseminated histiocytosis

Answer 45

langerhans cells disease with bone lesions, exophthalamus, DI

Question 46

langerhans has a radiographic appearance of

Answer 46

a scooped out appearance with "teeth floating in the air" | looks like periodontitis with alveolar bone loss

Question 47

3 types of langerhans cell diseases

Answer 47

eosiniphilic granuloma, chronic and acute disseminated histiocytosis

Question 48

t/f burkitts lymphoma has the starry sky appearance

Answer 48

true