hematology

Question 1

described platelets as “petites plaques”

Answer 1

Guilio Bizzozero

Question 2

Discovery of erythrocytes by (?)

Answer 2

Swammerdam

Question 3

The scientific term for cell appearance is (?), which encompasses cell color, size, shape, cytoplasmic inclusions, and nuclear condensation

Answer 3

morphology

Question 4

gold standard for hemoglobin determination

Answer 4

cyanmethemoglobin (HiCN) method

Question 5

Development of Wright’s stain by (?)

Answer 5

James Homer Wright

Question 6

Human erythrocytes was described by (?)

Answer 6

Anton Van Leeuwenhoek

Question 7

Average pH of (?)

Answer 7

7.40 (7.35– 7.45)

Question 8

• Adult male: (?) liters
• Adult female: (?) liters
• Newborn: (?) ml

Answer 8

• 5-6
• 4-5
• 250-350

Question 9

Physicians rely on hematology laboratory test results to select and monitor therapy for these disorders; consequently, a (?) is ordered on nearly everyone who visits a physician or is admitted to a hospital

Answer 9

complete blood count (CBC)

Question 10

Some hematologists prefer to call platelets as (?)

Answer 10

“cell fragments”

Question 11

If central pallor is < 1/3 of the cell

Answer 11

increased hgb concentration (hyperchromic RBC)

Question 12

are closely observed because they indicate the ability of the bone marrow to increase RBC production in anemia caused by blood loss or excessive RBC destruction

Answer 12

reticulocyte

Question 13

based on the principle of electric impedance

Answer 13

Coulter counter

Question 14

hemoglobin

Relies on a weak solution of potassium cyanide and potassium ferricyanide, called (?)

Answer 14

Drabkin reagent

Question 15

(?) (polychromatic, a mixture of acidic and basic dyes), and refinements thereof, remains the foundation of blood cell identification

Answer 15

Wright’s Romanowsky-type stain

Question 16

plasma

• Pink: (?)
• Red: (?)
• Yellow-brown: (?)
• milky/turbid: (?)

Answer 16

• slight hemolysis
• gross hemolysis
• icteric plasma
• Lipemia

Question 17

If central pallor is >1/3 of the cell

Answer 17

decreased hgb concentration (hypochromic RBC)

Question 18

(?) is often referred to as the packed cell volume (PCV)

Answer 18

Hematocrit

Question 19

Automated analyzers- ionic surfactant (detergent) (?) to reduce environmental cyanide

Answer 19

sodium lauryl sulfate

Question 20

plasma contains (?)

Answer 20

fibrinogen

Question 21

First complete classification of leukocytes by (?)

Answer 21

Paul Ehrlich

Question 22

(?) stains are dyes absorbed by live cells

Answer 22

Vital (or “supravital”)

Question 23

Describe worms in the blood by (?)

Answer 23

Athanasius Kircher

Question 24

RBC, WBC, and platelet appearance is analyzed through automation or visually using light microscopy examination of cells fixed to a glass microscope slide and stained with (?)

Answer 24

Wright or Wright-Giemsa stain

Question 25

Young RBCs contain remnants of (?) in its cytoplasm

Answer 25

ribonucleic acid (RNA)

Question 26

(?) general term for mature erythrocytes that have a shape other than the normal round, biconcave appearance (variation in cell shape)

Answer 26

Poikolocytosis

Question 27

a specialized connective tissue; average volume is (?) liters (adult)

Answer 27

5

Question 28

RBC diluting fluid– (?) (RBCs retain their shape, matches osmolality of blood) ; example is (?); lyses WBC’s

Answer 28

* isotonic solution * 0.85% NSS

Question 29

PMN distinguished from other leukocytes by (?)

Answer 29

Wharton Jones

Question 30

(?) general term used in hematology to denote an increased variation in cell size

Answer 30

Anisocytosis

Question 31

* In vivo, blood is red and is in the (?) state * in vitro, coagulates in (?) minutes

Answer 31

* fluid * 5-10

Question 32

Stained by methylene blue dyes

Answer 32

reticulocyte

Question 33

Average specific gravity of (?)

Answer 33

1.055