Hematology 2

Question 1

Most common cardiac involvement in haemochromatosis

Answer 1

Congestive heart failure

Question 2

Bilateral lymphadenopathy

Answer 2

CLL

Question 3

Crazy massive spleen

Answer 3

CML

Question 4

Oral problems: gingivitis
Anaemia
Bruising and bleeding

Answer 4

AML

Question 5

Painless lymphadenopathy

Answer 5

Hodgkin lymphoma

Question 6

Anaemia and constipation

Next step

Answer 6

Colonoscopy

Question 7

Differentiator of
haemolytic anaemia

Answer 7

Low haptoglobin

Question 8

Low serum iron but normal transferrin saturation

And chronic disease - like RA

Answer 8

Anaemia of chronic disease

Question 9

Basophillic stippling or target cells

Answer 9

Lead poisoning

Question 10

Hypersegmentation of neutrophils

Answer 10

Megaloblastic anaemia

Folate or cobalamin

If no neurological signs - folate

(Often after being drinking)

Question 11

What cannot help iron overload?

Answer 11

Exercise

Question 12

Most profound adverse effect of transfusion iron overload

Answer 12

Hepatic cirrhosis

Death from liver disease

Question 13

APlastic anaemia can be caused by

Answer 13

NSAIDs- diclofenac

Question 14

Increased MCV 

Answer 14

Megaloblasts - B12 or folic

B12 is pernicious anaemia

Question 15

Empty fatty bone marrow

Answer 15

Aplastic anaemia

Question 16

Anaemia plus splenomegaly

Answer 16

Myelodysplasia

Question 17

Hemochromatosis inheritance

Answer 17

Autosomal recessive

Question 18

Iron deficiency anaemia test

Answer 18

Low serum ferritin

Question 19

Anaemia after gastric bypass surgery

Answer 19

B12

Question 20

Carbimazole + fever and sore throat due to low neutrophils

Answer 20

Carbimazole induced agranularcytosis

Question 21

Extramedillary hemopoiesis is a feature of

Answer 21

Thalassemia

Question 22

Haemolytic anaemia +
Parvovirus

Answer 22

Aplastic anaemia/crisis

Question 23

Splenomegaly
Macrocytic anaemia

Answer 23

Consider myelodisplasia

Question 24

Renal failure = Liguria
Abdominal pain
Diarrhoea

Answer 24

Hemolytic uremia syndrome

Question 25

Coombs test positive means

Answer 25

Autoimmune nature of haemolysis In spherocytosis it’s negative

Question 26

Thrombocytopenia and DVT inpatient on heparin

Answer 26

Stop heparin Heparin induced thrombocytopenia

Question 27

Positive cross match will lead to

Answer 27

Rejection of the graft O is universal donor A.B is universal recipient

Question 28

Most common site in gastrointestinal tract for non-Hodgkin lymphoma

Answer 28

Stomach

Question 29

Earliest symptom of sickle cell disease

Answer 29

Bone infarction

Question 30

Thalassemia diagnosis

Answer 30

Hb electrophoresis

Question 31

Bleeding in myeloproliferative neoplasms is

Answer 31

Mucocutaneous

Question 32

Prolonged bleeding after trauma and heavy periods

Answer 32

Von Willebrand disease

Question 33

CLL treatment first line

Answer 33

Prednisolone

Question 34

Painless, peripheral lymphadenopathy and no other symptoms

Answer 34

Follicular lymphoma - common form of non-Hodgkin lymphoma BCL-2 over expression

Question 35

Aortic valve protheses causes destruction of erythrocytes, they’re called

Answer 35

Schistocytes or helmet cells Haemolysis causes increased LDH

Question 36

Hemochromatosis - 90% of patients are homozygous

Answer 36

For C282Y In Australia 1 in 200

Question 37

Disseminated intravascular coagulation

Answer 37

Bleeding at Vini puncture or trauma site APTT, PT and bleeding time prolonged

Question 38

Von Willebrand testing

Answer 38

APTT and bleeding time prolonged Haemophilia - only APTT prolonged

Question 39

Auer rods - inclusion Body in myeloid blast cells

Answer 39

AML