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Pance > Hematology > Flashcards

Hematology Flashcards

0
Q

Hypersegmented neutrophils

A

B12 and folate deficiency

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1
Q

Rouleaux formation

A

Multiple myeloma ++

Infection/inflammation

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2
Q

Howell-jolly bodies

A

Splenectomized pts

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3
Q

Target cells

A

Sickle cell dz, thalassemia

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4
Q

Basophilic stippling/ringed sideroblasts

A

Lead poisoning

Sideroblastic anemia

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5
Q

Low serum iron
Low ferritin
High TIBC

A

Iron deficiency anemia

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6
Q

Low serum iron
High ferritin
Low TIBC

A

Anemia of chronic disease

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7
Q

Microcytic anemia

Normal serum iron

A

Thalassemia

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8
Q

Inciting factors for G6PD anemia

A

Infection
Sulfa
Fava beans
Antimalarials

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9
Q

TTP/HUS

A

TCP
Nl PT/PTT

HUS - kidney dysfunction

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10
Q

TTP/HUS rx

A

Plasmapheresis

May hold off in peds with HUS

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11
Q

Labs in DIC

A

Elevated PT/PTT
TCP
Schistocytes
Decreased fibrinogen

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12
Q

ITP labs

A

Isolated TCP

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13
Q

Hemophilia A rx

A

Factor VIII infusion

+/- desmopressin

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14
Q

Hemophilia B rx

A

Factor IX infusion

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15
Q

Von Willebrand disease rx

A

Desmopressin +/- factor VIII

16
Q

Hodgkin lymphoma presentation

A

Upper body painless LAD - pain with etoh

B symptoms

17
Q

Hodgkin lymphoma dx

A

Reed-Sternberg cells

18
Q

Non-Hodgkin lymphoma presentation

A

Painless peripheral LAD

Extra-nodal sites - GI, skin, CNS

19
Q

Multiple myeloma dx

A

Monoclonal protein spike
Urine bence-jones proteins
Rouleaux formation
Punched out bone lesions

20
Q

ALL

A

Peds

Bone marrow hypercellular with >20% blasts

21
Q

CLL

A

MC leukemia in adults

Smudge cells

Asymptomatic

22
Q

AML

A

Auer rods

> 20% blasts

Risk of tumor lysis syndrome

23
Q

CML

A

Philadelphia chromosome

High WBC

24
Q

Auer rod

A

AML

25
Q

Philadelphia chromosome

A

CML

26
Q

Reed-Sternberg cells

A

Hodgkin lymphoma

27
Q

Polycythemia Vera rx

A

Phlebotomy + hydroxyurea

Pance (1 decks)

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